Sickle Cell Anemia Clinical Trials

• Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00095472 - Active, not recruiting
  Sickle Cell Anemia
  
• Hydroxyurea for the Treatment of Patients with Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00001197 - Active, not recruiting
  Sickle Cell Anemia
  
• Ketorolac Versus Ibuprofen for the Painful Crisis of Sickle Cell Disease - Southwestern Comprehensive Sickle Cell Center
  ClinicalTrials.gov Identifier: NCT00115336 - Recruiting
  Blood Disease; Anemia, Sickle Cell
  
• Inhaled Nitric Oxide and Transfusion Therapy for Patients with Sickle Cell Anemia and Secondary Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00023296 - Active, not recruiting
  Sickle Cell Anemia; Pulmonary Hypertension
  
• Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00012545 - Recruiting
  Healthy; Sickle Cell Anemia
  
• Trial of Oral Glutamine in Patients with Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00131508 - Recruiting
  Anemia, Sickle Cell
  
• Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH)
  ClinicalTrials.gov Identifier: NCT00000586 - Active, not recruiting
  Anemia, Sickle Cell; Hematologic Diseases; Hemoglobinopathies
  
• Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises
  ClinicalTrials.gov Identifier: NCT00094887 - Recruiting
  Anemia, Sickle Cell
  
• L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia
  ClinicalTrials.gov Identifier: NCT00125788 - Active, not recruiting
  Sickle Cell Anemia (homozygous); Sickle ß0-Thalassemia
  
• Bone Marrow Transplantation in Treating Children With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00004485 - Active, not recruiting
  Sickle Cell Anemia
  
• Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients
  ClinicalTrials.gov Identifier: NCT00029731 - Recruiting
  Anemia, Sickle Cell; Pneumonia
  
• Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia
  ClinicalTrials.gov Identifier: NCT00512564 - Not yet recruiting
  Sickle Cell Anemia; Sickle Cell Thalassemia
  
• Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00056433 - Active, not recruiting
  Sickle Cell Anemia
  
• Pediatric Hydroxyurea in Sickle Cell Anemia (BABY HUG)
  ClinicalTrials.gov Identifier: NCT00006400 - Recruiting
  Blood Disease; Anemia, Sickle Cell
  
• Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00004408 - Active, not recruiting
  Sickle Cell Anemia
  
• Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00006130 - Active, not recruiting
  Bone Avascular Necrosis; Sickle Cell Anemia
  
• Pediatrics:Chlamydia, Sickle Cell Anemia and Stroke Risk - Ancillary to STOP II
  ClinicalTrials.gov Identifier: NCT00037388 - Active, not recruiting
  Blood Disease; Anemia, Sickle Cell; Chlamydia Infections; Cerebrovascular Accident
  
• Study of Oral ICL670 (Deferasirox) Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients
  ClinicalTrials.gov Identifier: NCT00110617 - Active, not recruiting
  Sickle Cell Disease; Iron Overload; Hemolytic Anemia
  
• Pain in Sickle Cell Epidemiologic Study
  ClinicalTrials.gov Identifier: NCT00035763 - Active, not recruiting
  Blood Disease; Anemia, Sickle Cell
  
• A study of the efficacy and safety of ICA-17043 (with or without hydroxyurea) in patients with sickle cell anemia.
  ClinicalTrials.gov Identifier: NCT00040677 - Completed
  Sickle Cell Disease; Sickle Cell Anemia
  
• Establishing a Repository of Blood and DNA Samples From People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Genotype-Phenotype Database and Sample Repository)
  ClinicalTrials.gov Identifier: NCT00528203 - Recruiting
  Anemia, Sickle Cell
  
• Silent Cerebral Infarct Multi-Center Clinical Trial
  ClinicalTrials.gov Identifier: NCT00072761 - Recruiting
  Sickle Cell Anemia; Stroke
  
• Induction of Stable Chimerism for Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00029393 - Active, not recruiting
  Blood Disease; Hematopoietic Stem Cell Transplantation; Anemia, Sickle Cell
  
• Establishing a Database of People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Data Project [C-Data])
  ClinicalTrials.gov Identifier: NCT00529061 - Recruiting
  Anemia, Sickle Cell
  
• Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00143572 - Active, not recruiting
  Anemia, Sickle Cell
  
• Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00399074 - Recruiting
  Sickle Cell Anemia; Malaria
  
• Nitric Oxide to Improve Blood Flow in Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00009581 - Completed
  Sickle Cell Anemia
  
• L-glutamine Therapy for Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00029887 - Recruiting
  Anemia, Sickle Cell; Thalassemia
  
• Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea
  ClinicalTrials.gov Identifier: NCT00480974 - Not yet recruiting
  Sickle Cell Anemia; Sickle Cell Thalassemia
  
• Stem Cell Transplantation after Reduced-Dose Chemotherapy for Patients with Sickle Cell Disease or Thalassemia
  ClinicalTrials.gov Identifier: NCT00034528 - Active, not recruiting
  Hemoglobinopathies; Anemia, Sickle Cell; Hemoglobin SC Disease; Thalassemia; Thalassemia Major
  
• Effectiveness of Arginine as a Treatment for Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00513617 - Recruiting
  Anemia, Sickle Cell
  
• Tadalafil for Treatment of Priapism in Men With Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00538564 - Recruiting
  Sickle Cell Anemia; Priapism; Pulmonary Hypertension
  
• Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes
  ClinicalTrials.gov Identifier: NCT00004404 - Recruiting
  Sickle Cell Anemia
  
• Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00004492 - Recruiting
  Sickle Cell Anemia
  
• Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00528801 - Recruiting
  Anemia, Sickle Cell
  
• Dexamethasone to Treat Acute Chest Syndrome in People With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00530270 - Recruiting
  Anemia, Sickle Cell
  
• Effects of Nitric Oxide and Nitroglycerin in Patients with Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00001716 - Completed
  Chest Pain; Sickle Cell Anemia
  
• MAST – Magnesium for Sickle Cell Acute Crisis in Children
  ClinicalTrials.gov Identifier: NCT00313963 - Recruiting
  Anemia, Sickle Cell
  
• Phase II Randomized Trial of Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers
  ClinicalTrials.gov Identifier: NCT00004412 - Recruiting
  Skin Ulcers; Sickle Cell Anemia
  
• Dipyridamole/Magnesium To Improve Sickle Cell Hydration
  ClinicalTrials.gov Identifier: NCT00276146 - Recruiting
  Anemia, Sickle Cell
  
• Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients with Iron Overload due to Blood Transfusions
  ClinicalTrials.gov Identifier: NCT00067080 - Completed
  Anemia, Sickle Cell
  
• Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia
  ClinicalTrials.gov Identifier: NCT00512226 - Not yet recruiting
  Sickle Cell Anemia; Sickle Cell Thalassemia; Iron Overload; MRI
  
• Role of Placenta Growth Factor in Sickle Acute Chest Syndrome
  ClinicalTrials.gov Identifier: NCT00448370 - Recruiting
  Anemia, Sickle Cell
  
• Secondary Pulmonary Hypertension in Adults with Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00011648 - Recruiting
  Pulmonary Hypertension; Sickle Cell Anemia
  
• Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00270478 - Recruiting
  Sickle Cell Disease; Chronic Kidney Disease; Pulmonary Hypertension
  
• Sibling Donor Cord Blood Banking and Transplantation
  ClinicalTrials.gov Identifier: NCT00029380 - Recruiting
  Blood Disease; Anemia, Sickle Cell; Anemia (Cooley's); Leukemia; Bone Marrow Transplantation; Hematopoietic Stem Cell Transplantation
  
• Sickle Cell Anemia in an Arab Bedouin Village in the Jezreel Valley
  ClinicalTrials.gov Identifier: NCT00481039 - Not yet recruiting
  Sickle Cell Disease
  
• The Link Between Anemia and Deficits in Memory and Attention in Individuals With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00451919 - Recruiting
  Sickle Cell Disease
  
• Stroke with Transfusions Changing to Hydroxyurea (SWITCH)
  ClinicalTrials.gov Identifier: NCT00122980 - Recruiting
  Hemochromatosis; Cerebrovascular Accident; Anemia, Sickle Cell; Blood Disease
  
• Pilot Study of Fructose for Sickle Cell Crisis
  ClinicalTrials.gov Identifier: NCT00004797 - Completed
  Sickle Cell Anemia
  
• Prevention of Cerebral Infarction in Sickle Cell Anemia - Comprehensive Sickle Cell Center
  ClinicalTrials.gov Identifier: NCT00005327 - Completed
  Anemia, Sickle Cell; Blood Disease; Cerebrovascular Disorders; Cerebrovascular Accident
  
• Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG
  ClinicalTrials.gov Identifier: NCT00059293 - Active, not recruiting
  Blood Disease; Anemia, Sickle Cell; Cerebrovascular Disorders; Cerebral Embolism and Thrombosis
  
• Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG)
  ClinicalTrials.gov Identifier: NCT00000602 - Completed
  Anemia, Sickle Cell; Hematologic Diseases; Hemoglobinopathies
  
