Scleroderma Clinical Trials

• Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls
  ClinicalTrials.gov Identifier: NCT00213525 - Recruiting
  Scleroderma
  
• Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung Involvement
  ClinicalTrials.gov Identifier: NCT00333437 - Recruiting
  Scleroderma, Systemic
  
• Efficacy and Safety of Imatinib in Scleroderma
  ClinicalTrials.gov Identifier: NCT00479934 - Not yet recruiting
  Scleroderma, Localized; Scleroderma, Systemic
  
• Psychological Treatments for Scleroderma
  ClinicalTrials.gov Identifier: NCT00007267 - Active, not recruiting
  Pain; Depression; Scleroderma; Systemic Sclerosis
  
• Oral Type I Collagen for Relieving Scleroderma
  ClinicalTrials.gov Identifier: NCT00005675 - Active, not recruiting
  Scleroderma; Connective Tissue Diseases
  
• Premature Coronary Atherosclerosis in Scleroderma, a Case Control Study
  ClinicalTrials.gov Identifier: NCT00372398 - Recruiting
  Scleroderma
  
• Placebo Controlled Trial of Bosentan in Scleroderma Patients
  ClinicalTrials.gov Identifier: NCT00377455 - Recruiting
  Systemic Scleroderma; Pulmonary Hypertension
  
• UVA1 Light for Scleroderma and Similar Conditions
  ClinicalTrials.gov Identifier: NCT00476697 - Recruiting
  Keloid; Scleroderma; Scars; Granuloma Annulare; Acne Keloidalis Nuchae
  
• High Dose Cyclophosphamide for Treatment of Scleroderma
  ClinicalTrials.gov Identifier: NCT00501995 - Recruiting
  Scleroderma
  
• Scleroderma: Cyclophosphamide or Transplantation (SCOT)
  ClinicalTrials.gov Identifier: NCT00114530 - Recruiting
  Scleroderma, Systemic; Sclerosis
  
• A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma)
  ClinicalTrials.gov Identifier: NCT00442611 - Recruiting
  Scleroderma, Diffuse; Scleroderma, Systemic; Systemic Sclerosis
  
• Cyclophosphamide and rATG With Hematopoietic Stem Cell Support in Systemic Scleroderma
  ClinicalTrials.gov Identifier: NCT00278525 - Recruiting
  Systemic Scleroderma
  
• UVA1 Light for Treatment of Scleroderma and Similar Conditions
  ClinicalTrials.gov Identifier: NCT00476801 - Recruiting
  Scleroderma; Keloids; Other Fibrosing Conditions
  
• Multi-Center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma Patients
  ClinicalTrials.gov Identifier: NCT00377949 - Recruiting
  Systemic Sclerosis; Scleroderma; Pulmonary Hypertension
  
• Scleroderma Registry
  ClinicalTrials.gov Identifier: NCT00074568 - Recruiting
  Systemic Sclerosis; Scleroderma
  
• Imiquimod in Children with Plaque Morphea
  ClinicalTrials.gov Identifier: NCT00147771 - Recruiting
  Morphea (localized scleroderma)
  
• Scleroderma Lung Study
  ClinicalTrials.gov Identifier: NCT00004563 - Completed
  Lung Diseases; Pulmonary Fibrosis; Systemic Scleroderma; Scleroderma, Systemic
  
• Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Scleroderma Patients
  ClinicalTrials.gov Identifier: NCT00077584 - Completed
  Systemic Sclerosis; Scleroderma
  
• The Effectiveness of UVB Light Therapy in the Treatment of Skin Conditions with Altered Dermal Matrix
  ClinicalTrials.gov Identifier: NCT00129428 - Recruiting
  Keloid; Scleroderma; Acne Keloidalis Nuchae; Scars; Granuloma Annulare
  
• Study of Families with Twins or Siblings Discordant for Rheumatic Disorders
  ClinicalTrials.gov Identifier: NCT00055055 - Recruiting
  Rheumatic Diseases; Rheumatoid Arthritis; Systemic Lupus Erythematosus; Scleroderma; Dermatomyositis; Myositis
  
• Sleep Disturbances and Pulmonary Artery/Aorta Diameter in Scleroderma Patient
  ClinicalTrials.gov Identifier: NCT00566137 - Completed
  Scleroderma; Pulmonary Hypertension
  
• Allogeneic Hematopoietic Stem Cell Transplantation (NST) for Patients With Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00282425 - Recruiting
  Scleroderma
  
• Effects of a Personalized Standardized Rehabilitation Program in Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00318188 - Recruiting
  Systemic Scleroderma
  
• Efficacy and safety of oral bosentan in pulmonary fibrosis associated with scleroderma
  ClinicalTrials.gov Identifier: NCT00070590 - Completed
  Pulmonary Fibrosis; Scleroderma, Systemic
  
• Efficacy and Safety Study of GB-0998 for Treatment of Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00348296 - Recruiting
  Scleroderma, Systemic
  
