Gaucher Disease Clinical Trials

• A Study of the Efficacy and Safety of Genz-112638 in Type 1 Gaucher Patients
  ClinicalTrials.gov Identifier: NCT00358150 - Active, not recruiting
  Gaucher Disease, Type 1; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease; Gaucher Disease, Non-Neuronopathic Form
  
• Safety and Efficacy of Cerezyme® Infusions Every 4 Weeks Versus Every 2 Weeks in Type 1 Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00364858 - Active, not recruiting
  Gaucher Disease, Type 1; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease; Gaucher Disease, Non-Neuronopathic Form
  
• International Collaborative Gaucher Group (ICGG) Gaucher Registry
  ClinicalTrials.gov Identifier: NCT00358943 - Recruiting
  Gaucher Disease; Cerebroside Lipidosis Syndrome; Glucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease
  
• Open-Label Extension Study Evaluating Long Term Safety in Patients With Type 1 Gaucher Disease Receiving DRX008A (ERT)
  ClinicalTrials.gov Identifier: NCT00391625 - Active, not recruiting
  Gaucher Disease, Type 1
  
• OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients with Neuronopathic Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00041535 - Active, not recruiting
  Gaucher Disease
  
• A Study to Evaluate and Characterize the Effect of Pharmacological Chemicals on Blood From Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00465062 - Recruiting
  Gaucher Disease
  
• A Phase III Trial to Assess the Safety and Efficacy of Plant Cell Expressed GCD in Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00376168 - Recruiting
  Gaucher Disease
  
• A Study of GA-GCB Enzyme Replacement Therapy in Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00430625 - Recruiting
  Gaucher Disease,Type 1
  
• A Study of AT2101 in Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00446550 - Recruiting
  Gaucher Disease, Type 1
  
• Safety Study of AT2101 in Adult Patients With Type 1 Gaucher Disease Currently Receiving Enzyme Replacement Therapy
  ClinicalTrials.gov Identifier: NCT00433147 - Recruiting
  Gaucher Disease, Type 1
  
• Multicenter Open-Label Study of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imiglucerase
  ClinicalTrials.gov Identifier: NCT00478647 - Recruiting
  Gaucher Disease, Type 1
  
• Nervous System Degeneration in Glycosphingolipid Storage Disorders
  ClinicalTrials.gov Identifier: NCT00029965 - Recruiting
  Gangliosidoses; Gaucher Disease
  
• A Multicenter Study of the Efficacy of Cerezyme in Testing Skeletal Disease in Patients With Type I Gaucher Disease.
  ClinicalTrials.gov Identifier: NCT00365131 - Completed
  Gaucher Disease Type I; Cerebroside Lipidosis Syndrome; Clucocerebrosidase Deficiency Disease; Glucosylceramide Beta-Glucosidase Deficiency Disease; Gaucher Disease, Non-Neuronopathic Form
  
• Oral Miglustat in Adult Patients With Stable Type 1 Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00319046 - Recruiting
  Type 1 Gaucher Disease
  
• Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations
  ClinicalTrials.gov Identifier: NCT00302146 - Recruiting
  Glucocerebrosidase Mutations; Gaucher Disease
  
• A Multicenter, Randomized, Double-Blind, Parallel-Group Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) ERT Compared With Imiglucerase in Type I Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00553631 - Not yet recruiting
  Gaucher Disease, Type 1
  
• Study to Evaluate Blood Cell Lines From Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00351156 - Completed
  Gaucher Disease
  
• Convection-Enhanced Delivery of Glucocerebrosidase to Treat Type 2 Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00244582 - Completed
  Type 2 Gaucher Disease
  
• Phase II Study of Glucocerebrosidase in Patients With Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00004293 - Recruiting
  Gaucher's Disease
  
• PEG-Glucocerebrosidase for the Treatment of Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00001410 - Completed
  Gaucher's Disease
  
• Phase I Single Dose-Escalation Safety Study of Human Glucocerebrosidase (prGCD)
  ClinicalTrials.gov Identifier: NCT00258778 - Completed
  Gaucher Disease
  
• Combination Chemotherapy and Radiation Therapy in Treating Children With Previously Untreated Stage II, Stage III, or Stage IV Hodgkin's Disease
  ClinicalTrials.gov Identifier: NCT00004010 - Active, not recruiting
  stage III childhood Hodgkin's disease; stage IV childhood Hodgkin's disease; childhood lymphocyte predominant Hodgkin's disease; ...
  
• Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease
  ClinicalTrials.gov Identifier: NCT00003421 - Active, not recruiting
  stage II adult Hodgkin's disease; stage III adult Hodgkin's disease; stage IV adult Hodgkin's disease; stage I adult Hodgkin's disease
  
• Radiation Therapy and Chemotherapy in Treating Patients With Hodgkin's Disease
  ClinicalTrials.gov Identifier: NCT00002561 - Active, not recruiting
  adult lymphocyte predominant Hodgkin's disease; adult lymphocyte depletion Hodgkin's disease; adult mixed cellularity Hodgkin's disease; ...
  
• Best Bypass Surgery (BBS) Trial
  ClinicalTrials.gov Identifier: NCT00120991 - Active, not recruiting
  Heart Disease; Cardiovascular Disease
  
• Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hodgkin's Disease
  ClinicalTrials.gov Identifier: NCT00004169 - Active, not recruiting
  recurrent childhood Hodgkin's disease; recurrent adult Hodgkin's disease
  
• Risk Evaluation and Education for Alzheimer's Disease (REVEAL) II
  ClinicalTrials.gov Identifier: NCT00089882 - Active, not recruiting
  Alzheimer Disease
  
• Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study
  ClinicalTrials.gov Identifier: NCT00053599 - Active, not recruiting
  Alzheimer Disease
  
• Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease
  ClinicalTrials.gov Identifier: NCT00002827 - Active, not recruiting
  stage II childhood Hodgkin's disease; stage III childhood Hodgkin's disease; cardiac toxicity; stage I childhood Hodgkin's disease; ...
  
• Randomized Study of Fetal Neurotransplantation for the Treatment of Parkinson's Disease
  ClinicalTrials.gov Identifier: NCT00004844 - Active, not recruiting
  Parkinson Disease
  
• A Randomized Placebo Controlled Study to Show That Rasagiline May Slow Disease Progression for Parkinson's Disease
  ClinicalTrials.gov Identifier: NCT00256204 - Active, not recruiting
  Parkinson's Disease
  
• SONIC: Study of Biologic and Immunomodulator Naïve Patients in Crohn's Disease
  ClinicalTrials.gov Identifier: NCT00094458 - Active, not recruiting
  Crohn's Disease
  
• Trial of Growth Hormone Therapy in Pediatric Crohn's Disease
  ClinicalTrials.gov Identifier: NCT00109473 - Active, not recruiting
  Crohn's Disease
  
• ADNI: Alzheimer's Disease Neuroimaging Initiative
  ClinicalTrials.gov Identifier: NCT00106899 - Active, not recruiting
  Alzheimer's Disease
  
• GTA-Glyceryltriacetate for Canavan Disease
  ClinicalTrials.gov Identifier: NCT00278707 - Active, not recruiting
  Infantile Canavan Disease; Deficiency Disease, Aspartoacylase
  
• Combination Chemotherapy in Treating Patients With Hodgkin's Disease and HIV Infection
  ClinicalTrials.gov Identifier: NCT00003262 - Active, not recruiting
  stage II adult Hodgkin's disease; AIDS-related peripheral/systemic lymphoma; stage III adult Hodgkin's disease; stage IV adult Hodgkin's disease; ...
  
• Stem Cell Transplant for Inborn Errors of Metabolism
  ClinicalTrials.gov Identifier: NCT00176904 - Recruiting
  Adrenoleukodystrophy; Metachromatic Leukodystrophy; Globoid Cell Leukodystrophy; Gaucher’s Disease; Fucosidosis; Wolman Disease; Niemann-Pick Disease; Batten Disease; GM1 Gangliosidosis; Tay Sachs Disease; Sandhoff Disease
  
• Alzheimer's Disease: Therapeutic Potential of Estrogen
  ClinicalTrials.gov Identifier: NCT00066157 - Active, not recruiting
  Alzheimer Disease
  
• Periapical Bone Healing After Apicectomy With and Without Retrograde Root Filling
  ClinicalTrials.gov Identifier: NCT00228280 - Active, not recruiting
  Stomatognathic Disease; Mouth Disease; Periapical Disease; Alveolar Bone Loss
  
• Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy and Pharmacokinetics of Myozyme in Patients with Late-Onset Pompe Disease.
  ClinicalTrials.gov Identifier: NCT00158600 - Active, not recruiting
  Pompe Disease (Late-onset); Glycogen storage disease type II (GSD-II); Acid Maltase Deficiency Disease; Glycogenosis 2
  
