Kiss1 Neurons And Neuroendocrine Regulation

... Mammalian ovulation is the culmination of a complex neurohormonal signaling pathway. Gonadotropin-releasing hormone (GnRH) is normally under tonic negative feedback control, but estrogen triggers a GnRH/luteinizing hormone (LH) surge that leads to ovulation. This week, Smith et al. investigated the kisspeptins as potential mediators of this signaling cascade. [click link for full article] ...