Genetic Brain Disorders |
BCKD deficiency; Brain Disorders, Inborn Genetic; Branched-chain alpha-keto acid dehydrogenase deficiency; Branched-Chain Ketoaciduria; Ketoacidemia; Maple Syrup Urine Disease; MSUD |
Maple syrup urine disease (MSUD) is an autosomal recessive metabolic disorder due to a deficiency of decarboxylase enzyme that leads to elevated concentrations of leucine, isoleucine, and valine (branched amino acids) in the blood and urine. Characterized by the urine having an odor similar to that of maple syrup. This results in severe mental retardation, and seizures. Because of a genetic bottleneck effect, MSUD has a much higher prevalence in children of Mennonite descent. Also called br ...
Wikipedia - [full article]
Genetic Brain Disorders Clinical Trials
- Genetic Analysis of Brain Disorders
ClinicalTrials.gov Identifier: NCT00341978 - Recruiting
Brain Disorders
- Allogeneic Bone Marrow Transplantation for the Treatment of Genetic Disorders of Erythropoiesis
ClinicalTrials.gov Identifier: NCT00578435 - Recruiting
Genetic Disorders; Sickle Cell Anemia
- Sedation During Microelectrode Recordings Before Deep Brain Stimulation for Movement Disorders.
ClinicalTrials.gov Identifier: NCT00355927 - Enrolling by invitation
Movement Disorders; Parkinson Disease; Parkinsonian Disorders; Dystonia; Tourette Syndrome
- Perfusion Magnetic Resonance Imaging in Measuring the Growth of Blood Vessels in Newly Diagnosed Brain Tumors
ClinicalTrials.gov Identifier: NCT00005790 - Active, not recruiting
genetic condition; Cancer; adult brain tumor; Brain Tumor; stage/type, adult brain tumor; body system/site cancer; central nervous system cancer; ...
- Brain Imaging and Mental Disorders of Aging Intervention
ClinicalTrials.gov Identifier: NCT00267163 - Active, not recruiting
Cognition Disorders
- Genetic Study in Patients Receiving Treatment for Hodgkin's Disease or Childhood Brain Tumor
ClinicalTrials.gov Identifier: NCT00006342 - Active, not recruiting
Lymphoma; Brain Tumor
- Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00008086 - Active, not recruiting
Brain Tumor; Genetic Condition; Solid Tumor
- Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease
ClinicalTrials.gov Identifier: NCT00368446 - Recruiting
Mycobacteria, Atypical; Cystic Fibrosis; Ciliary Disorders; Pseudohypoaldosteronism; Bronchiectasis
- A Trial of Two On-Line Interventions for Child Brain Injury
ClinicalTrials.gov Identifier: NCT00178022 - Active, not recruiting
Traumatic Brain Injury; Depression; Anxiety Disorders
- Brain Changes in Stimulant Dependent Subjects - 8
ClinicalTrials.gov Identifier: NCT00000343 - Active, not recruiting
Substance-Related Disorders
- Retrospective Review of the Outcomes of Newborns With Genetic Abnormalities
ClinicalTrials.gov Identifier: NCT00366821 - Active, not recruiting
Congenital Disorders
- Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
ClinicalTrials.gov Identifier: NCT00262288 - Active, not recruiting
Genetic Disorders
- Reward-Related Processes and Brain Function
ClinicalTrials.gov Identifier: NCT00029588 - Active, not recruiting
Depression; Anxiety Disorders; Healthy
- Studies of Children with Metabolic and Other Genetic Disorders
ClinicalTrials.gov Identifier: NCT00025870 - Recruiting
Genetic Disorder; Metabolic Disease
- Combining Behavioral Treatment with Agonist Maintenance - 1
ClinicalTrials.gov Identifier: NCT00000311 - Active, not recruiting
Cocaine-Related Disorders; Opioid-Related Disorders; Substance-Related Disorders
- The Effects of Pharmacotherapy on Brain Mechanisms Underlying Cocaine Dependence.