• A Phase II Optimization Study of BMS068645 and Sestamibi Planar Imaging
  ClinicalTrials.gov Identifier: NCT00162071 - Active, not recruiting
  Cardiovascular Disease; Ischemic Heart Disease
  
• Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
  ClinicalTrials.gov Identifier: NCT00001476 - Active, not recruiting
  Chronic Granulomatous Disease; Communicable Disease
  
• Effects of an Anti-Inflammatory Drug in Alzheimer's Disease
  ClinicalTrials.gov Identifier: NCT00013650 - Active, not recruiting
  Alzheimer's Disease
  
• Remission in Subjects with Crohn's Disease
  ClinicalTrials.gov Identifier: NCT00055497 - Active, not recruiting
  Crohn's Disease
  
• Long-Term Dopamine Transporter Imaging and Clinical Assessment of Parkinson''s Disease Progression
  ClinicalTrials.gov Identifier: NCT00134784 - Active, not recruiting
  Parkinson''s Disease
  
• A Study of the Safety and Efficacy of Infliximab (Remicade) in Subjects with Fistulizing Crohn''s Disease
  ClinicalTrials.gov Identifier: NCT00207766 - Active, not recruiting
  Crohn Disease
  
• Combination Chemotherapy Given With Radiation Therapy or Radiation Therapy Alone in Treating Patients With Early-Stage Hodgkin's Disease
  ClinicalTrials.gov Identifier: NCT00002987 - Active, not recruiting
  stage II adult Hodgkin's disease; stage I adult Hodgkin's disease
  
• Humanized anti-IL-2 receptor monoclonal antibody in moderate-to-severe ulcerative colitis
  ClinicalTrials.gov Identifier: NCT00073047 - Active, not recruiting
  Ulcerative Colitis; Gastrointestinal Disease; Inflammatory Bowel Disease
  
• Study of Clozapine for the Treatment of Psychosis in Patients with Idiopathic Parkinson's Disease
  ClinicalTrials.gov Identifier: NCT00004826 - Active, not recruiting
  Parkinson Disease
  
• Observational Study of Heart Valve Disease in Patients With Parkinson's Disease Treated With Pergolide
  ClinicalTrials.gov Identifier: NCT00202657 - Active, not recruiting
  Parkinson's Disease; Pergolide
  
• Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
  ClinicalTrials.gov Identifier: NCT00005900 - Active, not recruiting
  I Cell Disease; Fucosidosis; Globoid Cell Leukodystrophy; Adrenoleukodystrophy; Mannosidosis; Niemann-Pick Disease; Pulmonary Complications; ...
  
• Liposomal Tretinoin in Treating Patients With Recurrent or Refractory Hodgkin's Disease
  ClinicalTrials.gov Identifier: NCT00005969 - Active, not recruiting
  recurrent childhood Hodgkin's disease; recurrent adult Hodgkin's disease
  
• Stem Cell Study for Patients with Heart Disease
  ClinicalTrials.gov Identifier: NCT00081913 - Active, not recruiting
  Chest Pain; Myocardial Ischemia; Heart Disease; Coronary Arterial Disease (CAD); Angina
  
• Evaluation of the Combined Use of L-Arginine and Angiogenic Factors in Patients Undergoing Surgery for Severe, Diffuse Coronary Artery Disease
  ClinicalTrials.gov Identifier: NCT00134433 - Active, not recruiting
  Coronary Artery Disease, Diffuse; Coronary Artery Disease, Deemed Inoperable
  
• Replagal Enzyme Replacement Therapy for Children with Fabry Disease
  ClinicalTrials.gov Identifier: NCT00084084 - Active, not recruiting
  Fabry Disease
  
• Anti-Oxidant Treatment of Alzheimer''s Disease
  ClinicalTrials.gov Identifier: NCT00117403 - Active, not recruiting
  Alzheimer''s Disease
  
• Study for the Treatment of Crohn''s Disease with Adacolumn
  ClinicalTrials.gov Identifier: NCT00162942 - Active, not recruiting
  Crohn''s Disease
  
• A Multi-Center, Observational Safety Registry of Subjects with Idiopathic Parkinson''s Disease Previously Treated with Intraputaminal Infusion of Liatermin
  ClinicalTrials.gov Identifier: NCT00148369 - Active, not recruiting
  Idiopathic Parkinson''s Disease
  
• PET Changes in Alzheimer's Disease (AD)
  ClinicalTrials.gov Identifier: NCT00094913 - Active, not recruiting
  Alzheimer Disease
  
