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Dermatomyositis as related to Azathioprine


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Dermatomyositis is one of a group of acquired muscle diseases called inflammatory myopathies. The disease, which has a somewhat severe onset, affects both children and adults. Females are more often affected than males. Dermatomyositis is characterized by a rash accompanying, or more often, preceding muscle weakness. The rash looks like patchy, bluish-purple discolorations on the face, neck, shoulders, upper chest, elbows, knees, knuckles, and back.

Azathioprine is a chemotherapy drug, now rarely used for chemotherapy but more for immunosuppression in organ transplantation and autoimmune disease such as rheumatoid arthritis or Crohn's disease. It is a pro-drug, converted in the body to the active metabolite 6-mercaptopurine.


Dermatomyositis as related to Azathioprine


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July 25, 2008


Page Updated: June 12, 2007
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