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Medical Education & Training |
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Clinical Trial: Functional Circuit Training in Older Adults with Congestive Heart Failure
This study is currently recruiting patients.
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Purpose
The goal of this study is to determine the effect of a functional circuit training program as compared to standard cardiac rehabilitation or control exercise in improving physical function and activity.
| Condition | Treatment or Intervention |
|---|---|
| Heart Failure, Congestive | Procedure: Circuit Training Procedure: Cardiac Rehabilitation Procedure: Flexibility and toning |
MedlinePlus related topics: Heart Failure
Study Type: Interventional
Study Design: Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Efficacy Study
Study start: October 2003; Expected completion: December 2008
In older (65 years of age or older) patients with congestive heart failure, we propose to:
1. Assess: a) Peak aerobic capacity (peak VO2) during a monitored, standardized treadmill test; b) Oxygen uptake kinetics and heart rate during a standardized submaximal treadmill test; c) Performance on a set of functional mobility tasks; d) Self-report of physical disability and difficulty in performing daily tasks, and physical activity.
2. Conduct a 12-week randomized controlled trial, comparing changes in these assessed measures in patients randomized to three different groups: 1) standard cardiac rehabilitation using bicycle exercise; 2) group functional circuit training focusing on exercises that involve functional mobility tasks and a home-activities exercise component; 3) a chair-based, flexibility and "toning " (low level resistance) group control exercise.
3. Reassess all groups after an additional 12 weeks in the measures identified above to identify how well the three groups maintain their function.
4. Examine the mechanisms underlying change in functional mobility performance and self-reported function as a result of the interventions
Primary hypothesis 1: Compared to chair-based exercise controls at the end of week 12, both the cardiac rehabilitation and functional circuit training groups will show improvements in measures of peak aerobic capacity, submaximal oxygen uptake kinetics, functional mobility performance, and self-reported function.
Primary hypothesis 2: Compared to the other two groups that are given exercise instructions only, the functional circuit training group, who continue their home activities exercise program, show less decline by week 24 in measures of peak aerobic capacity, submaximal oxygen uptake kinetics, functional mobility performance, and self-reported function.
Secondary hypothesis: Measures of submaximal oxygen uptake kinetics are better predictors of changes in functional mobility performance and self-reported function than peak aerobic capacity, muscle strength, joint range of motion, balance, and behavioral factors (such as depression).
Eligibility
Ages Eligible for Study: 60 Years and above, Genders Eligible for Study: Both
Criteria
Inclusion Criteria:
- Congestive Heart Failure
Location and Contact Information
Michigan
VA Ann Arbor Healthcare System, Ann Arbor, Michigan, 48105, United States; Recruiting
Neil Alexander, M.D., Principal Investigator
More Information
Record last reviewed: April 2005
Last Updated: April 14, 2005
Record first received: April 14, 2005
ClinicalTrials.gov Identifier: NCT00108147
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-05-03
Source: ClinicalTrials.gov
Cache Date: May 4, 2005
Resources
- 4th Year Medical Student Electives in Women's Health (Women's Health Program, University of Cincinnati College of Medicine)
- Directory of Residency and Fellowship Programs in Women's Health (Office on Women's Health, HHS)

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