• The Depression in Alzheimer's Disease Study (DIADS)
  ClinicalTrials.gov Identifier: NCT00009191 - Active, not recruiting
  Alzheimer Disease; Depression
  
• European Study of 3APS in Mild to Moderate Alzheimer''s Disease Patients
  ClinicalTrials.gov Identifier: NCT00217763 - Active, not recruiting
  Alzheimer''s Disease
  
• RESTORE-IT-Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients With a History of Atherosclerotic Disease
  ClinicalTrials.gov Identifier: NCT00385385 - Recruiting
  Coronary Artery Disease; Cerebrovascular Disease; Peripheral Vascular Disease
  
• Genes and Fibrinolytic Capacity of Human Endothelium
  ClinicalTrials.gov Identifier: NCT00139503 - Active, not recruiting
  Cardiovascular Diseases; Heart Diseases; Thrombosis; Blood Disease; Coronary Disease
  
• EARTH 413: An Open-Label Study to Evaluate the Effectiveness and Safety of Donepezil Hydrochloride (Aricept) in Hispanic Patients With Mild to Moderate Alzheimer''s Disease (AD)
  ClinicalTrials.gov Identifier: NCT00230568 - Active, not recruiting
  Alzheimer''s Disease
  
• Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00072826 - Active, not recruiting
  Sickle Cell Disease
  
• Evaluation of Alzhemed™ in Patients with Mild to Moderate Alzheimer's Disease
  ClinicalTrials.gov Identifier: NCT00088673 - Active, not recruiting
  Alzheimer Disease
  
• Alicaforsen (ISIS 2302) in Patients with Active Crohn's Disease
  ClinicalTrials.gov Identifier: NCT00048295 - Active, not recruiting
  Crohn's Disease
  
• Study of an Investigational Drug for the treatment of Alzheimer's Disease
  ClinicalTrials.gov Identifier: NCT00074529 - Active, not recruiting
  Alzheimer's Disease
  
• A Safety and Efficacy Study of Infliximab (Remicade) in Patients with Moderate to Severe Active Crohn''s Disease
  ClinicalTrials.gov Identifier: NCT00207662 - Active, not recruiting
  Crohn Disease
  
• A Study of the Sense of Smell in Relatives of Parkinson's Disease Patients
  ClinicalTrials.gov Identifier: NCT00096876 - Active, not recruiting
  Parkinson Disease; Parkinsonian Syndrome
  
• MIG-HD: Multicentric Intracerebral Grafting in Huntington’s Disease
  ClinicalTrials.gov Identifier: NCT00190450 - Active, not recruiting
  Huntington Disease
  
• Psychobiology in Inflammatory Bowel Disease(IBD)
  ClinicalTrials.gov Identifier: NCT00248742 - Active, not recruiting
  Ulcerative Colitis and Crohn’s Disease
  
• Computer-Based Training for Mild Alzheimer’s Disease
  ClinicalTrials.gov Identifier: NCT00319891 - Active, not recruiting
  Alzheimer's Disease
  
• Phase I Study of Retrovirally Mediated Transfer of the Human Glucocerebrosidase Gene into Peripheral Blood Stem Cells for Autologous Transplantation in Patients with Type I Gaucher Disease
  ClinicalTrials.gov Identifier: NCT00004294 - Completed
  Gaucher's Disease
  
• Certolizumab in Crohn's Disease Patient With Loss of Response or Intolerance to Infliximab
  ClinicalTrials.gov Identifier: NCT00308581 - Active, not recruiting
  Crohn Disease
  
• Cholesterol and Pharmacogenetic Study
  ClinicalTrials.gov Identifier: NCT00451828 - Active, not recruiting
  Hyperlipidemia; Hypercholesterolemia; Coronary Heart Disease; Cardiovascular Disease
  
• Sirolimus as Secondary Therapy in Treating Patients With Chronic Graft-Versus-Host Disease That Did Not Respond to Previous Systemic Treatment
  ClinicalTrials.gov Identifier: NCT00079183 - Active, not recruiting
  Graft Versus Host Disease
  
• Extension Study to Assess the Safety and Efficacy of Pasireotide in Patients With Cushing's Disease
  ClinicalTrials.gov Identifier: NCT00171951 - Active, not recruiting
  Cushing Disease
  
• Study to Evaluate the Safety and Tolerability of Rasagiline in Advanced Parkinson’s Disease Patients
  ClinicalTrials.gov Identifier: NCT00203164 - Active, not recruiting
  Parkinson's Disease
  