ClinicalTrials.gov Identifier: NCT00396734 - Recruiting
Opioid-Related Disorders; Cocaine-Related Disorders
- Integrated Treatment to Persons With Mental Disorders and co-Occurring Substance Use Disorders
ClinicalTrials.gov Identifier: NCT00447733 - Recruiting
Anxiety Disorders; Mood Disorders; Substance Use Disorders
- Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement
ClinicalTrials.gov Identifier: NCT00056420 - Recruiting
Tourette Syndrome; Tic Disorders
- A Pilot Study of Boredom in a Community Sample of Adolescents and a Clinical Sample of Adolescents
ClinicalTrials.gov Identifier: NCT00163865 - Recruiting
Mental Disorders; Affective Disorders; Anxiety Disorders; Attention Deficit and Disruptive Behavior Disorders; Psychotic Disorders
- Brain Changes in Fear
ClinicalTrials.gov Identifier: NCT00047853 - Recruiting
Anxiety Disorders
- Central Auditory Processing Disorders Associated With Blast Exposure
ClinicalTrials.gov Identifier: NCT00554801 - Recruiting
Central Auditory Processing Disorders; Traumatic Brain Injury; Hearing Loss
- Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
ClinicalTrials.gov Identifier: NCT00262301 - Recruiting
Genetic Disorders
- Rare Genetic Disorders of the Breathing Airways
ClinicalTrials.gov Identifier: NCT00323167 - Recruiting
Kartagener Syndrome; Cystic Fibrosis; Pseudohypoaldosteronism; Primary Ciliary Dyskinesia
- Treatment of Citalopram for Anxiety Disorders Following a Traumatic Brain Injury
ClinicalTrials.gov Identifier: NCT00208572 - Recruiting
Traumatic Brain Injury
- Brain Mapping of Voice Control
ClinicalTrials.gov Identifier: NCT00066911 - Recruiting
Voice Disorders
- Family Intervention for Mental Illness and Substance Abuse
ClinicalTrials.gov Identifier: NCT00043693 - Active, not recruiting
Mental Disorders; Substance-Related Disorders; Psychotic Disorders
- Brain Activity in People With Functional Movement Disorders
ClinicalTrials.gov Identifier: NCT00448084 - Recruiting
Functional Movement Disorders
- Child and Adolescent Anxiety Disorders (CAMS)
ClinicalTrials.gov Identifier: NCT00052078 - Active, not recruiting
Anxiety Disorders
- Therapeutic Processes and Treatment Outcome in Adolescents with Anxiety Disorders
ClinicalTrials.gov Identifier: NCT00071630 - Active, not recruiting
Anxiety Disorders
- MRI Study of Brain Activity and Risk for Depression in Adolescents
ClinicalTrials.gov Identifier: NCT00047944 - Recruiting
Involutional Depression; Anxiety Disorders
- MR Guided Laser Interstitial Thermal Therapy for the “Minimal Invasive” Treatment of Brain Metastasis
ClinicalTrials.gov Identifier: NCT00392119 - Recruiting
Brain Neoplasms; Brain Tumor; Brain Cancer; Recurrent Brain Tumor
- Pharmacotherapy and Intensive Treatment - 2
ClinicalTrials.gov Identifier: NCT00000218 - Active, not recruiting
Cocaine-Related Disorders; Substance-Related Disorders
- Measuring Head Impacts in Sports
ClinicalTrials.gov Identifier: NCT00060827 - Active, not recruiting
Brain Injuries; Brain Concussion
- Brain Function of Self-Regulation in Women With Bulimia Nervosa
ClinicalTrials.gov Identifier: NCT00345943 - Recruiting
Eating Disorders
- Methylphenidate in the Treatment of Cocaine Dependent Patients with Adult Attention Deficit Hyperactivity Disorder - 5
ClinicalTrials.gov Identifier: NCT00015223 - Active, not recruiting
Cocaine-Related Disorders; Substance-Related Disorders
- Genetic Study of Cancer Risk and Gene Identification in Patients With Inherited Bone Marrow Disorders and Their Families
ClinicalTrials.gov Identifier: NCT00056121 - Recruiting
Cancer
- Buprenorphine Maintenance Dose Schedule and Treatment Setting - 1
ClinicalTrials.gov Identifier: NCT00000318 - Active, not recruiting
Opioid-Related Disorders; Substance-Related Disorders
- Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders
ClinicalTrials.gov Identifier: NCT00582621 - Recruiting
