Relationship Between Painful Bladder Syndrome And Idiopathic Orthostatic Cyclic Edema Is Postulated

... UroToday.com - Described over 50 years ago, the condition known as idiopathic orthostatic cyclic edema is associated with nocturia, chronic refractory urticaria and failure to lose weight. It is thought that a defect in the response from the sympathetic nerve endings allows water to leak from intravascular to extravascular spaces in the orthostatic position. [click link for full article] ...