• A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study
  ClinicalTrials.gov Identifier: NCT00360087 - Active, not recruiting
  Pulmonary Hypertension; Sickle Cell Anemia
  
• Stroke Prevention in Sickle Cell Anemia (STOP 2)
  ClinicalTrials.gov Identifier: NCT00006182 - Completed
  Blood Disease; Cerebrovascular Accident; Anemia, Sickle Cell
  
• Investigation of Selected Patient Groups From The Cooperative Study of Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00005300 - Completed
  Anemia, Sickle Cell; Blood Disease
  
• Priapism in Men With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00300235 - Recruiting
  Priapism; Anemia, Sickle Cell
  
• Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00072826 - Active, not recruiting
  Sickle Cell Disease
  
• Hydroxyurea in Young Children With Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00519701 - Completed
  Sickle Cell Anemia
  
• Stroke Prevention in Sickle Cell Anemia (STOP 1)
  ClinicalTrials.gov Identifier: NCT00000592 - Completed
  Anemia, Sickle Cell; Cerebral Embolism and Thrombosis; Cerebrovascular Disorders; Hematologic Diseases; Hemoglobinopathies
  
• Haploidentical Stem Cell (HSC)Transplantation for Sickle Cell Disease Patients with a Stroke/Abnormal TCD
  ClinicalTrials.gov Identifier: NCT00152113 - Active, not recruiting
  Sickle Cell Disease
  
• Pulmonary Hypertension, Hypoxia and Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00495638 - Recruiting
  Chuvash Polycythemia; Cerebrovascular Disease; Pulmonary Hypertension; Sickle Cell Anemia
  
• High Throughput Screening of Compound Libraries to Discover a Drug for the Treatment of Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00542230 - Recruiting
  Sickle Cell Trait; Sickle Cell Disease
  
• A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients with Sickling Disorders
  ClinicalTrials.gov Identifier: NCT00005783 - Completed
  hemoglobin SC disease; sickle cell anemia
  
• Quality of Life of Children With Sickle Cell Disease Who Are Getting Chronic Transfusions With a Lifeport
  ClinicalTrials.gov Identifier: NCT00246077 - Completed
  Anemia, Sickle Cell
  
• Phase I/II Study of Nonmyeloablative Allogeneic Bone Marrow Transplantation in Patients With High Risk Hemoglobinopathy
  ClinicalTrials.gov Identifier: NCT00005897 - Recruiting
  Graft Versus Host Disease; Sickle Cell Anemia; Thalassemia
  
• Cooperative Study of The Clinical Course of Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00005277 - Completed
  Anemia, Sickle Cell; Blood Disease
  
• Hemostasis in Sickle Cell Disease--Infancy to Adulthood
  ClinicalTrials.gov Identifier: NCT00005703 - Completed
  Anemia, Sickle Cell; Blood Disease
  
• Indices of Severity and Prognosis for Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00005467 - Completed
  Anemia, Sickle Cell; Blood Disease
  
• Cerebrovascular Involvement in Sickle Cell Disease - Comprehensive Sickle Cell Center
  ClinicalTrials.gov Identifier: NCT00005326 - Completed
  Anemia, Sickle Cell; Blood Disease; Cerebrovascular Accident
  
• Home Based Massage and Relaxation for Sickle Cell Pain
  ClinicalTrials.gov Identifier: NCT00066079 - Active, not recruiting
  Sickle Cell Disease
  
• Neuropsychological Studies of Children with Sickle Cell
  ClinicalTrials.gov Identifier: NCT00005438 - Completed
  Blood Disease; Anemia, Sickle Cell; Neurologic Manifestations
  
• Penicillin Prophylaxis in Sickle Cell Disease (PROPS)
  ClinicalTrials.gov Identifier: NCT00000585 - Completed
  Anemia, Sickle Cell; Hematologic Diseases; Hemoglobinopathies; Infection (S. pneumoniae); Pneumonia
  
• A Study Evaluating the Long-Term Safety of ICA-17043 in Sickle Cell Disease Patients With or Without Hydroxyurea Therapy
  ClinicalTrials.gov Identifier: NCT00294541 - Terminated
  Sickle Cell Disease; Sickle Cell Anemia
  
• Analysis of T-Cell Immune Reconstitution Following Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease (ImmuneReconstSCD)
  ClinicalTrials.gov Identifier: NCT00228631 - Recruiting
  Sickle Cell Disease
  
• Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload
  ClinicalTrials.gov Identifier: NCT00235391 - Active, not recruiting
  Thalassemia; Sickle Cell Disease; Diamond Blackfan Anemia; Myelofibrosis
  
