Not Signed In -
Radiation Therapy |
Brachytherapy; Radiofrequency Ablation; Radiosurgery |
Clinical Trial: Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer
This study is currently recruiting patients.
Purpose
RATIONALE: Moving a salivary gland out of the area that will undergo radiation therapy may protect the gland from side effects of radiation therapy and may prevent xerostomia (dry mouth).
PURPOSE: Phase II trial to study the effectiveness of salivary gland surgery in preventing xerostomia in patients who are undergoing radiation therapy for head and neck cancer.
| Condition | Treatment or Intervention | Phase |
|---|---|---|
| Hypopharyngeal Cancer Laryngeal Cancer metastatic squamous neck cancer with occult primary oral complications of chemotherapy and head and neck radiation Oropharyngeal Cancer | Procedure: conventional surgery Procedure: radiation therapy Procedure: radioprotection Procedure: supportive care/therapy Procedure: surgery | Phase II |
MedlinePlus related topics: Cancer; Cancer Alternative Therapy; Head and Neck Cancer
Study Type: Interventional
Study Design: Treatment
Official Title: Phase II Study of Salivary Gland Transfer Surgery Prior to Radiotherapy for the Prevention of Radiation-Induced Xerostomia in Patients With Head and Neck Cancer
Further Study Details:
OBJECTIVES:
- Determine the reproducibility of the surgical technique of submandibular salivary gland transfer in patients with head and neck cancer.
- Determine the rate and severity of radiation-induced xerostomia after this surgery in these patients.
- Determine the pattern of recurrence, disease-free survival, and overall survival of patients treated with this surgery followed by radiotherapy.
- Determine the quality of life of patients treated with this regimen.
OUTLINE: This is a multicenter study.
Patients undergo surgical transfer of the submandibular salivary gland to the submental space.
Within 4-6 weeks after surgery, patients undergo radiotherapy once daily, 5 days a week for 5 ½ to 7 weeks in the absence of disease progression or unacceptable toxicity.
Salivary scans are performed before surgery, at 2-3 weeks after surgery, and then at 6 months from the start of radiotherapy.
Quality of life is assessed at baseline and at 3, 6, and 12 months from the start of radiotherapy.
Patients are followed every 3 months for 2 years and then every 6 months for 3 years.
PROJECTED ACCRUAL: A total of 11-48 patients will be accrued for this study within 1.6 years.
Eligibility
Ages Eligible for Study: 18 Years - 80 Years, Genders Eligible for Study: Both
Criteria
DISEASE CHARACTERISTICS:
- One of the following diagnoses:
- Histologically confirmed, previously untreated squamous cell carcinoma of the oropharynx, hypopharynx, or larynx
- Head and neck cancer of unknown primary with unilateral metastases to the neck nodes
- No N3 disease
- No carcinoma of the oral cavity or nasopharynx
- No bilateral neck node involvement
- No pre-epiglottic space involvement
- No involvement of level 1 nodes on either side of the neck
- No salivary gland malignancy
- No recurrent disease
PATIENT CHARACTERISTICS: Age
- 18 to 80
Performance status
- Zubrod 0-1
Life expectancy
- Not specified
Hematopoietic
- Hemoglobin at least 10 g/dL
Hepatic
- Not specified
Renal
- Not specified
Other
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use effective contraception
- No salivary gland disease (e.g., Sjögren's syndrome)
- No other malignancy within the past 3 years except basal cell or squamous cell skin cancer
PRIOR CONCURRENT THERAPY: Biologic therapy
- Not specified
Chemotherapy
- More than 3 years since prior chemotherapy
- No prior or concurrent neoadjuvant chemotherapy
- Concurrent adjuvant chemoradiotherapy (in addition to study radiotherapy) allowed
Endocrine therapy
- Not specified
Radiotherapy
- See Chemotherapy
- No prior radiotherapy to the head and neck
- No concurrent intensity-modulated radiotherapy
Surgery
- Not specified
Other
- No concurrent cholinergic drugs
- No concurrent anti-cholinergic drugs
- No concurrent tricyclic drugs
