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Quality of Life of Adult Cancer Survivors Who Have Undergone a Previous Bone Marrow or Peripheral Stem Cell Transplant for a Childhood Hematologic Cancer - Article


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Clinical Trial: Quality of Life of Adult Cancer Survivors Who Have Undergone a Previous Bone Marrow or Peripheral Stem Cell Transplant for a Childhood Hematologic Cancer

This study is currently recruiting patients.
Verified by National Cancer Institute (NCI) July 2005

Sponsors and Collaborators: Fred Hutchinson Cancer Research Center
National Cancer Institute (NCI)
Information provided by: National Cancer Institute (NCI)
ClinicalTrials.gov Identifier: NCT00126477

Purpose

RATIONALE: Studying quality of life in cancer survivors may help determine the long-term effects of hematologic cancer and may help improve the quality of life for future cancer survivors.

PURPOSE: This clinical trial is studying the quality of life of adult cancer survivors who have undergone a previous bone marrow or peripheral stem cell transplant for a childhood hematologic cancer.

Condition Intervention Phase
childhood Hodgkin''''s lymphoma
childhood non-Hodgkin''''s lymphoma
Leukemia
Quality of Life
 Procedure: cognitive assessment
 Procedure: complications of therapy assessment/management
 Procedure: psychosocial assessment/care
 Procedure: quality-of-life assessment
 Procedure: supportive care/therapy
Phase II

MedlinePlus related topics:  Hodgkin''''s Disease;   Leukemia, Adult Acute;   Leukemia, Adult Chronic;   Leukemia, Childhood;   Lymphoma

Study Type: Interventional
Study Design: Treatment

Official Title: Phase II Study of Quality of Life of Adult Cancer Survivors Who Have Undergone Prior Bone Marrow or Peripheral Blood Stem Cell Transplantation for a Pediatric Hematologic Malignancy

Further Study Details: 

OBJECTIVES:

OUTLINE: Patients and siblings complete a self-report quality of life questionnaire, including outcome assessments of neuroendocrine function, cognitive abilities, physical capability, and psychosocial behavior.

PROJECTED ACCRUAL: Approximately 750 patients (375 adult cancer survivors [case group] and 375 siblings [control group]) will be accrued for this study within 7 years.

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both
Criteria

DISEASE CHARACTERISTICS:

  • Case group
  • Previously treated with an allogeneic, unrelated, syngeneic, or autologous bone marrow or peripheral blood stem cell transplantation for a hematologic malignancy ≥ 5 years ago while enrolled on 1 of the following protocols:
  • FHCRC-179.07T
  • FHCRC-446.03T
  • FHCRC-661.04
  • FHCRC-697.00
  • FHCRC-796.00
  • FHCRC-843.00
  • Disease-free survivor
  • Under 18 years of age at time of transplantation
  • Any prior preparative regimen allowed
  • Control group
  • Sex-matched sibling within 5 years of patient''''s age*
  • No chronic illnesses (e.g., cancer, diabetes, or asthma) that require medication
  • No allergies that limit physical activity NOTE: *If such a sibling is not available, but another sibling is available, then that sibling would be asked to nominate a friend or relative of the same gender as the patient who is also within 5 years of the patient''''s age; the patient must consent in order for the control subject to participate

PATIENT CHARACTERISTICS:

Age

  • See Disease Characteristics
  • 18 and over

Performance status

  • Not specified

Life expectancy

  • Not specified

Hematopoietic

  • Not specified

Hepatic

  • Not specified

Renal

  • Not specified

Other

  • Must be able to speak, read, and write English

PRIOR CONCURRENT THERAPY:

Biologic therapy

  • See Disease Characteristics

Chemotherapy

  • Not specified

Endocrine therapy

  • Not specified

Radiotherapy

  • Not specified

Surgery

  • Not specified

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00126477


Washington
      Fred Hutchinson Cancer Research Center, Seattle,  Washington,  98109-1024,  United States; Recruiting
Jean E. Sanders, MD  206-667-4348    jsanders@fhcrc.org 

Study chairs or principal investigators

Jean E. Sanders, MD,  Principal Investigator,  Fred Hutchinson Cancer Research Center   

More Information

Clinical trial summary from the National Cancer Institute''''s PDQ® database

Study ID Numbers:  CDR0000434793; FHCRC-1098.00
Last Updated:  August 9, 2005
Record first received:  August 2, 2005
ClinicalTrials.gov Identifier:  NCT00126477
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-08-23


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August 29, 2008



Page Updated: November 22, 2004
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