• A 1-Year Extension Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Effects on Liver Iron Concentration of Deferasirox and Deferoxamine in Children and Adults With Sickle Cell Disease and Transfusional Hemosiderosis
  ClinicalTrials.gov Identifier: NCT00171197 - Active, not recruiting
  Sickle Cell Disease
  
• Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders
  ClinicalTrials.gov Identifier: NCT00005893 - Completed
  Neutropenia; Sickle Cell Anemia; Thalassemia Major; Red-Cell Aplasia, Pure
  
• Prevention Of Morbidity In Sickle Cell Disease Pilot Phase
  ClinicalTrials.gov Identifier: NCT00415727 - Recruiting
  Sickle Cell Anaemia
  
• Bone Marrow transplant from related donor for patients with high risk hemoglobinopathies
  ClinicalTrials.gov Identifier: NCT00040469 - Terminated
  Sickle Cell Anemia; Hemoglobinopathy; Thalassemia
  
• Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed By Donor Bone Marrow Transplant in Treating Patients With Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00489281 - Recruiting
  Precancerous/Nonmalignant Condition
  
• Inhaled Nitric Oxide for Pediatric Painful Sickle Crisis
  ClinicalTrials.gov Identifier: NCT00142051 - Recruiting
  Sickle Cell Disease
  
• Assessment of Opioid Analgesia in Sickle Cell
  ClinicalTrials.gov Identifier: NCT00513864 - Recruiting
  Sickle Cell Disease
  
• SALT: Alternative Donor Bone Marrow and Cord Blood Transplantation for High Risk Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00257543 - Recruiting
  Patients With Severe Sickle Cell Disease
  
• Bone marrow transplant from donor using less toxic conditioning for patient with high risk hemoglobinopathies
  ClinicalTrials.gov Identifier: NCT00040417 - Terminated
  Sickle Cell Anemia; Hemoglobinopathy; Thalassemia
  
• Steroid Treatment for Sickle Cell Pain Crisis
  ClinicalTrials.gov Identifier: NCT00263562 - Recruiting
  Sickle Cell Disease; Vaso-Occlusive Crisis
  
• Long Term Effects of Hydroxyurea Therapy in Children With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00305175 - Recruiting
  Sickle Cell Disease
  
• Evaluation of the Prevalence of Pulmonary Hypertension in Adult Patients With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00434902 - Recruiting
  Sickle Cell Disease
  
• A Phase 2 Study of the Effects of 6R-BH4 in Subjects With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00445978 - Recruiting
  Sickle Cell Disease
  
• Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00393250 - Recruiting
  Sickle Cell Disease
  
• Niacin to Improve Blood Flow in People With Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00508989 - Recruiting
  Sickle Cell Disease
  
• Transfusion Alternatives Pre-Operatively in Sickle Cell Disease (TAPS)
  ClinicalTrials.gov Identifier: NCT00512577 - Recruiting
  Sickle Cell Disease
  
• Allogeneic Bone Marrow Transplantation for the Treatment of Genetic Disorders of Erythropoiesis
  ClinicalTrials.gov Identifier: NCT00578435 - Recruiting
  Genetic Disorders; Sickle Cell Anemia
  
• Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients with Hemoglobinopathies
  ClinicalTrials.gov Identifier: NCT00153985 - Recruiting
  Hemoglobinopathies; Sickle Cell Disease; Thalassemia
  
• Pain Management Protocol for Pediatric Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00386048 - Recruiting
  Sickle Cell Disease
  
• Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia
  ClinicalTrials.gov Identifier: NCT00005896 - Active, not recruiting
  Fanconi's Anemia
  
• Simvastatin (Zocor) Therapy in Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00508027 - Recruiting
  Sickle Cell Disease
  
• Cord Blood Stem Cell Transplantation Study (COBLT)
  ClinicalTrials.gov Identifier: NCT00000603 - Active, not recruiting
  Anemia, Aplastic; Fanconi Anemia; Hematologic Diseases; Leukemia; Neoplasms; Severe Combined Immunodeficiency; ...
  
• Kid Cards: Teaching Kids About Medicines
  ClinicalTrials.gov Identifier: NCT00127543 - Active, not recruiting
  Hemophilia; Sickle Cell Disease; Neoplasm; Blood Coagulation Disorders
  
• Stem Cell Transplant in Sickle Cell Disease and Thalassemia
  ClinicalTrials.gov Identifier: NCT00408447 - Recruiting
  Sickle Cell Disease; Beta Thalassemia