- No concurrent prophylactic amifostine or pilocarpine during and for at least 3 months after completion of study radiotherapy
Location and Contact Information
Alabama
Comprehensive Cancer Institute, Huntsville, Alabama, 35801, United States; Recruiting
Noel C. Estopinal, MD, FACRO 256-265-6590
DCH Cancer Treatment Center, Tuscaloosa, Alabama, 35401, United States; Recruiting
Melanie D. Graham, MD 205-759-7800
MBCCOP - Gulf Coast, Mobile, Alabama, 36607, United States; Recruiting
John Ronald Russell, MD 251-435-5568
Montgomery Cancer Center, Montgomery, Alabama, 36106-3657, United States; Recruiting
Robert Lee Franklin, MD 334-273-7000
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, 35294-3300, United States; Recruiting
Ruby F. Meredith, MD, PhD 205-934-4763
Arizona
Foundation for Cancer Research and Education, Phoenix, Arizona, 85013, United States; Recruiting
David G. Brachman, MD, FACRO 602-274-4484
California
California Cancer Center - Woodward Park Office, Fresno, California, 93720, United States; Recruiting
Bruce C. McAllister, MD 559-447-4050
CCOP - Bay Area Tumor Institute, Oakland, California, 94609-3305, United States; Recruiting
Brenda M. Shank, MD, PhD 510-456-8570
CCOP - Santa Rosa Memorial Hospital, Santa Rosa, California, 95403, United States; Recruiting
Jay Samuel Joseph, MD 707-525-1150
City of Hope Comprehensive Cancer Center, Duarte, California, 91010-3000, United States; Recruiting
Clinical Trials Office - New Patient Services 800-826-4673 becomingapatient@coh.org
General Robert Huyser Cancer Center at David Grant Medical Center, Travis Air Force Base, California, 94535, United States; Recruiting
Roland E. Engel, MD 707-423-7691
Huntington Cancer Center at Huntington Hospital, Pasadena, California, 91105, United States; Recruiting
Ruth C. Williamson, MD 626-535-2421
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, 90095-1714, United States; Recruiting
H. Rodney Withers, MD 310-825-8278
Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda, California, 92354, United States; Recruiting
David A. Bush, MD 909-824-4243 dbush@dominion.llumc.edu
Mount Diablo Regional Cancer Center, Concord, California, 94524-4110, United States; Recruiting
Daniel M. Chinn, MD 925-674-2521
Naval Medical Center - San Diego, San Diego, California, 92134-3202, United States; Recruiting
Thomas S. Chung, MD 619-532-7274
O'Connor Hospital, San Jose, California, 95128, United States; Recruiting
Constance Rainer Bowie, MD 408-947-2995
Providence Saint Joseph Medical Center - Burbank, Burbank, California, 91505, United States; Recruiting
Nancy A. Ellerbroek, MD 818-898-4410
Radiation Medical Group, Incorporated, San Diego, California, 92101, United States; Recruiting
Donald B. Fuller, MD 619-230-0400 dfuller@rmgmed.com
Radiation Oncology Centers - Sacramento, Sacramento, California, 95815, United States; Recruiting
Christopher Jones, MD 916-646-6600
Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center, Pomona, California, 91767, United States; Recruiting
Yallapragada S. Rao, MD 909-865-9890
Saint Agnes Cancer Center, Fresno, California, 93720, United States; Recruiting
Madhu Joseph John, MD, FACR, FACRO 209-450-5500
St. Joseph's Regional Cancer Center, Stockton, California, 95204, United States; Recruiting
Henry Y.T. Wong, MD 209-467-6560 hytwong@chw.edu
Sutter Health Western Division Cancer Research Group, Greenbrae, California, 94904, United States; Recruiting
David H. Irwin, MD 510-204-2866
Torrance Memorial Medical Center, Torrance, California, 90505, United States; Recruiting
Thyra Endicott, MD 310-517-4750 thyra.endicott@tmmc.com
UCSF Comprehensive Cancer Center, San Francisco, California, 94115, United States; Recruiting
Mack Roach, MD 415-353-7175
USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, 90033-0804, United States; Recruiting
Oscar E. Streeter, MD 323-865-3084
Veterans Affairs Medical Center - Long Beach, Long Beach, California, 90822, United States; Recruiting
Samar H. Azawi, MD 562-494-5606 samar.azawi@med.va.gov
Colorado
Memorial Hospital Cancer Center, Colorado Springs, Colorado, 80909, United States; Recruiting
