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Statistical Analysis of Pediatric Task Force Data Base - Article


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Statistical Analysis Battery for Epidemiological Research

SABER


Clinical Trial: Statistical Analysis of Pediatric Task Force Data Base

This study has been completed.

Sponsored by: National Heart, Lung, and Blood Institute (NHLBI)
Information provided by: National Heart, Lung, and Blood Institute (NHLBI)

Purpose

To define pediatric sex-specific blood pressure percentiles that were a function of both age and height. Also, to define the precise age at which blood pressure distributions for different racial groups diverged.

Condition
Cardiovascular Diseases
Heart Diseases
Hypertension

MedlinePlus related topics:  Heart Diseases;   Heart Diseases--Prevention;   High Blood Pressure;   Vascular Diseases

Study Type: Observational
Study Design: Natural History

Further Study Details: 

Study start: February 1991;  Study completion: January 1993

BACKGROUND: Hypertension is a well-recognized risk factor for cardiovascular disease in adults. Furthermore, many studies have shown that there is tracking among longitudinal pediatric blood pressure determinations. An important unresolved goal in pediatric hypertension research is to define at what level of pediatric blood pressure is a child at increased risk for adult hypertension. When the grant was awarded in February 1991, there had been two NHLBI Task Forces in Blood Pressure Control in Children which had published reports in 1977 and 1987. One of the goals of each task force was to define appropriate percentiles for blood pressure in children. In the Second Task Force Report, results from nine large epidemiologic studies were combined into a data base with more than 70,000 readings from which blood pressure percentiles were derived as a function of age and sex. However, many research workers stated that height is more strongly related to blood pressure than age and have urged that Normative data for pediatric blood pressure be demarcated by height rather than age.

DESIGN NARRATIVE: Blood pressure percentiles were constructed that were a function of age, sex, race, and height, thus providing a more comprehensive profile of pediatric blood pressure distributions than any previously published work.

Eligibility

Genders Eligible for Study:  Male

Criteria

No eligibility criteria

More Information

Study ID Numbers:  4324
Record last reviewed:  May 2000
Last Updated:  October 13, 2004
Record first received:  May 25, 2000
ClinicalTrials.gov Identifier:  NCT00005407
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005


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October 11, 2008



Page Updated: November 22, 2004
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