• Comparison of Esophageal and Anorectal Manometry Catheters
  ClinicalTrials.gov Identifier: NCT00204763 - Recruiting
  Achalasia; Nutcracker Esophagus; Scleroderma; Esophageal Spasm; Fecal Incontinence
  
• Platelet Gel in Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00463125 - Recruiting
  Scleroderma, Systemic
  
• High Dose Intravenous N-Acetylcysteine Versus Iloprost for Early, Rapidly Progressive Diffuse Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00428883 - Recruiting
  Scleroderma, Diffuse
  
• Imatinib in Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00506831 - Recruiting
  Scleroderma, Systemic
  
• Study of Silicone-Associated Connective Tissue Diseases
  ClinicalTrials.gov Identifier: NCT00001330 - Completed
  Autoimmune Diseases; Connective Tissue Diseases; Scleroderma, Circumscribed; Scleroderma, Systemic
  
• Optical Biopsy of Human Skin in Conjunction With Laser Treatment
  ClinicalTrials.gov Identifier: NCT00540566 - Enrolling by invitation
  Malignant Melanoma,; Merkel Cell Carcinoma,; Basal Cell Carcinoma,; Squamous Cell Carcinoma; Atypical Nevi,; Congenital Nevi; Seborrheic Keratosis,; Paget's Disease; Dermatofibroma,; Kaposi's Sarcoma; Hypervascular Congenital Malformations; Port Wine Stain; Hemangioma; Tattoos; Scleroderma; Burns; Normal Skin
  
• Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement
  ClinicalTrials.gov Identifier: NCT00573326 - Not yet recruiting
  Systemic Sclerosis
  
• Treatment of Early Systemic Sclerosis by Bosentan
  ClinicalTrials.gov Identifier: NCT00226889 - Recruiting
  Systemic Sclerosis (Scleroderma)
  
• Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients
  ClinicalTrials.gov Identifier: NCT00040651 - Terminated
  Scleroderma; Systemic Sclerosis
  
• A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon
  ClinicalTrials.gov Identifier: NCT00577304 - Recruiting
  Raynaud's Disease; Raynaud's Disease Secondary to Scleroderma; Raynaud's Disease Secondary to Other Autoimmune Disease
  
• CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study
  ClinicalTrials.gov Identifier: NCT00522002 - Recruiting
  Connective Tissue Diseases; Blood Coagulation Disorders; Leg Ulcers; Rheumatoid Arthritis; Systemic Lupus Erythematosus; Systemic Scleroderma; Mixed Connective Tissue Disease
  
• Duke Autoimmunity in Pregnancy Registry
  ClinicalTrials.gov Identifier: NCT00513591 - Not yet recruiting
  Pregnancy; Systemic Lupus Erythematosus; Cutaneous Lupus; Rheumatoid Arthritis; Sjogren's Syndrome; Scleroderma
  
• Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients with Early Stage Diffuse Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00043706 - Completed
  Systemic Sclerosis; Scleroderma
  
• Six month clinical research study for patients with moderate or severe dry eye syndrome
  ClinicalTrials.gov Identifier: NCT00025818 - Completed
  Keratoconjunctivitis Sicca; Sjogren's Syndrome; Lupus Erythematosus, Systemic; Arthritis, Rheumatoid; Scleroderma, Systemic
  
• Idiopathic Pulmonary Fibrosis--Pathogenesis and Staging - SCOR in Occupational and Immunological Lung Diseases
  ClinicalTrials.gov Identifier: NCT00005317 - Completed
  Lung Diseases; Pulmonary Fibrosis; Lung Diseases, Interstitial; Scleroderma, Systemic
  
• Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-Year Manometric Follow-Up
  ClinicalTrials.gov Identifier: NCT00213460 - Completed
  Systemic Sclerosis
  
• Phase III Study of a Topical Gel Formulation for Treatment and Prevention of Raynaud's Phenomenon
  ClinicalTrials.gov Identifier: NCT00419419 - Completed
  Raynaud's Disease; Scleroderma; Autoimmune Diseases
  
• Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00318175 - Completed
  Systemic Scleroderma; Skin Fibrosis; Hand Functionality
  
• Open-Label Study With Bosentan in Interstitial Lung Disease
  ClinicalTrials.gov Identifier: NCT00319033 - Completed
  Interstitial Lung Disease; Scleroderma
  
• Lab Study of MQX-503 in Treatment of Raynaud's
  ClinicalTrials.gov Identifier: NCT00253331 - Completed
  Raynaud Disease; Raynaud Disease Secondary to Scleroderma; Raynaud Secondary to Other Autoimmune Disease
  
• Dose Response Study of a Topical Gel for the Treatment of Raynaud's Phenomenon
  ClinicalTrials.gov Identifier: NCT00378521 - Completed
  Raynaud's Disease; Raynaud's Disease Secondary to Scleroderma; Raynaud's Disease Secondary to Autoimmune Disease
  
• Thalidomide for Decreasing Collagen Biosynthesis in People With Progressive Systemic Sclerosis
  ClinicalTrials.gov Identifier: NCT00418132 - Terminated
  Scleroderma, Systemic