Amyotrophic Lateral Sclerosis |
Als; Amyotrophic Lateral Sclerosis (ALS); Amyotrophic lateral sclerosis, type 2; Amyotrophic lateral sclerosis, type 4; Amyotrophic Lateral Sclerosis/als; autosomal dominant juvenile ALS; autosomal recessive form of juvenile ALS type 3; Charcot disease; dHMN; FALS; familial amyotrophic lateral sclerosis; juvenile amyotrophic lateral sclerosis; Lou Gehrig Disease; Lou Gehrig's Disease; Lou Gehrig//'s disease; Motor Neuron Disease, Amyotrophic Lateral Sclerosis; neuronopathy, distal hereditary motor, with pyramidal features; RFALS type 3 |
Amyotrophic lateral sclerosis (ALS, sometimes called Lou Gehrig's disease, Maladie de Charcot or motor neurone disease) is a progressive, almost invariably fatal neurological disease. Description In ALS, Amyotrophic Lateral Sclerosis, both the upper motor neurons and the lower motor neurons degenerate or die, ceasing to send messages to muscles. Unable to function, the muscles gradually weaken, waste away (atrophy), and have fasciculations because of denervation. Eventually, the ability ...
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Amyotrophic Lateral Sclerosis Clinical Trials
- Familial Amyotrophic Lateral Sclerosis. A Preliminary Study to Identify Subjects Who Might Be Willing to Participate in a Randomized Controlled Trial
ClinicalTrials.gov Identifier: NCT00136500 - Recruiting
Amyotrophic Lateral Sclerosis
- Safety Study of Oral Sodium Phenylbutyrate in Subjects with ALS (Amyotrophic Lateral Sclerosis)
ClinicalTrials.gov Identifier: NCT00107770 - Active, not recruiting
Amyotrophic Lateral Sclerosis
- R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00140218 - Recruiting
Amyotrophic Lateral Sclerosis
- Determinants of Disease Severity in Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00004457 - Active, not recruiting
Amyotrophic Lateral Sclerosis
- Exposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00339976 - Active, not recruiting
Amyotrophic Lateral Sclerosis; ALS
- Early Treatment of Amyotrophic Lateral Sclerosis (ALS) with Nutrition and Non-Invasive Positive Pressure Ventilation (NIPPV)
ClinicalTrials.gov Identifier: NCT00116558 - Active, not recruiting
Amyotrophic Lateral Sclerosis
- Study of Creatine Monohydrate in Patients with Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00069186 - Active, not recruiting
Amyotrophic Lateral Sclerosis (ALS)
- A 12-week, multicenter, safety and dose-ranging study of 3 oral doses of TCH346 in patients with Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00036413 - Completed
Amyotrophic Lateral Sclerosis
- Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00537446 - Recruiting
Amyotrophic Lateral Sclerosis; Motor Neuron Disease
- Amyotrophic Lateral Sclerosis Web Based Patient Care Database: ALSConnection.Org
ClinicalTrials.gov Identifier: NCT00302198 - Recruiting
Amyotrophic Lateral Sclerosis
- Confirmation of Self-Reported Amyotrophic Lateral Sclerosis Cases in the AARP-Diet and Health Study
ClinicalTrials.gov Identifier: NCT00377351 - Recruiting
Amyotrophic Lateral Sclerosis
- Study Evaluating TCH346 and Placebo Administered Once Daily in Patients with Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov Identifier: NCT00072709 - Completed
Amyotrophic Lateral Sclerosis
- Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00005766 - Completed
Amyotrophic Lateral Sclerosis
- Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov Identifier: NCT00326625 - Recruiting
Amyotrophic Lateral Sclerosis
- Molecular Imaging Modality by Positron Emission Tomography Using 18F-X : Study of Microglial Activation in Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00563537 - Recruiting
Amyotrophic Lateral Sclerosis; Bulbar Disease; Spinal Disease
- Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III
ClinicalTrials.gov Identifier: NCT00415519 - Recruiting
Amyotrophic Lateral Sclerosis (ALS)
- Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov Identifier: NCT00424463 - Recruiting
Amyotrophic Lateral Sclerosis (ALS)
- Genetic Epidemiology of Familial Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov Identifier: NCT00317616 - Recruiting
Amyotrophic Lateral Sclerosis
- Safety and Efficacy Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients with ALS
ClinicalTrials.gov Identifier: NCT00125203 - Active, not recruiting
Amyotrophic Lateral Sclerosis; Sialorrhea
- Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov Identifier: NCT00403104 - Recruiting
Amyotrophic Lateral Sclerosis (ALS)
- A Study of the Expression of Nogo and Reticulon Genes in Skeletal Muscle of Patients With Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00213824 - Recruiting
Amyotropic Lateral Sclerosis
- Motor-Point Stimulation for Conditioning the Diaphragm of Patients With Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov Identifier: NCT00420719 - Recruiting
Amyotrophic Lateral Sclerosis (ALS)
- The Effect of Intensive Controlled Exercise in the Early Stages of Amyotrofic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00160004 - Recruiting
Amyotrophic Lateral Sclerosis
- Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS)
ClinicalTrials.gov Identifier: NCT00353665 - Recruiting
Amyotrophic Lateral Sclerosis
- Is there a higher than expected occurrence of Amyotrophic Lateral Sclerosis (ALS) among deployed veterans as compared to non-deployed Gulf War veterans?