Mark Bernard Hazuka, MD 719-365-6800 mark.hazuka@memhospcs.org
St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center, Grand Junction, Colorado, 81502-1628, United States; Recruiting
Douglas B. Rock, MD 970-244-2442
University of Colorado Cancer Center at University of Colorado Health Sciences Center, Denver, Colorado, 80010, United States; Recruiting
Rachel A. Rabinovitch, MD 720-848-0116 rachel.rabinovitch@uchsc.edu
Connecticut
Hospital of Saint Raphael, New Haven, Connecticut, 06511, United States; Recruiting
Joseph G. Cardinale, MD 203-789-3131
Yale Comprehensive Cancer Center, New Haven, Connecticut, 06520-8040, United States; Recruiting
Jonathan P.S. Knisely, MD, FRCPC 203-785-5702 jonathan.knisely@yale.edu
Delaware
CCOP - Christiana Care Health Services, Newark, Delaware, 19713, United States; Recruiting
Christopher D. Koprowski, MD 302-733-1830
District of Columbia
Sibley Memorial Hospital, Washington, District of Columbia, 20016, United States; Recruiting
Gregory S. Sibley, MD 202-537-4787 gsibley@sibley.org
Florida
21st Century Oncology - Fort Myers, Fort Myers, Florida, 33901-8082, United States; Recruiting
Michael Joseph Katin, MD, FACP, FACR, FACRO 239-936-0380 mjkatin@rtsx.com
Baptist-South Miami Regional Cancer Program, Miami, Florida, 33176-2197, United States; Recruiting
Andre A. Abitbol, MD 786-596-6566 andrea@baptisthealth.net
Bay Medical Center, Panama City, Florida, 32401, United States; Recruiting
David B. Hurst, MD 850-747-6972 dhurst@baymedical.org
CCOP - Mount Sinai Medical Center, Miami Beach, Florida, 33140, United States; Recruiting
Michael A. Samuels, MD 305-535-3400 MSamuels@Salick.com
Florida Radiation Oncology Group, Jacksonville, Florida, 32207, United States; Recruiting
Douglas W. Johnson, MD 904-202-7020 djohn005@bmcjax.com
Gulf Coast Cancer Treatment Center, Panama City, Florida, 32405-4587, United States; Recruiting
R. Charles Nichols, MD 850-763-0036 Nicholsmd@aol.com
H. Lee Moffitt Cancer Center and Research Institute at University of South Florida, Tampa, Florida, 33612-9497, United States; Recruiting
Andy M. Trotti, MD 813-972-8424 trotti@moffitt.usf.edu
Holmes Regional Medical Center, Melbourne, Florida, 32901-3276, United States; Recruiting
David L. Grisell, DO 321-434-7179 david.grisell@health-first.org
Sarasota Radiation and Medical Oncology Center, Sarasota, Florida, 34233, United States; Recruiting
W. Jackson Dickens, MD, FACRO 941-924-8700
Tallahassee Memorial Hospital, Tallahassee, Florida, 32308, United States; Recruiting
Timothy W. Bolek, MD 850-431-5255
University of Florida Shands Cancer Center, Gainesville, Florida, 32610-0385, United States; Recruiting
William M. Mendenhall, MD 352-265-0287
University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, 33136, United States; Recruiting
Arnold Markoe, MD, ScD 305-243-4319 amarkoe@med.miami.edu
Georgia
CCOP - Atlanta Regional, Atlanta, Georgia, 30342-1701, United States; Recruiting
Thomas E. Seay, MD, PhD 404-851-2340
John B. Amos Community Cancer Center, Columbus, Georgia, 31904, United States; Recruiting
Douglas F. Ciuba, MD 706-571-1050
Regional Radiation Oncology Center at Rome, Rome, Georgia, 30165, United States; Recruiting
Matt P. Mumber, MD 706-234-1400 mmumber@rrocrome.com
Winship Cancer Institute of Emory University, Atlanta, Georgia, 30322, United States; Recruiting
Jerome C. Landry, MD 404-778-5180
Hawaii
MBCCOP - Hawaii, Honolulu, Hawaii, 96813, United States; Recruiting
Paul A. DeMare, MD, FACR 808-586-2979
Illinois
Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood, Illinois, 60153, United States; Recruiting
Edward Melian, MD 708-216-1588 emelian@lumc.edu
CCOP - Central Illinois, Decatur, Illinois, 62526, United States; Recruiting
James L. Wade, MD 217-876-6617 jlwade3@sbcglobal.net
Ingalls Cancer Care Center at Ingalls Memorial Hospital, Harvey, Illinois, 60426, United States; Recruiting
Robert E. Share, MD 708-915-6620 Rshare@ingalls.org
Lutheran General Cancer Care Center, Park Ridge, Illinois, 60068, United States; Recruiting
John Han-Chih Chang, MD 847-723-8030 jchang@chicagocancer.org
