The purpose of this study is to determine whether a telephone counseling intervention can enhance the quality of life for women with cervical cancer. This study will also determine whether reduced stress has an effect on hormonal and immune responses in these women.

Cervical cancer patients often experience significant physical and emotional stress. Unfortunately, there is a lack of literature on stress treatments in this population. Mind-body interventions that include strategies to manage stress, enhance coping, and solve adjustment-related problems have demonstrated clear benefits in improving overall health. This study will examine the feasibility and benefits of a psychosocial telephone counseling (PTC) intervention and will determine whether long-term improvements in quality of life are associated with changes in neuroendocrine and immune parameters.

Participants in this study will be randomly assigned to receive 4 months of either PTC or usual care. PTC will consist of five weekly sessions and a 1-month follow-up session, during which participants will learn strategies for reducing stress. Neuroimmune and quality of life data will be collected at study start and at the end of the study.

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Female

Criteria

Inclusion Criteria:

• Stage I, II, or III cervical cancer for at 3 months and fewer than 15 months prior to enrollment
• Have completed treatment for cervical cancer
• Fluency in English or Spanish as a primary language
• Access to a telephone

Exclusion Criteria:

• Stage IV cervical cancer
• Previous treatment with a biological response modifier
• Prior immunotherapy within 4 weeks of study entry
• Use of investigational drugs within 30 days of study entry
• Use of corticosteroids or immune suppression therapy
• Metastatic disease or ongoing treatment
• Serious acute or chronic illnesses