Restless Legs Syndrome |
Restless Legs |
Restless legs syndrome (RLS, or Wittmaack-Ekbom's syndrome, which is not to be confused with Ekbom's syndrome) is a poorly understood and often misdiagnosed neurological disorder. Description RLS may be described as uncontrollable urges to move the limbs in order to stop uncomfortable, painful or odd sensations in the body, most commonly in the legs. Moving the affected body part eliminates the sensation, providing temporary relief. The sensations and need to move may return immediately ...
Wikipedia - [full article]
Restless Legs Syndrome Clinical Trials
- Swiss Restless Legs Syndrome Trial (SRLS)
ClinicalTrials.gov Identifier: NCT00144209 - Active, not recruiting
Restless Legs Syndrome
- Cross-Sectional Study: Prevalence of Restless Legs Syndrome in Patients With Unpleasant Sensations of the Legs
ClinicalTrials.gov Identifier: NCT00557258 - Active, not recruiting
Restless Legs Syndrome
- Relationship Between Sensory and Motor Systems in Restless Leg Syndrome
ClinicalTrials.gov Identifier: NCT00074672 - Active, not recruiting
Restless Legs Syndrome
- A Study To Look At The Starting Dose Of Ropinirole Immediate Release Tablets In Young Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00140712 - Recruiting
Restless Legs Syndrome
- An Extension Trial to Investigate Long-Term Treatment With Transdermal Rotigotine in Idiopathic Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00263068 - Active, not recruiting
Restless Legs Syndrome
- Non-Interventional Observational Study of Pramipexole in Restless Legs Syndrome: Impact on Quality of Life
ClinicalTrials.gov Identifier: NCT00539461 - Active, not recruiting
Restless Legs Syndrome
- Long-Term Study of XP13512 vs. Placebo in Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00311363 - Active, not recruiting
Restless Legs Syndrome
- Transdermal Lisuride: a Trial for the Treatment of Patients With Restless Legs Syndrome (RLS)
ClinicalTrials.gov Identifier: NCT00367822 - Active, not recruiting
Restless Legs Syndrome
- Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00355641 - Recruiting
Restless Legs Syndrome
- Restless Legs Syndrome Exercise Intervention
ClinicalTrials.gov Identifier: NCT00258492 - Active, not recruiting
Restless Legs Syndrome; Insomnia; Daytime Sleepiness
- XP13512 vs. Placebo in Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00365352 - Active, not recruiting
Restless Legs Syndrome
- A Randomized, Double-Blind, Placebo-Controlled Trial with 0.75mg Pramipexole (BI•Sifrol®) Orally Once Daily to Investigate the Efficacy and Safety for 6 Weeks in Patients with Primary Restless Legs Syndrome.
ClinicalTrials.gov Identifier: NCT00152997 - Completed
Restless Legs Syndrome
- Clinical Evaluation of Ropinirole CR-RLS ( SK&F106064)Tablets in Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00530790 - Not yet recruiting
Restless Legs Syndrome
- Long-Term Study Of Ropinirole In Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00329602 - Recruiting
Restless Legs Syndrome
- XP13512 Extension Study in Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00333359 - Recruiting
Restless Legs Syndrome
- SWITCH:Restless Legs Patients Switched to Ropinirole From Pramipexole
ClinicalTrials.gov Identifier: NCT00344994 - Recruiting
Restless Legs Syndrome
- A Double-Blind, Placebo-Controlled, Randomised Withdrawal Study of 3 Month Duration in Patients Suffering from Idiopathic Restless Legs Syndrome Who Responded to a Preceding, 6-Month Treatment with Open-Label Pramipexole Including Titration (0.125, 0.25,
ClinicalTrials.gov Identifier: NCT00152958 - Completed
Restless Legs Syndrome
- Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00051961 - Completed
Restless Legs Syndrome
- Botulinum Toxin to Treat Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00479154 - Recruiting
Restless Legs Syndrome
- ASP8825 - Study in Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00530530 - Recruiting
Restless Legs Syndrome
- The Effects Of Ropinirole On Mood Or Mild Depression In Patients With Moderate To Severe Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00357097 - Recruiting
Moderate to Severe Idiopathic Restless Legs Syndrome (RLS)
- A Sleep Lab Trial to Investigate the Efficacy and Safety of Transdermal Rotigotine in Subjects With Idiopathic Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00275236 - Completed
Restless Legs Syndrome
- A Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndrome (RLS)
ClinicalTrials.gov Identifier: NCT00247364 - Completed
Restless Legs Syndrome
- Efficacy and Safety of PPX (Pramipexole) in Moderate to Severe Idiopathic Restless Legs Syndrome (RLS) Patients
ClinicalTrials.gov Identifier: NCT00275457 - Completed
Restless Legs Syndrome
- Dose Finding Study of Pramipexole (Sifrol) in Patients With Idiopathic Restless Legs Syndrome (RLS).