Methodist Medical Center of Illinois, Peoria, Illinois, 61636, United States; Recruiting
Revathi Swaminathan, MD 309-672-5700 rswaminathan@mmci.org
Northwest Community Hospital, Arlington Heights, Illinois, 60005, United States; Recruiting
Arnold M. Herskovic, MD 847-618-6576 arnoldh134@aol.com
Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois, 60611-3013, United States; Recruiting
William Small, MD 312-926-6810 w-small@northwestern.edu
Indiana
Bloomington Hospital, Bloomington, Indiana, 47402, United States; Recruiting
David Y. Lee, MD 812-353-9633 dlee@bloomhealth.org
Cancer Center at Ball Memorial Hospital, Muncie, Indiana, 47303-3499, United States; Recruiting
Anthony S. Tilmans, MD 765-747-3827
CCOP - Northern Indiana CR Consortium, South Bend, Indiana, 46601, United States; Recruiting
David A. Hornback, MD 574-647-7370
Community Regional Cancer Care, Indianapolis, Indiana, 46219, United States; Recruiting
Morgan E. Tharp, MD 317-355-5347
Methodist Cancer Center at Methodist Hospital, Indianapolis, Indiana, 46206-1367, United States; Recruiting
Peter G. Garrett, MD 317-962-3172
Oncology Institute of Greater Lafayette, Lafayette, Indiana, 47904, United States; Recruiting
Li-Fen Lien Chang, MD, PhD 765-448-7557 changl@arnett.com
St. John's Cancer Center at St. John's Medical Center, Anderson, Indiana, 46016, United States; Recruiting
James E. Currier, MD 765-649-2511
Veterans Affairs Medical Center - Indianapolis (Roudebush), Indianapolis, Indiana, 46202, United States; Recruiting
Ronald McGarry, MD 317-274-2525 ron.mcgarry@iupui.edu
Iowa
Wendt Regional Cancer Center at Finley Hospital, Dubuque, Iowa, 52001, United States; Recruiting
James R. Baer, MD 563-589-2468
Kentucky
Cancer Center at Lexington Clinic, Lexington, Kentucky, 40504, United States; Recruiting
Mark L. Sobczak, MD 859-258-6505 msobc@lexclin.com
Central Baptist Hospital, Lexington, Kentucky, 40503, United States; Recruiting
Alan Beckman, MD 859-260-6460 abeckman@bhsi.com
Esther Marie Hatton Cancer Care Center at St. Elizabeth Medical Center, Edgewood, Kentucky, 41017, United States; Recruiting
Michael A. Cross, MD 859-344-2238
James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky, 40202, United States; Recruiting
Kristie Jones Paris, MD 502-852-7171
Louisville Radiation Oncology Center at Caritas Regional Cancer Center, Louisville, Kentucky, 40215, United States; Recruiting
Mark R. Jones, MD 502-363-3100 raddoc7@bellsouth.net
Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington, Kentucky, 40536-0293, United States; Recruiting
Mohammed M. Mohiuddin, MD 859-323-6489 mohmohi@pop.uky.edu
Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County, Madisonville, Kentucky, 42431, United States; Recruiting
Satish J. Shah, MD 270-825-5800 sshah@trover.org
Louisiana
CCOP - Ochsner, New Orleans, Louisiana, 70121, United States; Recruiting
Carl G. Kardinal, MD 504-842-3910
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, 70809-3482, United States; Recruiting
Kenneth K. Lo, MD 225-767-0847
MBCCOP - LSU Health Sciences Center, New Orleans, Louisiana, 70112, United States; Recruiting
Jill Gilbert, MD 504-568-5613 jgilbe@lsuhsc.edu
Tulane Cancer Center at Tulane University Hospital and Clinic, New Orleans, Louisiana, 70112-2699, United States; Recruiting
Ellen L. Zakris, MD 504-988-1070 ezakris@tulane.edu
Maine
Maine Medical Center - Bramhall Campus, Portland, Maine, 04102, United States; Recruiting
John R. Mullen, MD 207-871-2276 mullej@spectrummg.com
Maryland
Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore, Maryland, 21215, United States; Recruiting
Mark Joel Brenner, MD, FACR 410-601-5689 mbrenner@lifebridgehealth.org
Cancer Center at Greater Baltimore Medical Center, Baltimore, Maryland, 21204, United States; Recruiting
Robert K. Brookland, MD 443-849-2540
DeCesaris Cancer Institute at Anne Arundel Medical Center, Annapolis, Maryland, 21401, United States; Recruiting
Angel E. Torano, MD 443-481-5800
Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, 21201, United States; Recruiting
Mohan Suntharalingam, MD 410-328-2331 msunthar@umm.edu