• A Study of the Safety and Efficacy of Inflixiamb (Remicade) in Pediatric Patients With Crohn's Disease
  ClinicalTrials.gov Identifier: NCT00207675 - Active, not recruiting
  Crohn Disease
  
• Efficacy and Safety Study of Zinc Acetate to Treat Wilson's Disease in Japan.
  ClinicalTrials.gov Identifier: NCT00212368 - Active, not recruiting
  Wison's Disease
  
• POETRY: Study of Estrogen Replacement Therapy in Postmenopausal Women With Parkinson’s Disease
  ClinicalTrials.gov Identifier: NCT00234676 - Active, not recruiting
  Parkinson's Disease
  
• Long-Term Administration Study of SND 919 Tablets in Parkinson's Disease
  ClinicalTrials.gov Identifier: NCT00274131 - Active, not recruiting
  Parkinson Disease
  
• A Phase III Study to Evaluate the Use and Safety of CARDIOLITE® in Pediatric Patients with Kawasaki Disease
  ClinicalTrials.gov Identifier: NCT00162032 - Active, not recruiting
  Kawasaki Disease
  
• Visilizumab in Treating Patients With Graft-Versus-Host Disease Following Donor Stem Cell Transplantation
  ClinicalTrials.gov Identifier: NCT00042744 - Active, not recruiting
  Graft Versus Host Disease
  
• Embryonic Dopamine Cell Implants for Parkinson's Disease: A Double-Blind Study
  ClinicalTrials.gov Identifier: NCT00038116 - Active, not recruiting
  Parkinson Disease
  
• Genetic Susceptibility to Cardiovascular Disease in Patients on Kidney Dialysis
  ClinicalTrials.gov Identifier: NCT00340119 - Active, not recruiting
  End Stage Renal Disease; ESRD
  
• Periodontitis and Cardiovascular Events or "PAVE"
  ClinicalTrials.gov Identifier: NCT00066053 - Active, not recruiting
  Cardiovascular Disease; Coronary Heart Disease; Myocardial Infarction; Cerebrovascular Accident
  
• Study of HGF via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia
  ClinicalTrials.gov Identifier: NCT00060892 - Active, not recruiting
  Arterial Occlusive Disease; Peripheral Vascular Disease; Ischemia
  
• Dosing Study of Replagal in Patients with Fabry Disease
  ClinicalTrials.gov Identifier: NCT00068107 - Active, not recruiting
  Fabry Disease
  
• Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients with von Hippel Lindau Disease
  ClinicalTrials.gov Identifier: NCT00005902 - Active, not recruiting
  Hemangioblastoma; Hippel Lindau Disease
  
• Profylactic Antibiotic Treatment of Patients with Chronic Obstructive Lung Disease (COLD)
  ClinicalTrials.gov Identifier: NCT00132860 - Active, not recruiting
  Pulmonary Disease, Chronic Obstructive
  
• Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer’s Disease
  ClinicalTrials.gov Identifier: NCT00257673 - Active, not recruiting
  Alzheimer's Disease
  
• Atomoxetine and Huntington's Disease
  ClinicalTrials.gov Identifier: NCT00368849 - Active, not recruiting
  Huntington Disease; Chorea
  
• Quality of Life in Pediatric Inflammatory Bowel Disease
  ClinicalTrials.gov Identifier: NCT00061737 - Active, not recruiting
  Crohn's Disease; Ulcerative Colitis
  
• Study Evaluating SRA-333 in Mild to Moderate Alzheimer''s Disease (AD)
  ClinicalTrials.gov Identifier: NCT00151333 - Active, not recruiting
  Alzheimer''s Disease
  
• Study Evaluating Lecozotan SR in Mild to Moderate Alzheimer''s Disease (AD)
  ClinicalTrials.gov Identifier: NCT00151398 - Active, not recruiting
  Alzheimer''s Disease
  
• Treatment of Severe Alzheimer's Disease: Evaluation of Efficacy and Safety of Galantamine Hydrobromide in a Controlled Study
  ClinicalTrials.gov Identifier: NCT00216593 - Active, not recruiting
  Dementia; Alzheimer Disease
  
• Safety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease Who Completed Protocol CL0600-008
  ClinicalTrials.gov Identifier: NCT00308438 - Active, not recruiting
  Crohn Disease
  
• Compassionate Use of Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Gastrointestinal Tract
  ClinicalTrials.gov Identifier: NCT00055666 - Active, not recruiting
  Graft Versus Host Disease