ClinicalTrials.gov Identifier: NCT00239486 - Completed
Restless Legs Syndrome
- Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00199446 - Completed
Sleep Disorder; Restless Legs Syndrome
- A Clinical Research Study Evaluating Ropinirole Treatment For Restless Legs Syndrome (RLS)
ClinicalTrials.gov Identifier: NCT00225862 - Completed
Restless Legs Syndrome
- A Clinical Research Study Testing Ropinirole Treatment for Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00363857 - Completed
Restless Legs Syndrome
- Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00197080 - Completed
Restless Legs Syndrome
- Efficacy and Safety Study of Topiramate to Treat Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00200941 - Completed
Restless Legs Syndrome
- Restless Legs Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole And The Effect Of Food
ClinicalTrials.gov Identifier: NCT00419692 - Completed
Restless Legs Syndrome
- 12-Week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00373542 - Completed
Restless Legs
- XP13512 Versus Placebo in Patients With Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00298623 - Completed
Restless Legs Syndrome
- Sequential Compression Devices for Treatment of Restless Legs Syndrome
ClinicalTrials.gov Identifier: NCT00479531 - Completed
Restless Legs Syndrome
- A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Clinical Trial Comparing Fixed Doses of 0.25 Mg, 0.50 Mg and 0.75 Mg Pramipexole (Mirapex®) Administered Orally to Investigate the Safety and Efficacy in Patients with Idiopathic Restless
ClinicalTrials.gov Identifier: NCT00133198 - Completed
Restless Legs Syndrome
- Phase 3 Open-Label Extension Trial With Rotigotine in Idiopathic Restless Legs Syndrome Subjects
ClinicalTrials.gov Identifier: NCT00498108 - Completed
Idiopathic Restless Legs Syndrome
- Rotigotine Restless Legs Syndrome Dose Finding Trial
ClinicalTrials.gov Identifier: NCT00243217 - Completed
Idiopathic Restless Leg Syndrome
- A MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, FIVE-ARM PARALLEL-GROUP TRIAL TO INVESTIGATE THE EFFICACYAND SAFETY OF FOUR DIFFERENT TRANSDERMAL DOSES OF ROTIGOTINE IN SUBJECTS WITH IDIOPATHIC RESTLESS LEGS SYNDROME
ClinicalTrials.gov Identifier: NCT00135993 - Completed
Idiopathic Restless Leg syndrome
- Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)
ClinicalTrials.gov Identifier: NCT00256854 - Completed
Restless Legs Syndrome
- A Randomised, Comparing Fixed Doses of Pramipexole to Investigate the Efficacy and Safety in Patients With RLS.
