http://goldbamboo.com/ Ataxia Telangiectasia News from GoldBamboo.com en-us © 2005, Gold Bamboo LLC, All Rights Reserved http://goldbamboo.com/news-a218317.html If you bend a knee or an elbow, the nerves in your limbs stretch but do not break. A University of Utah study suggests why: A gene produces a springy protein that keeps nerve cells flexible. When the gene was disabled in tiny nematode worms, their nerve cells literally broke. The discovery may provide a new explanation for spinocerebellar ataxia type 5 (SCA5) -- a disease previously tied to a human version of the gene and identified in 11 generations of U.S. President Abraham Lincoln's family, starting with his paternal grandparents. SCA5 may have afflicted Lincoln himself. The new study suggests how. Wed, 31 Jan 2007 04:00 EST http://goldbamboo.com/news-a195342.html In the new study, the researchers tested a variety of compounds that inhibited a class of enzymes known as histone deacetylases in a cell line derived from blood cells from a Fredreich's ataxia sufferer. One of these inhibitors had the effect of reactivating the frataxin gene, which is silenced in those with the disease. [click link for full article] Fri, 25 Aug 2006 12:00 EST http://goldbamboo.com/news-a195177.html A team from the Scripps Research Institute and the University of California School of Medicine has developed compounds that reactivate the gene responsible for the neurodegenerative disease Friedreich's ataxia, offering hope for an effective treatment for this devastating and often deadly condition. Wed, 23 Aug 2006 03:00 EST http://goldbamboo.com/news-a190108.html Inbal Dar, Sharon Biton, Yosef Shiloh, and Ari BarzilaiCellular DNA damage such as double-strand breaks sets off restorative signaling cascades. One of these molecules is the protein kinase ataxia-telangiectasia mutated (ATM). [click link for full article] Fri, 21 Jul 2006 01:00 EST http://goldbamboo.com/news-a179430.html WASHINGTON, May 8 /PRNewswire/ -- Friedreich's ataxia patients andfamilies have more reason than ever to welcome the approach of"Friedreich's Ataxia Awareness Day" on May 20th. The third Saturday of Mayis recognized in Congressional and state proclamations and through variousevents around the country as "Friedreich's Ataxia Awareness Day... click link for more info. Tue, 09 May 2006 06:00 EST