The purpose of this study is... To assess whether a behavioral treatment that combines motivational enhancement and cognitive skills training therapy (MET-CBT) is more effective than brief advice in: 1) decreasing use of a full range of psychoactive substances (e.g. marijuana, cocaine, methamphetamines, alcohol, nicotine, opioids) in pregnant substance using and dependent women; 2) decreasing HIV risk behavior; 3) improving birth outcomes (longer gestations and greater birth weight).

Condition	Intervention	Phase
Alcohol Abuse Behavior Therapy Brief Advice Cocaine Abuse Marijuana Abuse	Behavior: Substance-Related Disorders	Phase II

Further study details as provided by National Institute on Drug Abuse (NIDA):

We propose an integrated system of counseling services onsite in primary care obstetrical clinics, comparing a manualized brief advice (closely approximating "treatment as usual") to manualized motivationally enhanced cognitive behavioral therapy. Treatment providers are obstetrical nurses. Therapy patients are taught skill sets designed to enhance motivation to abstain from drugs of abuse, as well as designed to prevent relapse during the perinatal period. It is our hypothesis that therapy patients will be more successful at achieving stated study aims than those receiving brief advice.

Ages Eligible for Study:  16 Years   -   45 Years,  Genders Eligible for Study:  Female

Criteria

Inclusion Criteria:

Pregnant women, age 16 or older, diagnosed with alcohol or drug abuse or dependence, report current or recent use -

Exclusion Criteria:

Nonfluent in English or Spanish, pending incarceration, psychotic, cognitively unable to give informed consent, actively suicidal or homocidal, already engaged in addictions treatment, primarily addicted to nicotine or heroin.

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Please refer to this study by ClinicalTrials.gov identifier  NCT00227903

Connecticut
      Bridgeport Hospital, Bridgeport,  Connecticut,  06106,  United States
      Yale-New Haven Hospital, New Haven,  Connecticut,  06510,  United States

Study chairs or principal investigators

Kimberly A Yonkers, M.D.,  Principal Investigator,  Yale University   

Study ID Numbers:  NIDA-19135-1; R01-19135-1
Last Updated:  December 8, 2005
Record first received:  September 27, 2005
ClinicalTrials.gov Identifier:  NCT00227903
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2006-01-10