EGFR And Reactive Astrocytes

... In this week's Journal, Liu et al. provide some insight on what makes a "reactive" astrocyte reactive. The authors look at activated astrocytes using several models of optic nerve injury. The epidermal growth factor receptor (EGFR) was not expressed by quiescent astrocytes but was upregulated in rat optic nerve astrocytes after ischemia, nerve transection, and in a chronic glaucoma model. [click link for full article] ...