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Leukodystrophy as related to Alexander Disease


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Leukodystrophies 

ALX; AxD; demyelinogenic leukodystrophy; dysmyelinogenic leukodystrophy; fibrinoid degeneration of astrocytes; leukodyst... 

Leukodystrophy refers to progressive degeneration of the white matter of the brain due to imperfect growth or development of the myelin sheath, the fatty covering that acts as an insulator around nerve fiber. Myelin, which lends its color to the white matter of the brain, is a complex substance made up of at least ten different chemicals. The leukodystrophies are a group of disorders that are caused by genetic defects in how myelin produces or metabolizes these chemicals. Each of the leukodystro...

Alexander disease is a rare, genetically determined degenerative disorder of the central nervous system. It is one of a group of disorders known as the leukodystrophies, diseases that result from imperfect growth or development of the myelin sheath, the fatty covering that acts as an insulator around nerve fibers in the brain. Myelin, which lends its color to the "white matter" of the brain, is a complex substance made up of at least ten different chemicals. Each of the leukodystrophies affects ...


Leukodystrophy as related to Alexander Disease


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August 21, 2008


Page Updated: June 12, 2007
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