Sickle Cell Anemia |
Hb S disease; Hemoglobin S Disease; Herrick's anemia; SCD |
Sickle-cell disease is a general term for a group of genetic disorders caused by sickle hemoglobin (Hgb S or Hb S). In many forms of the disease, the red blood cells change shape upon deoxygenation because of polymerization of the abnormal sickle hemoglobin. This process damages the red blood cell membrane, and can cause the cells to become stuck in blood vessels. This deprives the downstream tissues of oxygen and causes ischemia and infarction. The disease is chronic and lifelong. Individu ...
Wikipedia - [full article]
Resources
- Anemia (HealthWorld)
- Ask NOAH About Pregnancy: Sickle Cell Disease (March of Dimes Birth Defects Foundation)
- Blood and Marrow Stem Cell Transplantation (Leukemia & Lymphoma Society)
- Blood Transfusions (Nemours Foundation)
- Bone Marrow and Cord Blood Stem Cell Transplant (Georgia Comprehensive Sickle Cell Center at Grady Health System)
- Cartilha de Anemia Falciforme (Georgia Comprehensive Sickle Cell Center at Grady Health System)
- Child with Sickle Cell Disease-A Teaching Manual: Genetics (Georgia Comprehensive Sickle Cell Center at Grady Health System)
- ClinicalTrials.gov: Anemia, Sickle Cell (National Institutes of Health)
- Complete Blood Count (American Association for Clinical Chemistry)
- Do You Know about Sickle Cell Anemia? (Nemours Foundation)
- Exploring Important Medicinal Uses for Watermelon Rinds (Dept. of Agriculture)
- Exposure to Tobacco Smoke Harms Children with Sickle Cell Disease (Nemours Foundation)
- Frequently Asked Questions (Sickle Cell Disease Association of America)
- Genes and Disease (National Center for Biotechnology Information, NLM, NIH, HHS)
- Genes and Disease: Sickle Cell Anemia (National Center for Biotechnology Information)
- Genetic Counseling (Nemours Foundation)
- Genetic Disease Profile: Sickle Cell Anemia (Dept. of Energy, Human Genome Project)
- Genetics Home Reference: Sickle cell anemia (Genetics Home Reference)
- Glossary (Sickle Cell Disease Association of America)
- High Blood Pressure in the Lungs a Major Risk for Death in Adults with Sickle Cell Disease (National Institutes of Health)
- How Do People Get Sickle Cell Disease? (Brigham and Women's Hospital, Harvard Medical School, Massachusetts General Hospital)
- Hydroxyurea Therapy Improves Survival in Most Severely Affected Sickle Cell Patients (National Institutes of Health)
- Learning about Sickle Cell Disease (National Human Genome Research Institute)
- Management of Sickle Cell Disease, The (National Heart, Lung, and Blood Institute Information Center, NHLBI, NIH, HHS)
- National Heart, Lung, and Blood Institute
- Newborn Screening for Sickle Cell Disease and Other Hemoglobinopathies (Office of Medical Applications of Research)
- Newborn Screening Tests (March of Dimes Birth Defects Foundation)
- Pain Assessment and Pain Management in Sickle Cell Disease (Sickle Cell Information Center, The)
- Save Babies Through Screening Foundation (Save Babies Through Screening)
- Scientists Use Gene Therapy to Correct Sickle Cell Disease in Mice (National Heart, Lung, and Blood Institute)
- Sickle Cell Anemia (Cleveland Clinic)
- Sickle Cell Anemia (Cleveland Clinic)
- Sickle Cell Anemia (HealthWorld)
- Sickle Cell Anemia (HealthWorld)
- Sickle Cell Anemia (National Women's Health Information Center)
- Sickle Cell Anemia (Medline Plus)
- Sickle Cell Anemia (National Heart, Lung, and Blood Institute Information Center, NHLBI, NIH, HHS)
- Sickle Cell Anemia (Nemours Foundation)
- Sickle Cell Anemia (MayoClinic)
- Sickle Cell Anemia (Nemours Foundation)
- Sickle Cell Anemia (National Institutes of Health)
- Sickle Cell Anemia (Lab Tests Online)
- Sickle Cell Clinics, Contacts, and Resources (Georgia Comprehensive Sickle Cell Center at Grady Health System)
- Sickle Cell Disease (Cleveland Clinic)
- Sickle Cell Disease Association of America
- Sickle Cell Disease: Americans with Disabilities Act (Georgia Comprehensive Sickle Cell Center at Grady Health System)
- Sickle Cell Disease: Practical Tips for Preventing a Sickle Cell Crisis (American Academy of Family Physicians)
- Sickle Cell Information Center (Georgia Comprehensive Sickle Cell Center at Grady Health System)
- Sickle Cell Research for Treatment and Cure (National Heart, Lung, and Blood Institute) - Links to PDF File - Large file
- Sickle Cell Test (American Association for Clinical Chemistry)
- The Management of Sickle Cell Disease (National Heart, Lung and Blood Institute)
- Truth about Transfusions (Nemours Foundation)
- What Is Sickle Cell Disease? (Dolan DNA Learning Center)
- What Is Sickle Cell Disease? (Sickle Cell Disease Association of America, Inc.)
- Who Is Affected? (Sickle Cell Disease Association of America)

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