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Indoor Environmental Quality |
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Clinical Trial: Does Menopause Matter?
This study is currently recruiting patients.
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Purpose
The purpose of this study is to follow a woman’s progression through menopause in order to examine the effects on health related quality of life and use of health care resources, and to understand how women are using alternative therapies.
| Condition |
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| Menopause Quality of Life |
MedlinePlus consumer health information
Study Type: Observational
Study Design: Psychosocial, Longitudinal, Defined Population, Prospective Study
Expected Total Enrollment: 720
Study start: December 2004; Expected completion: July 2009
Last follow-up: January 2009; Data entry closure: January 2009
Menopause affects every woman as she ages, yet every woman’s experience is different. We are seeking to enroll 720 women from the University of Pittsburgh’s Division of General Internal Medicine Outpatient practice (GIMO) at all stages of menopause (pre-, peri-, and post-menopausal), between 40 and 65 years old. They will be followed for 5 years as they progress through menopause.
Women will complete yearly questionnaires during their usual doctor’s visit (or by phone or online if necessary) regarding general health, menopause and menopausal symptoms, health related quality of life, traditional and alternative therapy use, social support, and attitudes towards menopause and aging.
We will combine this information with information from women’s medical charts to look at how menopause and health related quality of life impact the use of health care resources. Additionally, some women may be asked about the use of health care resources, such as doctor’s visits, hospitalizations and lab tests.
Eligibility
Ages Eligible for Study: 40 Years - 65 Years, Genders Eligible for Study: Female
Accepts Healthy Volunteers
Criteria
Inclusion Criteria:
- Women ages 40-65
- Patient in the University of Pittsburgh General Internal Medicine Oakland Practice
- Able to complete our Functional Assessment Screening Tablet (a touch-screen survey)
Exclusion Criteria:
- Refusal to participate
Location and Contact Information
Pennsylvania
UPMC General Internal Medicine Oakland, Pittsburgh, Pennsylvania, 15213, United States; Recruiting
Rachel Hess, MD, MSc, Principal Investigator
Wishwa Kapoor, MD, MPH, Sub-Investigator
Karen Matthews, PhD, Sub-Investigator
Roberta Ness, MD, MPH, Sub-Investigator
Rachel Hess, MD, MSc, Principal Investigator, UPMC General Internal Medicine-Oakland
More Information
Publications
Hlatky MA, Boothroyd D, Vittinghoff E, Sharp P, Whooley MA; Heart and Estrogen/Progestin Replacement Study (HERS) Research Group. Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy: results from the Heart and Estrogen/Progestin Replacement Study (HERS) trial. JAMA. 2002 Feb 6;287(5):591-7.
Avis NE, Ory M, Matthews KA, Schocken M, Bromberger J, Colvin A. Health-related quality of life in a multiethnic sample of middle-aged women: Study of Women's Health Across the Nation (SWAN). Med Care. 2003 Nov;41(11):1262-76.
Gambacciani M, Ciaponi M, Cappagli B, Monteleone P, Benussi C, Bevilacqua G, Genazzani AR. Effects of low-dose, continuous combined estradiol and noretisterone acetate on menopausal quality of life in early postmenopausal women. Maturitas. 2003 Feb 25;44(2):157-63.
Albertazzi P, Purdie D. The nature and utility of the phytoestrogens: a review of the evidence. Maturitas. 2002 Jul 25;42(3):173-85. Review.
Record last reviewed: March 2005
Last Updated: March 1, 2005
Record first received: December 1, 2004
ClinicalTrials.gov Identifier: NCT00097994
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
Resources
- Indoor Environmental Quality (Centers for Disease Control and Prevention)

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