Lymphoma; Leukemia; Multiple Myeloma; Colon Cancer; Renal Cancer
- The Effectiveness of Regular Exercise on Improving Sleep in Older Adults
ClinicalTrials.gov Identifier: NCT00149747 - Active, not recruiting
Sleep Initiation and Maintenance Disorders; Sleep Disorders, Intrinsic
- Phase II Randomized Study of Stereotactic Radiosurgery Plus Fractionated Whole-Brain Radiotherapy vs Fractionated Whole-Brain Radiotherapy Alone for Multiple Primary or Metastatic Brain Tumors
ClinicalTrials.gov Identifier: NCT00004659 - Active, not recruiting
Brain Neoplasms
- Study of Karenitecin (BNP1350) in Patients with Brain Tumors
ClinicalTrials.gov Identifier: NCT00062478 - Active, not recruiting
Brain Neoplasms; Malignant Neoplasms, Brain; Brain Tumors
- Effectiveness of Cognitive-Affective Behavior Therapy for the Treatment of Somatization Disorder
ClinicalTrials.gov Identifier: NCT00149760 - Active, not recruiting
Anxiety Disorders; Somatoform Disorders
- Substance Dependent Teens - Impact of Treating Depression Study 1 - 1
ClinicalTrials.gov Identifier: NCT00061113 - Active, not recruiting
Alcohol-Related Disorders; Marijuana Abuse; Substance-Related Disorders
- The BRAIN ICU Study: Bringing to Light the Risk Factors
ClinicalTrials.gov Identifier: NCT00392795 - Recruiting
Delirium; Cognition Disorders; Dementia
- Sleep Disorders Management, Health and Safety in Police
ClinicalTrials.gov Identifier: NCT00207285 - Recruiting
Sleep Disorders; Sleep Apnea, Obstructive; Restless Legs Syndrome; Sleep Disorders, Circadian Rhythm; Sleep Initiation and Maintenance Disorders
- Antidepressant Safety in Kids (ASK) Study
ClinicalTrials.gov Identifier: NCT00395213 - Recruiting
Anxiety Disorders; Depressive Disorders; Eating Disorders; Obsessive Compulsive Disorder
- Antineoplaston Therapy in Treating Patients With Brain Stem Glioma
ClinicalTrials.gov Identifier: NCT00003459 - Active, not recruiting
recurrent adult brain tumor; adult brain stem glioma; untreated childhood brain stem glioma; recurrent childhood brain stem glioma
- Resource-Oriented Music Therapy for Psychiatric Patients with Low Therapy Motivation
ClinicalTrials.gov Identifier: NCT00137189 - Recruiting
Mental Disorders; Mood Disorders; Personality Disorders; Schizophrenia and Disorders with Psychotic Features
- Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma
ClinicalTrials.gov Identifier: NCT00360854 - Active, not recruiting
Brain and Central Nervous System Tumors
- Detection of Ultrasound Contrast Signals in the Cerebral Circulation
ClinicalTrials.gov Identifier: NCT00579241 - Recruiting
Brain Vascular Disorders; Coronary Artery Disease
- Effectiveness of Disulfiram and Naltrexone Used in Combination to Treat Individuals Diagnosed with Both Cocaine and Alcohol Dependence - 1
ClinicalTrials.gov Identifier: NCT00142844 - Active, not recruiting
Alcohol-Related Disorders; Alcoholism; Cocaine-Related Disorders
- Genetic Analysis of Brain Tumors
ClinicalTrials.gov Identifier: NCT00031538 - Recruiting
Glioma
- The Immune System and Psychiatric Disorders
ClinicalTrials.gov Identifier: NCT00184418 - Active, not recruiting
Stress; Depression; Mania; Personality Disorders; Schizophrenia
- A Laboratory Model for Heroin Abuse Medications - 8
ClinicalTrials.gov Identifier: NCT00000273 - Active, not recruiting
Heroin Dependence; Opioid-Related Disorders; Substance-Related Disorders
- Place of Low-Dose Naltrexone in Opiate Detoxification - 1
ClinicalTrials.gov Identifier: NCT00135759 - Active, not recruiting
Heroin Dependence; Opioid-Related Disorders; Substance-Related Disorders
- Study of Motexafin Gadolinium with Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients with Brain Metastases
ClinicalTrials.gov Identifier: NCT00121420 - Active, not recruiting
Neoplasm Metastasis; Brain Neoplasms
- Effects of an Alternative Treatment for Military Sexual Trauma on PTSD Symptoms, Neurosteroids and Brain Function