ClinicalTrials.gov Identifier: NCT00007722 - Completed
Amyotrophic Lateral Sclerosis
- Clinical trial of creatine in amyotrophic lateral sclerosis [ALS]
ClinicalTrials.gov Identifier: NCT00005674 - Completed
Amyotrophic Lateral Sclerosis
- Creatine for the Treatment of Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00070993 - Completed
Amyotrophic Lateral Sclerosis
- Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00334516 - Recruiting
Cerebral Cortex Dysfunction
- A Long-Term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS)
ClinicalTrials.gov Identifier: NCT00230074 - Completed
Amyotrophic Lateral Sclerosis
- Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00023075 - Completed
Primary Lateral Sclerosis; Hereditary Spastic Paraplegia; Amyotrophic Lateral Sclerosis
- G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response
ClinicalTrials.gov Identifier: NCT00397423 - Completed
Amyotrophic Lateral Sclerosis
- A Randomised Sequential Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00136110 - Completed
Amyotrophic Lateral Sclerosis (ALS)
- Minocycline to Treat Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00047723 - Completed
Amyotrophic Lateral Sclerosis
- Exogenous Toxicants and Genetic Susceptibility in ALS
ClinicalTrials.gov Identifier: NCT00011154 - Completed
Amyotrophic Lateral Sclerosis
- Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00355576 - Completed
Amyotrophic Lateral Sclerosis
- IGF-1/ALS Trial
ClinicalTrials.gov Identifier: NCT00035815 - Completed
Amyotrophic Lateral Sclerosis
- Frontotemporal Dementia and Amytrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00140777 - Recruiting
Frontotemporal dementia; and/or; Lateral amyotrophic sclerosis
- Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease
ClinicalTrials.gov Identifier: NCT00324454 - Active, not recruiting
Motor Neuron Disease; Amyotrophic Lateral Sclerosis; Primary Lateral Sclerosis; Progressive Muscular Atrophy
- Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS
ClinicalTrials.gov Identifier: NCT00021697 - Completed
Amyotrophic Lateral Sclerosis
- Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS)
ClinicalTrials.gov Identifier: NCT00231140 - Terminated
Amyotrophic Lateral Sclerosis (ALS)
- Effects of Gastrostomy on Amyotrophic Lateral Sclerosis
ClinicalTrials.gov Identifier: NCT00337402 - Completed
Amyotrophic Lateral Sclerosis
- Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS]
ClinicalTrials.gov Identifier: NCT00214110 - Completed
Amyotrophic Lateral Sclerosis (ALS)
- Clinical Trial of High Dose CoQ10 in ALS
ClinicalTrials.gov Identifier: NCT00243932 - Active, not recruiting
Amyotrophic Lateral Sclerosis; Lou Gehrig's Disease
- Safety testing of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Laughter & Crying)
ClinicalTrials.gov Identifier: NCT00056524 - Completed
Amyotrophic Lateral Sclerosis; Multiple Sclerosis; Alzheimer's Disease; Stroke; Traumatic Brain Injury
- Mitochondrial Functions and Oxidative Stress in ALS Patients
ClinicalTrials.gov Identifier: NCT00331812 - Recruiting
Amyotrophic Lateral Sclerosis
- Efficacy of Noninvasive Ventilation in ALS
ClinicalTrials.gov Identifier: NCT00537641 - Recruiting
Amyotrophic Lateral Sclerosis; Motor Neuron Disease
- Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS
ClinicalTrials.gov Identifier: NCT00372879 - Recruiting
Amyotrophic Lateral Sclerosis
- The Effect of Memantine on Functional Outcomes and Motor Neuron Degeneration in ALS
ClinicalTrials.gov Identifier: NCT00409721 - Recruiting
Amyotrophic Lateral Sclerosis
- Influence of G-CSF and EPO on Associative Learning and Motor Skills
ClinicalTrials.gov Identifier: NCT00298597 - Recruiting
Chronic Stroke; Amyotrophic Lateral Sclerosis
- Clinical Trial Ceftriaxone in Subjects With ALS
ClinicalTrials.gov Identifier: NCT00349622 - Recruiting
Amyotrophic Lateral Sclerosis; ALS
- A Long-Term Study in Patients With ALS
ClinicalTrials.gov Identifier: NCT00445172 - Recruiting
Amyotrophic Lateral Sclerosis (ALS)
- A Phase II/III Study in Patients With ALS
ClinicalTrials.gov Identifier: NCT00444613 - Recruiting
Amyotrophic Lateral Sclerosis (ALS)