Harbor Hospital Center, Baltimore, Maryland, 21215-1290, United States; Recruiting
Jack J. Hong, MD 410-355-0868 jack.j.hong@medstar.net
Peninsula Regional Medical Center, Salisbury, Maryland, 21801, United States; Recruiting
Scott A. Edwards, MD 410-543-7000 scott.edwards@peninsula.org
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, 21231-2410, United States; Recruiting
Ding-Jen Lee, MD 410-955-8062 leedj@jhmi.edu
St. Agnes Cancer Center, Baltimore, Maryland, 21229, United States; Recruiting
Richard S. Hudes, MD 410-368-2965 rhudes@stagnes.org
Massachusetts
Cancer Research Center at Boston Medical Center, Boston, Massachusetts, 02118, United States; Recruiting
Steven Lane, MD 617-638-7070
Cape Cod Hospital, Hyannis, Massachusetts, 02601, United States; Recruiting
Martin Ivan Holzman, MD 508-862-5309 mholzman@capecodhealth.org
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, 02114, United States; Recruiting
William U. Shipley, MD, FACR 617-726-8146
NSMC Cancer Center - Peabody, Peabody, Massachusetts, 01960, United States; Recruiting
Eric Taylor Weber, MD 978-977-9400
Veterans Affairs Medical Center - Boston (Jamaica Plain), Jamaica Plain, Massachusetts, 02130, United States; Recruiting
Richard H. Matthews, MD, PhD 617-232-9500, ext. 5628
Michigan
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, 48201, United States; Recruiting
Harold E. Kim, MD 313-966-0556 kimh@kci.wayne.edu
CCOP - Beaumont, Royal Oak, Michigan, 48073-6769, United States; Recruiting
John M. Robertson, MD 248-551-7038
CCOP - Kalamazoo, Kalamazoo, Michigan, 49007-3731, United States; Recruiting
Raymond Sterling Lord, MD 269-373-7488 rlord@wmcc.org
CCOP - Michigan Cancer Research Consortium, Ann Arbor, Michigan, 48106, United States; Recruiting
Miljenko V. Pilepich, MD 877-590-5995
Great Lakes Cancer Institute at McLaren Regional Medical Center, Flint, Michigan, 48532-3685, United States; Recruiting
Hesham E. Gayar, MD 810-342-3800 hgayar@aol.com
Josephine Ford Cancer Center at Henry Ford Health System, Detroit, Michigan, 48202, United States; Recruiting
Munther Isa Ajlouni, MD 313-916-1026 majloun1@hfhs.org
MidMichigan Medical Center - Midland, Midland, Michigan, 48670, United States; Recruiting
Paul G. Kocheril, MD 989-839-3450
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, 48109-0010, United States; Recruiting
Howard Mark Sandler, MD 734-936-9338 hsandler@umich.edu
Upper Michigan Cancer Center at Marquette General Hospital, Marquette, Michigan, 49855, United States; Recruiting
Paul O. Thieme, DO 906-225-3102
William Beaumont Hospital - Royal Oak, Royal Oak, Michigan, 48073, United States; Recruiting
John M. Robertson, MD 248-551-7038 jrobertson@beaumont.edu
William Beaumont Hospital - Troy, Troy, Michigan, 48085, United States; Recruiting
Richard C. Matter, MD 248-964-6156
Minnesota
CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, 55416, United States; Recruiting
Paul Sperduto, MD 952-442-6000
Fairview University Medical Center - University Campus, Minneapolis, Minnesota, 55455, United States; Recruiting
Chung K. Lee, MD 612-273-6700 leexx006@umn.edu
Mayo Clinic Cancer Center, Rochester, Minnesota, 55905-0001, United States; Recruiting
Michael G. Haddock, MD 507-284-2511
Missouri
CCOP - Cancer Research for the Ozarks, Springfield, Missouri, 65807, United States; Recruiting
John W. Clouse, MD 417-269-4520
CCOP - Kansas City, Kansas City, Missouri, 64131, United States; Recruiting
William T. Stephenson, MD 816-823-0555
Ellis Fischel Cancer Center at University of Missouri - Columbia, Columbia, Missouri, 65203, United States; Recruiting
Mark P. Bryer, MD 573-442-5525
Saint Louis University Cancer Center, Saint Louis, Missouri, 63110-0250, United States; Recruiting
Oscar D. Norton, MD 314-577-8815
Siteman Cancer Center at Barnes-Jewish Hospital, St. Louis, Missouri, 63110, United States; Recruiting
Jeff M. Michalski, MD 314-747-7222 michalski@radonc.wustl.edu
Montana
CCOP - Montana Cancer Consortium, Billings, Montana, 59101, United States; Recruiting
Robert D. Pfeffer, MD 406-259-2245
Nebraska
CCOP - Missouri Valley Cancer Consortium, Omaha, Nebraska, 68106, United States; Recruiting
