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Proton-pump Inhibitors as related to GERD


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Acid Reflux; Gastroesophageal Reflux; Gastroesophageal Reflux (GERD); Gastroesophageal Reflux Disease; Gastroesophageal ... 

Chemicals that suppress stomach acid secretion by inhibiting a specific enzyme system on the surface of the stomach's parietal cells. This enzyme system is regarded as the acid (proton) pump within the stomach mucosa (for example, omeprazole [Prilosec®]).

Gastroesophageal reflux disease, or GERD, occurs when the lower esophageal sphincter (LES) does not close properly and stomach contents leak back, or reflux, into the esophagus. The LES is a ring of muscle at the bottom of the esophagus that acts like a valve between the esophagus and stomach. The esophagus carries food from the mouth to the stomach.


Proton-pump Inhibitors as related to GERD


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October 8, 2008


Page Updated: June 12, 2007
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