- Pilot Placebo-Controlled Trial of Early Noninvasive Ventilation for ALS
ClinicalTrials.gov Identifier: NCT00580593 - Recruiting
Amyotrophic Lateral Sclerosis; ALS
- A Multicenter, Double-Blind Study to Investigate the Safety and Efficacy of Arimoclomol in Volunteers With ALS
ClinicalTrials.gov Identifier: NCT00561366 - Not yet recruiting
Amyotrophic Lateral Sclerosis
- Phase II Study Using Thalidomide for the Treatment of ALS
ClinicalTrials.gov Identifier: NCT00140452 - Completed
Amyotrophic Lateral Sclerosis; ALS
- Derivation of Primary Donor Cell Lines for Human Somatic Cell Nuclear Transfer
ClinicalTrials.gov Identifier: NCT00553826 - Recruiting
Parkinson Disease; Amyotrophic Lateral Sclerosis; Diabetes, Type I
- Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
ClinicalTrials.gov Identifier: NCT00159198 - Terminated
Frontotemporal dementia; Lateral amyotrophic sclerosis
- CARE Canadian ALS Riluzole Evaluation
ClinicalTrials.gov Identifier: NCT00542412 - Completed
Amyotrophic Lateral Sclerosis
- Study of the Effects Strengthening Exercises in Individuals With ALS
ClinicalTrials.gov Identifier: NCT00204464 - Completed
Amyotrophic Lateral Sclerosis
- Phase II Study of Leuprolide and Testosterone for Men with Kennedy's Disease or Other Motor Neuron Disease
ClinicalTrials.gov Identifier: NCT00004771 - Completed
Spinal Muscular Atrophy; Amyotrophic Lateral Sclerosis; Spinobulbar Muscular Atrophy
- Noninvasive Ventilation in ALS Patients With Mild Respiratory Involvement
ClinicalTrials.gov Identifier: NCT00386464 - Completed
Amyotrophic Lateral Sclerosis
- A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS
ClinicalTrials.gov Identifier: NCT00244244 - Completed
Amyotrophic Lateral Sclerosis (ALS)
- Non-Invasive Ventilation in ALS
ClinicalTrials.gov Identifier: NCT00560287 - Not yet recruiting
Amiotrophyc Lateral Sclerosis; Chrinic Respiratory Failure
- Isolated Mild Fetal Ventriculomegaly and Neurodevelopmental Outcome
ClinicalTrials.gov Identifier: NCT00256906 - Recruiting
Lateral Ventricles
- BEYOND Study - Betaferon/Betaseron Efficacy Yielding Outcomes of a New Dose in Multiple Sclerosis (MS) Patients
ClinicalTrials.gov Identifier: NCT00099502 - Active, not recruiting
Multiple Sclerosis
- Safety of RG2077 in Patients With Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00076934 - Active, not recruiting
Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting
- Rebif® New Formulation in Relapsing Forms of Multiple Sclerosis (RMS)
ClinicalTrials.gov Identifier: NCT00110396 - Active, not recruiting
Multiple Sclerosis
- Combination Therapy with Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00037102 - Active, not recruiting
Multiple Sclerosis
- A Study to Evaluate Rituximab in Adults with Relapsing Remitting Multiple Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00097188 - Active, not recruiting
Multiple Sclerosis
- A Study to Evaluate the Safety and Efficacy of Rituximab in Adults with Primary Progressive Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00087529 - Active, not recruiting
Multiple Sclerosis
- Auditory Function in Patients With and Without Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00037947 - Recruiting
Multiple Sclerosis
- Efficacy Study of Prolotherapy Vs Corticosteroid for Tennis Elbow
ClinicalTrials.gov Identifier: NCT00160303 - Recruiting
Lateral epicondylitis
- Immunotherapy with BHT-3009 Alone or Combined with Atorvastatin in Patients with Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00103974 - Active, not recruiting
Multiple Sclerosis
- Safety Study of RTL1000 (Recombinant T Cell Receptor Ligand) in Subjects With Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00411723 - Recruiting
Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting
- Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients with Systemic Sclerosis
ClinicalTrials.gov Identifier: NCT00006393 - Recruiting
Systemic Sclerosis
- EARLY IFNb-1a and Atorvastatin Combination Therapy of Isolated Clinical Syndrome Suggestive of Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00137176 - Recruiting
Multiple Sclerosis
