Antifungal Drug Helps Kids with Immune Disorder Avoid Hospitalization
... The antifungal medication itraconazole is well tolerated and effectively prevents fungal infections in children who have chronic granulomatous disease (CGD), report scientists from the National Instit...

Primary Immune Deficiency
... What is Primary Immune Deficiency? Selective IgA Deficiency Common Variable Immunodeficiency (CVI) X-Linked Agammaglobulinemia (XLA) Severe Combined Immunodeficiency (SCID) Chronic Granulomatous Disea...

NIAID Initiative Addresses Primary Immune Deficiency Diseases
... The study of primary immunodeficiency diseases — disorders caused by inherited flaws in the immune system that increase susceptibility to infections — has been bolstered by a $12.8 mill...

X-linked severe combined immunodeficiency
... X-linked severe combined immunodeficiency (SCID) is an inherited disorder of the immune system that occurs almost exclusively in males. Boys with X-linked SCID are prone to recurrent and persistent in...

Genes and Disease: DiGeorge syndrome
... DiGeorge syndrome is a rare congenital (i.e. present at birth) disease whose symptoms vary greatly between individuals but commonly include a history of recurrent infection, heart defects, and charact...

Genes and Disease: Diseases of the Immune System
... The immune system is a complex and highly developed system, yet its mission is simple: to seek and kill invaders. If a person is born with a severely defective immune system, death from infection by a...

Genes and Disease: Immunodeficiency with hyper-IgM
... Immunodeficiency with hyper-IgM (HIM) is a rare primary immunodeficiency characterized by the production of normal to increased amounts of IgM antibody of questionable quality and an inability to prod...

Genes and Disease: Severe combined immunodeficiency
... Severe combined immunodeficiency (SCID) represents a group of rare, sometimes fatal, congenital disorders characterized by little or no immune response. The defining feature of SCID, commonly known as...