Epsilon4 Allele Carriers Show Altered Brain Activity Before Onset Of Alzheimer''s Symptoms

... Healthy individuals who are at risk of Alzheimer''s disease show reduced activity in the hippocampal region of the brain when performing tasks related to forming new memories. In a study published today in the open access journal BMC Medicine, individuals carrying the apolipoprotein E (APOE) epsilon4 allele, which has previously been associated with high risk of developing Alzheimer''s disease (AD), showed altered brain activity compared to APOE epsilon3 homozygotes... click link for more info. ...