- EARLY IFNB-1a and Simvastatin Combination Therapy in Clinically Isolated Syndrome Suggestive of Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00146068 - Recruiting
Multiple Sclerosis
- Evaluation of Efficiency of Ritalin in Multiple Sclerosis (MS) Patients
ClinicalTrials.gov Identifier: NCT00220493 - Recruiting
Relapsing Remitting Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive
- Lateral Epicondylitis Iontophoresis Randomized Control Trial (LERCT)
ClinicalTrials.gov Identifier: NCT00435318 - Not yet recruiting
Lateral Epicondylitis
- Improving Memory in Patients with Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00062972 - Recruiting
Multiple Sclerosis
- Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)
ClinicalTrials.gov Identifier: NCT00001248 - Recruiting
Multiple Sclerosis
- Magnetic Resonance Imaging to Detect Brain Damage in Patients with Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00099307 - Recruiting
Multiple Sclerosis
- Efficacy and Safety of Fingolimod in Patients With Relapsing-Remitting Multiple Sclerosis With Optional Extension Phase
ClinicalTrials.gov Identifier: NCT00340834 - Active, not recruiting
Multiple Sclerosis
- Safety and Efficacy Study of Doxycycline in Combination With Interferon-B-1a to Treat Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00246324 - Active, not recruiting
Multiple Sclerosis
- GER-009-06-AVX Early Therapy in Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00492570 - Active, not recruiting
Relapsing-Remitting Multiple Sclerosis
- Extension Study to Evaluate Safety, Tolerability and Effects on Efficacy Parameters of FTY720 in Patients With Relapsing Multiple Sclerosis.
ClinicalTrials.gov Identifier: NCT00235430 - Active, not recruiting
Multiple Sclerosis
- Prospective, Open-Label Tolerability and Safety Monitoring Study of Novantrone in a Selected Cohort of Multiple Sclerosis Patients
ClinicalTrials.gov Identifier: NCT00262314 - Active, not recruiting
Multiple Sclerosis
- Zenapax to Treat Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00001934 - Active, not recruiting
Multiple Sclerosis
- Efficacy and Safety of Fingolimod in Patients With Relapsing-Remitting Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00289978 - Active, not recruiting
Multiple Sclerosis
- Immunological Mechanisms of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00342134 - Active, not recruiting
Multiple Sclerosis
- Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00381264 - Active, not recruiting
Multiple Sclerosis
- Phase III Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Immune Globulin for Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00004744 - Active, not recruiting
Multiple Sclerosis
- Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00179478 - Active, not recruiting
Multiple Sclerosis; Optic Neuritis; Transverse Myelitis; Acute Brainstem/Cerebellar Syndrome
- POPART''MUS : Prevention of Post Partum Relapses with Progestin and Estradiol in Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00127075 - Recruiting
Multiple Sclerosis
- Multimodal MRI in Multiple Sclerosis (MS): Reliability and Follow Up
ClinicalTrials.gov Identifier: NCT00289159 - Active, not recruiting
Multiple Sclerosis
- Atorvastatin Therapy in Patients With Clinically Isolated Syndrome (CIS) at Risk for Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00094172 - Recruiting
Multiple Sclerosis
- Treatment of Multiple Sclerosis with Copaxone and Albuterol
ClinicalTrials.gov Identifier: NCT00039988 - Active, not recruiting
Autoimmune Diseases; Multiple Sclerosis
- Combination Therapy of Betaseron-Prograf in Multiple Sclerosis
ClinicalTrials.gov Identifier: NCT00298662 - Active, not recruiting
Multiple Sclerosis
- Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone
ClinicalTrials.gov Identifier: NCT00004645 - Active, not recruiting
Acute Disseminated Encephalomyelitis; Devic's Syndrome; Marburg's variant of multiple sclerosis; Balo's Concentric Sclerosis; ...
- Follow-up Study of the BENEFIT Study (Betaferon® / Betaseron® in Newly Emerging Multiple Sclerosis for Initial Treatment)
ClinicalTrials.gov Identifier: NCT00185211 - Active, not recruiting
Multiple Sclerosis

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