This study will determine the effectiveness of guided self-help (GSH) treatment in treating individuals with binge eating disorder (BED).

Condition	Intervention
Eating Disorders Hyperphagia Bulimia	Behavior: Guided self-help  Behavior: Usual clinical care

Further Study Details: 

Primary Outcomes: Frequency of binge eating at baseline, Week 12, Month 6, and Month 12
Secondary Outcomes: Frequency of inappropriate compensatory behaviors, dietary restraint, overevaluation of weight/shape, functional impairment, self-esteem, and social impairment assessed at baseline, 12 weeks, 6 months, and 12 months; body weight assessed at baseline and 12 months
Expected Total Enrollment:  200

BED is a serious condition characterized by compulsive overeating and feelings of powerlessness. The condition often has a negative impact on both physical and emotional health. This study will examine ways to help people determine whether they have BED and will test whether GSH treatment is effective in treating BED.

Participants will be randomly assigned to receive either GSH treatment or usual clinical care (which may include general support and talk therapy) for 3 months. The GSH treatment is a cognitive behavioral therapy-based program that will be administered over 8 sessions. Participants receiving GSH will be given a book that focuses on dealing with BED; they will also meet with a therapist regularly to have their progress monitored. The Eating Disorders Examination (EDE), self-reports, questionnaires, and surveys will be used to assess participants. Assessments will be conducted at study entry, at Weeks 2 and 4 of the treatment, at the end of the treatment, and at 6 and 12 months post-treatment.

Ages Eligible for Study:  18 Years   -   50 Years,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

• Diagnosis of binge eating disorder (BED) bulimia nervosa (BN), or spectrum BN, defined as recurrent binge eating at least once a week for 3 months
• Body mass index (BMI) between 18 and 45
• Continuous membership in the Kaiser Permanente Northwest Division for at least 12 months prior to study entry

Exclusion Criteria:

• Diagnosis of anorexia nervosa or psychotic disorder
• Significant organic brain syndromes, retardation, pervasive developmental disorder, or autism
• At risk for suicide
• Pregnancy

Please refer to this study by ClinicalTrials.gov identifier  NCT00158340

Connecticut
      Wesleyan University Department of Psychology, Middletown,  Connecticut,  06459,  United States; Recruiting
Oregon
      Kaiser Permanente Center for Health Research, Portland,  Oregon,  97227,  United States; Recruiting

Study chairs or principal investigators

Ruth H. Striegel-Moore, PhD,  Principal Investigator,  Wesleyan University   

Study ID Numbers:  MH66966-01A1
Last Updated:  September 10, 2005
Record first received:  September 7, 2005
ClinicalTrials.gov Identifier:  NCT00158340
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-09-13