Patrick J. McKenna, MD 402-991-8070
Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha, Omaha, Nebraska, 68114-4199, United States; Recruiting
James A. Wheeler, MD 402-354-4104 jwheele@nmhs.org
UNMC Eppley Cancer Center at the University of Nebraska Medical Center, Omaha, Nebraska, 68198-7521, United States; Recruiting
Robert Bruce Thompson, MD 402-559-3848
Nevada
CCOP - Southern Nevada Cancer Research Foundation, Las Vegas, Nevada, 89106, United States; Recruiting
Raul T. Meoz-Mendez, MD, FACR 702-384-0013
New Hampshire
Elliot Regional Cancer Center, Manchester, New Hampshire, 03103, United States; Recruiting
Andrea McKee, MD 603-663-1800
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, 03756-0002, United States; Recruiting
Eugen B. Hug, MD 603-650-6600 eugen.hug@hitchcock.org
New Jersey
Associated Radiologists, P.A. at Warren Radiation Therapy Center, Warren, New Jersey, 07059, United States; Recruiting
Laura R. Bond, MD 908-769-5999
Atlantic City Medical Center - Mainland Division, Pomona, New Jersey, 08240, United States; Recruiting
Jorge F. Cassir, MD 609-652-3417
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick, New Jersey, 08903, United States; Recruiting
David T. Marshall, MD 732-235-8590
Community Medical Center, Toms River, New Jersey, 08755, United States; Recruiting
Bong M. Chang, MD 732-557-8148 BChang@sbhcs.com
Fox Chase Cancer Center at St. Francis Medical Center, Trenton, New Jersey, 08629, United States; Recruiting
Jo Ann Chalal, MD 609-599-5179 Jchalalm.d@che-east.org
Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital - Marlton, Mount Holly, New Jersey, 08060, United States; Recruiting
Lemuel S. Ariaratnam, MD 609-261-7074 lariaratnam@virtua.org
John F. Kennedy Medical Center, Edison, New Jersey, 08818, United States; Recruiting
Mark S. Macher, MD 732-321-7167 mmacher@solarishs.org
Monmouth Medical Center, Long Branch, New Jersey, 07740-6395, United States; Recruiting
Sang Sim 732-923-6575
Newark Beth Israel Medical Center, Newark, New Jersey, 07112, United States; Recruiting
Robert Ivker, DO 973-926-7320 rivker@sbhcs.com
South Jersey Regional Cancer Center, Millville, New Jersey, 08332, United States; Recruiting
Joseph W. Fanelle, MD 856-293-2910 fanellej@sjhs.com
University Medical Center of Princeton, Princeton, New Jersey, 08540, United States; Recruiting
Robert Michael Cardinale, MD 609-497-4304
Valley Hospital - Ridgewood, Ridgewood, New Jersey, 07450, United States; Recruiting
David Robert Greenblatt, MD 201-447-8220 dgreenb@valleyhealth.com
Veterans Affairs Medical Center - East Orange, East Orange, New Jersey, 07018, United States; Recruiting
Basil S. Kasimis, MD, DSc 973-676-1000 ext. 7095 Basil.Kasimis@med.va.gov
New Mexico
Radiation Oncology Associates of Albuquerque, Albuquerque, New Mexico, 87109, United States; Recruiting
Paul A. Anthony, MD 505-727-7900
New York
Beth Israel Medical Center - Philipps Ambulatory Care Center, New York, New York, 10003, United States; Recruiting
Manjeet Chadha, MD 212-844-8042 mchadha@bethisraelny.org
CCOP - North Shore University Hospital, Manhasset, New York, 11030, United States; Recruiting
Sophie S. Turner, MD, FACR 516-562-8900
CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C., East Syracuse, New York, 13057, United States; Recruiting
N. F. Mariados, MD 315-472-7504
Champlain Valley Physicians Hospital Medical Center, Plattsburgh, New York, 12901-1490, United States; Recruiting
Anthony Vaccaro, MD 518-562-7120 drv@adkradiation.com
Finger Lakes Radiation Oncology Center, Clifton Springs, New York, 14432, United States; Recruiting
Sidney H. Sobel, MD, FACR 315-462-5711
Herbert Irving Comprehensive Cancer Center at Columbia University, New York, New York, 10032, United States; Recruiting
Peter B. Schiff, MD, PhD 212-305-8096
James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester, New York, 14642, United States; Recruiting
Paul Okunieff, MD 585-275-5575 paul_okunieff@urmc.rochester.edu
Lourdes Regional Cancer Center, Binghamton, New York, 13905, United States; Recruiting
Michael Fallon, MD 607-798-5111
Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, United States; Recruiting
Bruce David Minsky, MD 212-639-6817 minskyb@.mskcc.org
New York Methodist Hospital, Brooklyn, New York, 11215-3609, United States; Recruiting
Sameer Rafla-Demetrious, MD, PhD, FRCR, FACR, FRSM 718-780-3677 sar9003@nyp.org
North Shore Radiation Oncology, Setauket, New York, 11733, United States; Recruiting
Martin J. Silverstein, MD 631-246-5860
Riverhill Radiation Oncology, Yonkers, New York, 10701, United States; Recruiting
Arthur D. Brimberg, MD 914-969-1600 abrimberg@rtsx.com
SUNY Downstate Medical Center, Brooklyn, New York, 11203, United States; Recruiting
Marvin Rotman, MD 718-270-2181 mrotman@downstate.edu
SUNY Upstate Medical University Hospital, Syracuse, New York, 13210, United States; Recruiting
Chung-Taik Chung, MD 315-464-5276 chungc@upstate.edu
North Carolina
Batte Cancer Center at Northeast Medical Center, Concord, North Carolina, 28025, United States; Recruiting
Scott P. Lankford, MD 704-783-1577
CCOP - Southeast Cancer Control Consortium, Goldsboro, North Carolina, 27534-9479, United States; Recruiting
James N. Atkins, MD 336-777-3088
Comprehensive Cancer Center at Wake Forest University, Winston Salem, North Carolina, 27157-1082, United States; Recruiting
Kathryn McConnell Greven, MD 336-716-4464
Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital, Greenville, North Carolina, 27835-6028, United States; Recruiting
Kalika P. Sarma, MD 252-744-2900
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill, North Carolina, 27599-7295, United States; Recruiting
Lav K. Goyal, MD 919-966-7700 lav-goyal@med.unc.edu
North Dakota
Trinity Cancer Care Center, Minot, North Dakota, 58701, United States; Recruiting
Kevin Basil Collins, MD 701-857-3535 kevin.collins@trinityhealth.org
Ohio
Akron City Hospital at Summa Health System, Akron, Ohio, 44304, United States; Recruiting
William F. Demas, MD 330-375-3557 demasw@summa-health.org
Akron General's McDowell Cancer Center, Akron, Ohio, 44302, United States; Recruiting
Mitchell Lee Fromm, MD 330-344-6448 mfromm@agmc.org
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University, Columbus, Ohio, 43210-1240, United States; Recruiting
Reinhard A. Gahbauer, MD 614-293-8415 gahbauer.1@osu.edu
Cancer Center at Christ Hospital, Cincinnati, Ohio, 45219, United States; Recruiting
Ralph J. Wright, MD 513-585-2734
CCOP - Columbus, Columbus, Ohio, 43206, United States; Recruiting
Lawrence B. Berk, MD, PhD 614-566-9506
CCOP - Dayton, Dayton, Ohio, 45429, United States; Recruiting
Howard M. Gross, MD 937-832-1093
CCOP - Toledo Community Hospital, Toledo, Ohio, 43623-3456, United States; Recruiting
Paul L. Schaefer, MD 419-843-6147
Charles M. Barrett Cancer Center at University Hospital, Cincinnati, Ohio, 45219, United States; Recruiting
Kevin P. Redmond, MD 513-584-9089 redmonkp@healthall.com
Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, 44195, United States; Recruiting
John H. Suh, MD 216-444-5574 suhj@ccf.org
Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio, 44106-5065, United States; Recruiting
Adir Ludin, MD 216-844-5432
Parma Community General Hospital, Parma, Ohio, 44129, United States; Recruiting
Anthony Mastroianni, MD, JD 440-743-4749
Oklahoma
CCOP - Oklahoma, Tulsa, Oklahoma, 74136, United States; Recruiting
Robert G. Swanson, MD 918-494-1585 rgswanson@saintfrancis.com
Frank C. Love Cancer Institute at St. Anthony Hospital, Oklahoma City, Oklahoma, 73102, United States; Recruiting
Marianne M. Young, MD 405-272-7311
LaFortune Cancer Center at St. John Health System, Tulsa, Oklahoma, 74104, United States; Recruiting
Diane Heaton, MD 918-744-2071 dheaton@sjmc.org
Oklahoma University Medical Center, Oklahoma City, Oklahoma, 73104, United States; Recruiting
Joseph F. Montebello, MD 405-271-4022
Oregon
CCOP - Columbia River Oncology Program, Portland, Oregon, 97225, United States; Recruiting
Keith S. Lanier, MD 503-216-6260
Pennsylvania
Abington Memorial Hospital, Abington, Pennsylvania, 19001, United States; Recruiting
David Horvick, MD 215-481-2800 dhorvick@amh.org
Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, 19104-4283, United States; Recruiting
Mitchell Machtay, MD 215-662-2428 machtay@xrt.upenn.edu
Albert Einstein Cancer Center, Philadelphia, Pennsylvania, 19141-3098, United States; Recruiting
Sucha O. Asbell, MD 215-456-6280
Allegheny General Hospital, Pittsburgh, Pennsylvania, 15212-4772, United States; Recruiting
David S. Parda 412-359-8084 dparda@wpahs.org
CCOP - MainLine Health, Wynnewood, Pennsylvania, 19096, United States; Recruiting
Albert S. DeNittis, MD 610-645-2433 denittisa@mlhs.org
Dale and Frances Hughes Cancer Center at Pocono Medical Center, East Stroudsburg, Pennsylvania, 18301, United States; Recruiting
Michael J. Greenberg, MD 570-476-3488 mgreenb798@aol.com
Delaware County Regional Cancer Center at Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, 19026, United States; Recruiting
Rachelle M. Lanciano, MD 610-284-8240 RLancmd@aol.com
Fox Chase Cancer Center, Philadelphia, Pennsylvania, 19111, United States; Recruiting
Benjamin Movsas, MD 215-728-5304 b_movsas@fccc.edu
Geisinger Medical Center, Danville, Pennsylvania, 17822-0001, United States; Recruiting
A. Douglas Christie, MD 570-271-6304 achristie@geisiger.edu
Hillman Cancer Center at University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, 15232, United States; Recruiting
John M. Varlotto, MD 412-623-4000
John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital, Allentown, Pennsylvania, 18105-1556, United States; Recruiting
Victor R. Risch, MD 610-402-0700 victor.risch@lvh.com
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, 19107-5541, United States; Recruiting
Walter John Curran, MD 215-955-6700
Mercy Fitzgerald Hospital, Darby, Pennsylvania, 19023, United States; Recruiting
Leslie Tupchong, MD, PhD, FACR, MMM, CPE 610-237-4370 Ltupchong@mercyhealth.org
Mercy Hospital Cancer Center - Scranton, Scranton, Pennsylvania, 18501, United States; Recruiting
Harmar D. Brereton, MD 570-348-7200 brereton@epix.net
Mercy Hospital of Pittsburgh, Pittsburgh, Pennsylvania, 15219, United States; Recruiting
Michael J. Dougherty, MD 412-232-7475
Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey, Pennsylvania, 17033-0850, United States; Recruiting
David J. Salinger, MD 717-531-1523 dsalinger@psu.edu
Reading Hospital and Medical Center, Reading, Pennsylvania, 19612-6052, United States; Recruiting
Albert Yuen, MD 610-988-8067
St. Luke's Hospital Cancer Center, Bethlehem, Pennsylvania, 18015, United States; Recruiting
Nimisha Deb, MD 610-954-4300 DebN@slhn.org
Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, 15224, United States; Recruiting
Judith H. Figura, MD 412-578-1923 jhfigura2@wpahs.org
Wilkes-Barre General Hospital, Wilkes Barre, Pennsylvania, 18764-0001, United States; Recruiting
Robert A. Rostock, MD 570-552-1300 rrostock@wvhcs.org
York Cancer Center at Wellspan Health, York, Pennsylvania, 17403, United States; Recruiting
Ronald Malcom, MD 717-741-8100
Rhode Island
Roger Williams Medical Center, Providence, Rhode Island, 02908-4735, United States; Recruiting
Prakash B. Chougule, MD 401-456-2070
South Carolina
CCOP - Greenville, Greenville, South Carolina, 29615, United States; Recruiting
Michael D. Zurenko, MD 864-241-6251
CCOP - Upstate Carolina, Spartanburg, South Carolina, 29303, United States; Recruiting
James Dewitt Bearden, MD 864-560-7050
South Dakota
Rapid City Regional Hospital, Rapid City, South Dakota, 57709, United States; Recruiting
Daniel G. Petereit, MD 605-719-23
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
More Information
Clinical trial summary from the National Cancer Institute's PDQ® database
Study ID Numbers: CDR0000287213; RTOG-0244; NCT00068237
Record last reviewed: March 2005
Last Updated: April 5, 2005
Record first received: September 10, 2003
ClinicalTrials.gov Identifier: NCT00068237
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Record last reviewed: March 2005
Last Updated: April 5, 2005
Record first received: September 10, 2003
ClinicalTrials.gov Identifier: NCT00068237
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
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