Preventing Ventilation Induced Lung Injury Depends On Giving The Right Number Of 'Sighs'

... Periodic deep inflation (akin to a sigh) combined with low tidal volume provides the best balance between keeping the lung open and preventing ventilator-induced lung injury, a study of ventilation therapy shows. The study with mice also clearly demonstrates that there is an optimal number of deep inflations. Ventilation therapy is used with patients who cannot breathe on their own because of trauma, lung injuries and chronic lung disease. ...