Salmonella typhi Infection |
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Clinical Trial: Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients
This study has been completed.
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Purpose
To compare the effectiveness of standard treatment with parenteral ampicillin and oral amoxicillin compared to initial daily therapy with ceftriaxone followed by 3 times weekly suppressive treatment for salmonella infections in AIDS patients.
| Condition | Treatment or Intervention |
|---|---|
| HIV Infections Salmonella Infections | Drug: Ceftriaxone sodium Drug: Ampicillin sodium Drug: Amoxicillin trihydrate |
MedlinePlus related topics: AIDS; Salmonella Infections
Study Type: Interventional
Study Design: Treatment, Dose Comparison
Eligibility
Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both
Criteria
Exclusion Criteria
Co-existing Condition: Patients with the following are excluded:
- Type I hypersensitivity to beta-lactam antibiotics.
- Not expected to survive 12 weeks.
- In a coma or with other central nervous system (CNS) impairment.
Patients with the following are excluded:
- Type I hypersensitivity to beta-lactam antibiotics.
- Not expected to survive 12 weeks.
- In a coma or with other central nervous system (CNS) impairment.
Prior Medication: Excluded within 48 hours of study entry:
- Treatment with an antibiotic active in vitro against Salmonella.
HIV infection, AIDS, or AIDS related complex (ARC).
- Salmonella bacteremia or positive stool culture in patient with 3 or more stools per day.
Location Information
California
Los Angeles County - USC Med Ctr, Los Angeles, California, 90033, United States
More Information
Record last reviewed: August 1989
Last Updated: October 13, 2004
Record first received: November 2, 1999
ClinicalTrials.gov Identifier: NCT00002052
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005

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