This study will determine whether a therapeutic exercise program for improving motor coordination in locomotor tasks in post-stroke, hemiparesis patients will result in CNS recovery. The study will develop relationships between the improved motor performance and motor coordination during the locomotor task and the functional effects of the exercise program(e.g., gait variables.)

Condition	Treatment or Intervention	Phase
Stroke	Procedure: Stroke Rehabilitation	Phase II

Further Study Details: 

Expected Total Enrollment:  70

Primary objective of this study is to determine whether a therapeutic exercise program which targets the functional recovery of persons with the post-stroke hemiparesis results in CNS recovery (improved motor coordination). They will determine whether motor coordination during a locomotor task is improved after an exercise program. They will then develop relationships between the improved motor performance and motor coordination during the locomotor task and the functional effects of the exercise program(e.g., gait variables) Overall goal is to develop a more rational basis for the design of stroke rehabilitation programs which target individuals most likely to recover and which are based on physiological principles. This study will supplement an NIH funded randomized clinical trial to evaluate a post-stroke exercise program designed to increase balance, strength, and endurance. Study will include 60-70 prospective patients enrolled in the randomized clinical trial at Kansas University Center on Aging. between Oct 1999 and Oct 2001.

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both

Criteria

Functionally impaired elderly

Kansas
      VAMC, Kansas City, Kansas City,  Kansas,  United States

Study chairs or principal investigators

John Fryer, Ph.D., Asst. Director,  Department of Veterans Affairs, Program Analysis and Review Section (PARS), Rehabilitation Research & Development Service   
Victoria Mongiardo, Program Analyst,  Department of Veterans Affairs, Program Analysis and Review Section (PARS), Rehabilitation Research & Development Service   

Study ID Numbers:  E2116
Record last reviewed:  January 2001
Last Updated:  October 13, 2004
Record first received:  March 14, 2001
ClinicalTrials.gov Identifier:  NCT00013481
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08