ClinicalTrials.gov Identifier: NCT00390689 - Active, not recruiting
Restless Legs Syndrome
- A 6 Week Trial to Study the Efficacy and Safety of a Starting Dose 0.25 mg Pramipexole (Mirapex) in Patients With RLS
ClinicalTrials.gov Identifier: NCT00375284 - Active, not recruiting
Restless Legs Syndrome
- Long-Term Open-Label Trial in Idiopathic RLS Subjects
ClinicalTrials.gov Identifier: NCT00498186 - Active, not recruiting
Idiopathic Restless Legs Syndrome
- Long-Term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe RLS
ClinicalTrials.gov Identifier: NCT00472199 - Recruiting
Restless Legs Syndrome
- Comprehensive Police Fatigue Management Program
ClinicalTrials.gov Identifier: NCT00246051 - Not yet recruiting
Sleep Disorders; Sleep Apnea, Obstructive; Restless Legs Syndrome; Sleep Disorders, Circadian Rhythm; Sleep Initiation and Maintenance Disorders
- RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole
ClinicalTrials.gov Identifier: NCT00314860 - Active, not recruiting
Restless Legs Syndrome
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Proof-of-Concept Trial to Assess the Efficacy, Safety and Tolerability of Ascending Doses of Rotigotine Nasal Spray for the Acute Treatment of RLS Symptoms in Subjects With Idiopathic Restless
ClinicalTrials.gov Identifier: NCT00389831 - Completed
Idiopathic Restless Legs Syndrome
- Sleep Disorders Management, Health and Safety in Police
ClinicalTrials.gov Identifier: NCT00207285 - Recruiting
Sleep Disorders; Sleep Apnea, Obstructive; Restless Legs Syndrome; Sleep Disorders, Circadian Rhythm; Sleep Initiation and Maintenance Disorders
- Phase IV Trial With Pramipexole to Evaluate Safety and Efficacy in Patients With RLS Associated With Mood Disturbances
ClinicalTrials.gov Identifier: NCT00356096 - Completed
Restless Legs Syndrome; Depression
- A Phase IV Trial With Pramipexole to Investigate the Effects on RLS Symptoms and Sleep Disturbance in Patients With RLS
ClinicalTrials.gov Identifier: NCT00349531 - Completed
Restless Legs Syndrome
- Akathisia (Restless Legs Syndrome) in People with Schizophrenia and Mental Retardation
ClinicalTrials.gov Identifier: NCT00065286 - Completed
Akathisia
- Jugular Vein Sampling for Hormone Levels for the Diagnosis of Cushing Syndrome
ClinicalTrials.gov Identifier: NCT00001453 - Active, not recruiting
Cushing's Syndrome
- Study of Hypercortisolism in Cushing's Syndrome and Stress-Induced Pseudo-Cushing's Syndrome
ClinicalTrials.gov Identifier: NCT00004343 - Active, not recruiting
Cushing's Syndrome
- IGF-I/IGFBP-3 Therapy in Children and Adolescents With Growth Hormone Insenitivity Syndrome (GHIS) Such as Laron Syndrome
ClinicalTrials.gov Identifier: NCT00368173 - Active, not recruiting
Growth Hormone Insensitivity Syndrome (GHIS); Laron Syndrome
- Amifostine in Treating Patients With Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00003048 - Active, not recruiting
Previously Treated Myelodysplastic Syndrome; secondary myelodysplastic syndrome; de novo myelodysplastic syndrome
- Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders
ClinicalTrials.gov Identifier: NCT00004341 - Active, not recruiting
X-linked agammaglobulinemia; X-linked hyper IgM syndrome; Wiskott-Aldrich Syndrome; Leukocyte Adhesion Deficiency Syndrome
- Monoclonal Antibody Therapy in Treating Patients With Primary Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00003984 - Active, not recruiting
Previously Treated Myelodysplastic Syndrome; secondary myelodysplastic syndrome; de novo myelodysplastic syndrome; ...
- Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters
ClinicalTrials.gov Identifier: NCT00006445 - Active, not recruiting
Down Syndrome; Chromosome Abnormalities
- Anti-CD20 Antibody Therapy for Sjogren's Syndrome
ClinicalTrials.gov Identifier: NCT00101829 - Active, not recruiting
Sjogren's Syndrome
- Vaccine Therapy in Treating Patients With Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00003959 - Active, not recruiting
Refractory Anemia; Previously Treated Myelodysplastic Syndrome; secondary myelodysplastic syndrome; refractory anemia with ringed sideroblasts; ...
- Modafinil to Treat Fatigue in Post-Polio Syndrome
ClinicalTrials.gov Identifier: NCT00067496 - Active, not recruiting
Postpoliomyelitis Syndrome
- The effect of androgen and growth hormone on height and learning in girls with Turner syndrome
ClinicalTrials.gov Identifier: NCT00029159 - Active, not recruiting
Turner Syndrome
- MPS I Registry
ClinicalTrials.gov Identifier: NCT00144794 - Recruiting
Mucopolysaccharidosis I; Hurler''s Syndrome; Hurler-Scheie Syndrome; Scheie Syndrome
- Amifostine With or Without Epoetin alfa in Treating Patients With Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00003681 - Active, not recruiting
Refractory Anemia; Previously Treated Myelodysplastic Syndrome; Anemia; secondary myelodysplastic syndrome; ...
