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Binswanger's Disease Information Page - Article


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Dementia

Senility




Article: Binswanger's Disease Information Page

What is Binswanger's Disease?


Binswanger's disease, sometimes referred to as subcortical dementia, is a rare form of dementia characterized by cerebrovascular lesions in the deep white-matter of the brain, loss of memory and cognition, and mood changes. Patients usually show signs of abnormal blood pressure, stroke, blood abnormalities, disease of the large blood vessels in the neck, and disease of the heart valves. Other prominent features of the disease include urinary incontinence, difficulty walking, clumsiness, slowness of conduct, lack of facial expression, and speech difficulty. These symptoms, which tend to begin after the age of 60, are not always present in all patients and may sometimes appear only as a passing phase.

Is there any treatment?

There is no specific course of treatment for Binswanger's disease. Treatment is symptomatic, often involving the use of medications to control high blood pressure, depression, heart arrhythmias and low blood pressure.

What is the prognosis?

Binswanger's disease is a slowly progressive condition for which there is no cure. The disorder is often marked by strokes and partial recovery.

What research is being done?

The NINDS conducts and supports a wide range of research on dementing disorders, and scientists are currently re-evaluating the definitions for certain dementias, including Binswanger's disease/subcortical dementia. The goals of research are to improve the diagnosis of dementias and to find ways to treat and prevent them. The National Institute on Aging and the National Institute of Mental Health also support research related to the dementias.

Select this link to view a list of studies currently seeking patients.

Organizations

Alzheimer's Disease Education and Referral Center (ADEAR)
P.O. Box 8250
Silver Spring, MD   20907-8250
adear@alzheimers.org
http://www.alzheimers.org
Tel: 301-495-3311 800-438-4380
Fax: 301-495-3334

Alzheimer's Association
225 North Michigan Avenue
17th Floor
Chicago, IL   60601-7633
info@alz.org
http://www.alz.org
Tel: 312-335-8700 800-272-3900
Fax: 312-335-1110

American Heart Association
7272 Greenville Avenue
Dallas, TX   75231-4596
inquiries@heart.org
http://www.americanheart.org
Tel: 800-AHA-USA1 (242-8721) 214-373-6300
Fax: 214-369-3685

Family Caregiver Alliance
690 Market Street
Suite 600
San Francisco, CA   94104
info@caregiver.org
http://www.caregiver.org
Tel: 415-434-3388 800-445-8106
Fax: 415-434-3508

National Organization for Rare Disorders (NORD)
P.O. Box 1968
(55 Kenosia Avenue)
Danbury, CT   06813-1968
orphan@rarediseases.org
http://www.rarediseases.org
Tel: 203-744-0100 Voice Mail 800-999-NORD (6673)
Fax: 203-798-2291

National Stroke Association
9707 East Easter Lane
Englewood, CO   80112-3747
info@stroke.org
http://www.stroke.org
Tel: 303-649-9299 800-STROKES (787-6537)
Fax: 303-649-1328


Source: National Institute of Neurological Disorders and Stroke
Cache Date: December 15, 2004

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December 4, 2008



Page Updated: May 11, 2006
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