New Gene Uncovered For Late-onset Alzheimer's; Findings Replicated In Four Different Ethnic Groups

... An international team of researchers, led by Columbia University Medical Center, Boston University School of Medicine and the University of Toronto, has uncovered a major new gene -- SORL1 -- implicated in late-onset Alzheimer's disease. Replicated in four distinct ethnic groups, SORL1 is only the second genetic variant for late-onset Alzheimer's, the type of Alzheimer's found in 90 percent of people with this devastating disease. ApoE4, the first, was identified in 1993. ...