ClinicalTrials.gov Identifier: NCT00374738 - Recruiting
Stress Disorders
- hCRF for Patients Requiring Dexamethasone to Treat Peritumoral Brain Edema Associated with Primary Malignant Glioma
ClinicalTrials.gov Identifier: NCT00226668 - Recruiting
Brain Edema; Brain Tumor
- Family Psychoeducation for Children with Mood Disorders
ClinicalTrials.gov Identifier: NCT00050557 - Active, not recruiting
Mood Disorders
- Human Corticotropin-Releasing Factor (hCRF) for Patients Requiring Chronic High-Doses of Dexamethasone to Treat Edema Associated with Malignant Brain Tumors
ClinicalTrials.gov Identifier: NCT00088166 - Recruiting
Brain Edema; Brain Tumor
- Nefazodone in the Treatment of Cocaine Dependence and Depression - 4
ClinicalTrials.gov Identifier: NCT00015210 - Active, not recruiting
Cocaine-Related Disorders; Substance-Related Disorders
- A study of Cabergoline for the Treatment of Cocaine Dependence - 1
ClinicalTrials.gov Identifier: NCT00033111 - Active, not recruiting
Cocaine-Related Disorders; Substance-Related Disorders
- Treatment of Alcoholism with Cocaine Dependence
ClinicalTrials.gov Identifier: NCT00136162 - Active, not recruiting
Alcoholism; Alcohol-Related Disorders; Cocaine-Related Disorders
- Temozolomide in Treating Patients With Solid Tumors That Have Spread to the Brain
ClinicalTrials.gov Identifier: NCT00012116 - Active, not recruiting
brain metastases
- Women's Treatment for Trauma and Substance Use Disorders - 1
ClinicalTrials.gov Identifier: NCT00078156 - Active, not recruiting
Substance-Related Disorders
- Effectiveness of Escitalopram in the Treatment of Body Dysmorphic Disorder
ClinicalTrials.gov Identifier: NCT00149799 - Recruiting
Anxiety Disorders; Somatoform Disorders
- Family Study of Affective and Anxiety Spectrum Disorders
ClinicalTrials.gov Identifier: NCT00071786 - Recruiting
Mood DIsorders; Anxiety Disorders
- Early Phase II Trials for Cocaine Medication Development - 1
ClinicalTrials.gov Identifier: NCT00000317 - Active, not recruiting
Cocaine-Related Disorders; Substance-Related Disorders
- Study of Systemic and Spinal Chemotherapy Followed by Radiation for Infants with Brain Tumors
ClinicalTrials.gov Identifier: NCT00042367 - Active, not recruiting
Brain Tumors
- Reserpine for the Treatment of Cocaine Dependence - 1
ClinicalTrials.gov Identifier: NCT00033033 - Active, not recruiting
Cocaine-Related Disorders; Substance-Related Disorders
- Assessment of Potential Interactions between Cocaine and RPR 102681 - 1
ClinicalTrials.gov Identifier: NCT00067535 - Active, not recruiting
Cocaine-Related Disorders
- Deep Brain Stimulation to Treat Symptoms of Parkinson's Disease
ClinicalTrials.gov Identifier: NCT00552474 - Recruiting
Parkinson Disease; Movement Disorders
- Side Effects of Antipsychotic Medications
ClinicalTrials.gov Identifier: NCT00363181 - Recruiting
Insulin Resistance; Metabolic Syndrome X; Schizophrenia and Disorders With Psychotic Features; Mood Disorders; Psychotic Disorders
- Evaluating the Benefits and Affordability of a Program to Improve the Care of Common Mental Disorders in Primary Care
ClinicalTrials.gov Identifier: NCT00446407 - Recruiting
Depressive Disorders; Anxiety Disorders; Depression
- Study of the Effect of Imagery Rehearsal Treatment (IRT) of Nightmares
ClinicalTrials.gov Identifier: NCT00291031 - Recruiting
Nightmares; Anxiety Disorders; Mood Disorders; Personality Disorders
- Gene Therapy for the Treatment of Brain Tumors
ClinicalTrials.gov Identifier: NCT00001328 - Active, not recruiting
Brain Neoplasm; Neoplasm Metastasis
- Supporting Traumatic Brain Injury (TBI) Caregivers
ClinicalTrials.gov Identifier: NCT00006447 - Active, not recruiting
Traumatic Brain Injuries
- Short- and Long-Term Group Psychotherapy
ClinicalTrials.gov Identifier: NCT00521417 - Recruiting
Non-Psychotic Affective Disorders.; Non-Psychotic Anxiety Disorders.; Personality Disorders.
