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Shingles as related to Phenytoin


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Herpes Zoster; Post-herpetic Neuralgia 

Dilantin; Dilantin Kapseals; Phenytek 

Herpes zoster, colloquially known as shingles, is the reactivation of varicella zoster virus, leading to a crop of painful blisters over the area of a dermatome. It occurs very rarely in children and adults, but its incidence is high in the elderly (over 60), as well as in any age group of immunocompromised patients. It strikes 500,000 people per year in the United States. Treatment is generally with acyclovir. Many develop a painful condition termed postherpetic neuralgia.

Phenytoin sodium (marketed as Dilantin® in the USA and as Epanutin® in the UK, by Parke-Davis, now part of Pfizer) is a commonly used antiepileptic. It was approved by the Food and Drug Administration in 1953 for use in seizures.


Shingles as related to Phenytoin


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October 8, 2008


Page Updated: June 12, 2007
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