- Antidepressant Treatment for Premenstrual Syndrome and Premenstrual Dysphoric Disorder
ClinicalTrials.gov Identifier: NCT00048854 - Active, not recruiting
Premenstrual Syndrome
- Detection of Residual Disease in Children Receiving Therapy for Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00003790 - Active, not recruiting
Previously Treated Myelodysplastic Syndrome; untreated childhood acute myeloid leukemia; secondary myelodysplastic syndrome; ...
- Carperitide in Acute Respiratory Distress Syndrome (ARDS)
ClinicalTrials.gov Identifier: NCT00030121 - Active, not recruiting
Respiratory Distress Syndrome
- Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer
ClinicalTrials.gov Identifier: NCT00033137 - Recruiting
Syndrome
- Manifestations of Heritable Disorders of Connective Tissue
ClinicalTrials.gov Identifier: NCT00270686 - Recruiting
Ehlers-Danlos Syndrome; Marfan Syndrome; Stickler Syndrome
- Pilot Study of Allogeneic Bone Marrow Transplantation Plus Cyclosporine and Mycophenolate Mofetil to Induce Mixed Hematopoietic Chimerism in Patients With Primary T-Cell Immunodeficiency Disorders
ClinicalTrials.gov Identifier: NCT00008450 - Recruiting
Purine-Pyrimidine Metabolism, Inborn Errors; Wiskott-Aldrich Syndrome; Bare Lymphocyte Syndrome; Lymphopenia; Job's Syndrome; DiGeorge Syndrome; ...
- Pioglitazone Treatment in Polycystic Ovary Syndrome
ClinicalTrials.gov Identifier: NCT00145340 - Active, not recruiting
Polycystic Ovary Syndrome
- Down Syndrome and Continuous Positive Pressure Therapy
ClinicalTrials.gov Identifier: NCT00394290 - Recruiting
Down Syndrome; Obstructive Sleep Apnea Syndrome
- Study of Tics in Patients with Tourette's Syndrome and Chronic Motor Tic Disorder
ClinicalTrials.gov Identifier: NCT00033995 - Active, not recruiting
Tourette Syndrome; Tic Disorders
- Combination Treatment With Bosentan and Sildenafil to Patients With Eisenmengers Syndrome
ClinicalTrials.gov Identifier: NCT00303004 - Active, not recruiting
Eisenmenger Syndrome
- Effect of MAXOMAT ® on the Growth of Small Children to NOONAN's Syndrome
ClinicalTrials.gov Identifier: NCT00452725 - Active, not recruiting
Noonan Syndrome
- Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue
ClinicalTrials.gov Identifier: NCT00543166 - Active, not recruiting
Sjogren's Syndrome
- Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
ClinicalTrials.gov Identifier: NCT00006054 - Active, not recruiting
Immunologic Deficiency Syndromes; Chediak-Higashi Syndrome; Common Variable Immunodeficiency; Graft Versus Host Disease; ...
- Vitamin E in Aging Persons With Down Syndrome
ClinicalTrials.gov Identifier: NCT00056329 - Active, not recruiting
Down Syndrome; Alzheimer Disease
- Open-Label Extension Of Intravenous Mepolizumab In Patients With Hypereosinophilic Syndrome
ClinicalTrials.gov Identifier: NCT00097370 - Active, not recruiting
Hypereosinophilic Syndrome; Hypereosinophilia
- Study of the Safety and Efficacy of CC-5013 Treatment For Patients with Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00044382 - Active, not recruiting
Myelodysplastic Syndrome
- Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants
ClinicalTrials.gov Identifier: NCT00433485 - Active, not recruiting
Neoplastic Syndrome; Non-Melanomatous Skin Cancer
- Evaluation of a Venous-Return Assist Device (Venowave) to Treat Post-Thrombotic Syndrome: A Randomized Controlled Trial
ClinicalTrials.gov Identifier: NCT00182208 - Active, not recruiting
Postphlebitic Syndrome
- Study of High-dose Pulse Administration DN-101 (Calcitriol) in Patients with Myelodysplastic Syndrome (MDS)
ClinicalTrials.gov Identifier: NCT00057031 - Active, not recruiting
Myelodysplastic Syndrome
- Antiphospholipid Syndrome Collaborative Registry (APSCORE)
ClinicalTrials.gov Identifier: NCT00076713 - Active, not recruiting
Antiphospholipid Syndrome
- Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome
ClinicalTrials.gov Identifier: NCT00068913 - Active, not recruiting
MELAS Syndrome
- Management of Compartment Syndrome with Ultrafiltration
ClinicalTrials.gov Identifier: NCT00022815 - Active, not recruiting
Compartment Syndrome
- Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases
ClinicalTrials.gov Identifier: NCT00003662 - Active, not recruiting
Graft Versus Host Disease; Refractory Anemia; Previously Treated Myelodysplastic Syndrome; secondary myelodysplastic syndrome; ...