- Telephone Care as a Substitute for Routine Psychiatric Medication Management
ClinicalTrials.gov Identifier: NCT00105885 - Active, not recruiting
Major Depressive Disorder; Post-Traumatic Stress Disorders; Anxiety Disorders
- Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
ClinicalTrials.gov Identifier: NCT00030628 - Active, not recruiting
brain metastases
- Body Cooling for Birth Asphyxia in Term Infants
ClinicalTrials.gov Identifier: NCT00005772 - Active, not recruiting
Hypoxic-Ischemic Encephalopathy; Asphyxia; Brain Ischemia; Hypoxia, Brain
- Evaluation and Treatment of Neurosurgical Disorders
ClinicalTrials.gov Identifier: NCT00060541 - Recruiting
Neurologic Disorders
- A Study on Evaluation of Mental Health Index of Patients with Psychiztric Disorders
ClinicalTrials.gov Identifier: NCT00166764 - Recruiting
Psychiatric Disorders
- Evaluating the Effectiveness of Early Cognitive Behavioral Therapy With or Without Parental Involvement in Treating Children With Anxiety Disorders
ClinicalTrials.gov Identifier: NCT00557648 - Active, not recruiting
Anxiety Disorders
- Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children
ClinicalTrials.gov Identifier: NCT00218777 - Active, not recruiting
Tourette Syndrome; Tic Disorders
- Noninvasive Prenatal Diagnosis: Using Fetal Cells from Maternal Blood
ClinicalTrials.gov Identifier: NCT00064597 - Active, not recruiting
Chromosome Disorders
- Lithium and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Primary Cancer Outside the Brain
ClinicalTrials.gov Identifier: NCT00469937 - Recruiting
Brain and Central Nervous System Tumors; Cognitive/Functional Effects; Neurotoxicity; Radiation Toxicity; Unspecified Adult Solid Tumor, Protocol Specific
- Genetic Analysis of Gray Platelet Syndrome
ClinicalTrials.gov Identifier: NCT00069680 - Recruiting
Genetic Linkage; Myelofibrosis
- Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders
ClinicalTrials.gov Identifier: NCT00494169 - Recruiting
Hypogonadism; Kallmann Syndrome; Puberty, Delayed; Puberty, Precocious; Hypothalamic Amenorrhea; Anosmia
- Detection and Characterization of Infections and Infection Susceptibility
ClinicalTrials.gov Identifier: NCT00404560 - Recruiting
Immune Disorders; Chronic Granulomatous Disease; Genetic Immunological Deficiencies; Hyperimmunoglobulin-E Recurrent Infection Syndrome; Recurrent Infections
- Bortezomib in Treating Patients With Advanced Myeloproliferative Disorders
ClinicalTrials.gov Identifier: NCT00437086 - Active, not recruiting
Chronic Myeloproliferative Disorders; Leukemia
- Interactions Between Cocaine and Ethanol and Disulfiram - 1
ClinicalTrials.gov Identifier: NCT00094289 - Active, not recruiting
Alcohol-Related Disorders; Cocaine-Related Disorders
- Thalomid and Carboplatin for the Treatment of Pediatric Brain Stem Glioma
ClinicalTrials.gov Identifier: NCT00179881 - Active, not recruiting
Brain Stem Neoplasms, Primary; Neoplasms, Brain Stem
- Clinical Trial of Integrated Treatment Versus Standard Treatment in First Episode Psychosis
ClinicalTrials.gov Identifier: NCT00157313 - Active, not recruiting
Psychotic Disorders; Schizophreniform Disorders; Schizoaffective Disorder; Psychosis, Brief Reactive; Schizophrenia, Borderline
- A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory Complaints
ClinicalTrials.gov Identifier: NCT00276510 - Active, not recruiting
Memory Disorders, Age-Related; Retention Disorders, Cognitive
- SU5416 in Treating Children With Recurrent or Progressive Brain Tumors
ClinicalTrials.gov Identifier: NCT00006247 - Active, not recruiting
Brain Cancer
- Study on Amino Acid Uptake in Brain Tumors
ClinicalTrials.gov Identifier: NCT00204295 - Active, not recruiting
Brain Neoplasms
- Measuring Blood Flow in the Brain
ClinicalTrials.gov Identifier: NCT00466934 - Active, not recruiting
Traumatic Brain Injury; Healthy
- Long-Term Analysis of Urea Cycle Disorders
ClinicalTrials.gov Identifier: NCT00237315 - Recruiting
Brain Diseases, Metabolic, Inborn; Amino Acid Metabolism, Inborn Errors
- Radiation Therapy With or Without Temozolomide in Treating Patients With Non-Small Cell Lung Cancer That is Metastatic to the Brain
ClinicalTrials.gov Identifier: NCT00030836 - Active, not recruiting
brain metastases

Not Signed In -


