Activating EAAT4 Anion Channels

... The excitatory amino acid transporter 4 (EAAT4) is an unusual beast. Expressed predominantly in cerebellum Purkinje cells rather than glia, the molecule also functions as an anion-selective ion channel. The current model for transport is that a molecule of glutamate is transported independently by each subunit in the homotrimeric transporter. [click link for full article] ...