- Randomized, Placebo-Controlled Study of Leptin for the Treatment of HIV Lipodystrophy and Metabolic Syndrome
ClinicalTrials.gov Identifier: NCT00140244 - Active, not recruiting
HAART-induced lipodystrophy and metabolic syndrome
- Carpal Tunnel Syndrome: Diagnosis and Treatment Trial
ClinicalTrials.gov Identifier: NCT00032227 - Active, not recruiting
Carpal Tunnel Syndrome
- A Phase 4 Study Investigating the Relationship Between the Development of Laronidase Antibody and Urinary GAG Levels in Aldurazyme® (Laronidase) Treated Patients.
ClinicalTrials.gov Identifier: NCT00144768 - Recruiting
Mucopolysaccharidosis I; Hurler''s Syndrome; Hurler-Scheie Syndrome; Scheie Syndrome
- Gemtuzumab Ozogamicin, Fludarabine, and Total-body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00008151 - Active, not recruiting
Previously Treated Myelodysplastic Syndrome; secondary myelodysplastic syndrome; recurrent adult acute myeloid leukemia; ...
- Retraining Walking after Spinal Cord Injury
ClinicalTrials.gov Identifier: NCT00059553 - Active, not recruiting
Spinal Cord Injuries; Quadriplegia; Paraplegia; Central Cord Syndrome; Brown-Sequard Syndrome
- Study of GABA-A receptors in the Generation of Tics in Patients with Tourette's Syndrome
ClinicalTrials.gov Identifier: NCT00034398 - Recruiting
Tourette Syndrome
- Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders
ClinicalTrials.gov Identifier: NCT00006056 - Active, not recruiting
Chediak-Higashi Syndrome; Graft Versus Host Disease; X-Linked Lymphoproliferative Syndrome; Familial Erythrophagocytic Lymphohistiocytosis; ...
- Sleep Disordered Breathing in Gulf War Syndrome Veterans and the Effect of Continuous Positive Airway Pressure (CPAP) Treatment
ClinicalTrials.gov Identifier: NCT00252629 - Recruiting
Gulf War Syndrome; Chronic Fatigue Syndrome; Functional Somatic Syndrome; Upper Airway Resistance Syndrome; Sleep Apnea
- Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection (Job Syndrome)
ClinicalTrials.gov Identifier: NCT00006150 - Recruiting
Job's Syndrome
- Topotecan in Treating Patients With Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00003675 - Active, not recruiting
Refractory Anemia; secondary myelodysplastic syndrome; refractory anemia with ringed sideroblasts; de novo myelodysplastic syndrome; ...
- An Implantable Microstimulator for the Chronic Treatment of Refractory Urinary Urgency-Frequency Syndrome
ClinicalTrials.gov Identifier: NCT00131573 - Active, not recruiting
Urinary Urgency-Frequency Syndrome
- Impact of Exercise Training Intensity on Abdominal Visceral Fat and Risk Factors Associated With the Metabolic Syndrome
ClinicalTrials.gov Identifier: NCT00350064 - Active, not recruiting
Metabolic Syndrome
- CHUSPAN SCS BP Treatment of Churg–Strauss Syndrome Without Poor-Prognosis Factors
ClinicalTrials.gov Identifier: NCT00399399 - Active, not recruiting
Churg-Strauss Syndrome
- Risk of Guillain-Barré Syndrome Following Meningococcal Conjugate (MCV4) Vaccination Menactra and GBS
ClinicalTrials.gov Identifier: NCT00575653 - Active, not recruiting
Guillain-Barre Syndrome

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