Cocaine Abuse Clinical Trials

• Pharmacotherapy Dosing Regimen in Cocaine Dependent Individuals - 12
  ClinicalTrials.gov Identifier: NCT00218062 - Recruiting
  Cocaine Abuse; Cocaine-Related Disorders
  
• Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8
  ClinicalTrials.gov Identifier: NCT00218036 - Recruiting
  Cocaine Abuse; Cocaine-Related Disorders
  
• Screening Medications for Cocaine Cessation and Relapse Prevention - 7
  ClinicalTrials.gov Identifier: NCT00218023 - Recruiting
  Cocaine Abuse; Cocaine-Related Disorders
  
• Impulsivity, Brain Function, and Substance Abuse Treatment in Cocaine Dependent Individuals
  ClinicalTrials.gov Identifier: NCT00217997 - Recruiting
  Cocaine Abuse; Cocaine-Related Disorders
  
• Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1
  ClinicalTrials.gov Identifier: NCT00218660 - Active, not recruiting
  Alcoholism; Cocaine Abuse, Cocaine-Related Disorders; Cocaine Dependence
  
• The Maternal Lifestyle Study (MLS)
  ClinicalTrials.gov Identifier: NCT00059540 - Active, not recruiting
  Cocaine Abuse; Cocaine Dependence; Opiate Dependence
  
• Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00218075 - Active, not recruiting
  Cocaine Abuse; Cocaine-Related Disorders
  
• A Double-Blind Placebo-Controlled Trial of Citicoline Add-On Therapy in Patients With a History of Mania or Hypomania and Cocaine Abuse/Dependence
  ClinicalTrials.gov Identifier: NCT00223236 - Active, not recruiting
  Mania/Hypomania; Cocaine Abuse/Dependence
  
• Interactions Between Progesterone and Cocaine in Women. - 1
  ClinicalTrials.gov Identifier: NCT00218257 - Recruiting
  Cocaine Abuse; Cocaine-Related Disorders
  
• Substance Abuse Pre-Treatment Screening Study
  ClinicalTrials.gov Identifier: NCT00439049 - Recruiting
  Cocaine Abuse; Cocaine Dependence; Opiate Dependence; Alcohol Dependence; Substance Abuse
  
• Dopamine Reuptake Inhibitors of Cocaine Abuse - 1
  ClinicalTrials.gov Identifier: NCT00000276 - Active, not recruiting
  Cocaine-Related Disorders
  
• Drug Treatment in Pregnancy - 1
  ClinicalTrials.gov Identifier: NCT00227903 - Not yet recruiting
  Alcohol Abuse; Behavior Therapy; Brief Advice; Cocaine Abuse; Marijuana Abuse
  
• Employment-Based Incentives to Motivate Naltrexone Ingestion and Drug Abstinence in the Treatment of Drug Addiction. - 1
  ClinicalTrials.gov Identifier: NCT00149669 - Not yet recruiting
  Behavior Therapy; Cocaine; Cocaine (IV); Cocaine Abuse; Cocaine Dependence; Contingency management; HIV risk behaviors; Heroin; Heroin Dependence; ...
  
• Treatment of Heroin and Cocaine With Methadone Maintenance and Contingency Management
  ClinicalTrials.gov Identifier: NCT00292110 - Recruiting
  Opiate Dependence; Cocaine Abuse
  
• Effects of Aripiprazole on Cocaine Craving and Self-Administration
  ClinicalTrials.gov Identifier: NCT00373880 - Recruiting
  Cocaine Abuse
  
• Employment-Based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction - 1
  ClinicalTrials.gov Identifier: NCT00249470 - Active, not recruiting
  Cocaine; Cocaine Abuse; Contingency Management; HIV; HIV Risk Behaviors; Heroin; Heroin Dependence; Methadone; Opioid Dependence; Substance Abuse, Intravenous; Alcohol & Drug Use; Sexual Risk Behaviors
  
• Modafinil and Naltrexone for the Treatment of Cocaine and Alcohol Dependence - 3
  ClinicalTrials.gov Identifier: NCT00142818 - Recruiting
  Alcohol-Related Disorders; Alcoholism; Cocaine Abuse, Cocaine-Related Disorders; alcohol & drug use
  
• Disulfiram for Cocaine Abuse
  ClinicalTrials.gov Identifier: NCT00395850 - Recruiting
  Cocaine Dependence
  
• Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals
  ClinicalTrials.gov Identifier: NCT00218049 - Completed
  Cocaine Abuse; Cocaine-Related Disorders
  
• Effect of Clonidine on Imagery Scripts
  ClinicalTrials.gov Identifier: NCT00318760 - Recruiting
  Cocaine Abuse; Heroin Abuse
  
• Employment-Based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2
  ClinicalTrials.gov Identifier: NCT00249457 - Active, not recruiting
  Behavior Therapy; Cocaine Abuse; Cocaine Dependence; Contingency Management; Heroin Dependence; Methadone; Opioid Dependence
  
• Employment-Based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 1
  ClinicalTrials.gov Identifier: NCT00249496 - Recruiting
  Behavior Therapy; Cocaine; Cocaine (IV); Cocaine Abuse; Contingency Management; HIV Risk Behaviors; Heroin; Heroin Dependence; Methadone; Opioid Dependence; Alcohol & Drug Use; Sexual Risk Behaviors
  
• Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1
  ClinicalTrials.gov Identifier: NCT00094315 - Active, not recruiting
  Cocaine-Related Disorders
  
• Development of Human Laboratory Study Model of Cocaine Relapse Prevention. - 1
  ClinicalTrials.gov Identifier: NCT00040066 - Active, not recruiting
  Cocaine-Related Disorders
  
• Methylphenidate Treatment for Cocaine Abuse and ADHD - 1
  ClinicalTrials.gov Identifier: NCT00136734 - Active, not recruiting
  Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders
  
• Atomoxetine for Treating Cocaine Abuse in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
  ClinicalTrials.gov Identifier: NCT00218543 - Active, not recruiting
  Attention Deficit Disorder With Hyperactivity; Cocaine-Related Disorders
  
• Use of Donepezil for Treatment of Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00467389 - Recruiting
  Cocaine Abuse and Dependence
  
• Therapeutic Cocaine Vaccine for Cocaine Dependent Individuals
  ClinicalTrials.gov Identifier: NCT00218088 - Active, not recruiting
  Cocaine-Related Disorders
  
• Effects of Sustained Release d-Amphetamine and Buprenorphine on Drug Seeking Behavior in Opioid and Cocaine Dependent Individuals Who Are Not Seeking Treatment
  ClinicalTrials.gov Identifier: NCT00429767 - Recruiting
  Heroin Dependence; Opioid-Related Disorders; Cocaine Abuse or Dependence
  
• Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00385801 - Active, not recruiting
  Cocaine Dependence
  
• Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1
  ClinicalTrials.gov Identifier: NCT00000315 - Completed
  Cocaine-Related Disorders
  
• Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2
  ClinicalTrials.gov Identifier: NCT00000316 - Completed
  Cocaine-Related Disorders
  
• Assessment of Potential Interactions between Cocaine and RPR 102681 - 1
  ClinicalTrials.gov Identifier: NCT00067535 - Active, not recruiting
  Cocaine-Related Disorders
  
• Disulfiram and Cognitive Behavioral Therapy
  ClinicalTrials.gov Identifier: NCT00350870 - Recruiting
  Cocaine Abuse
  
• Cocaine Effects in Humans: Physiology and Behavior - 1
  ClinicalTrials.gov Identifier: NCT00000200 - Active, not recruiting
  Cocaine-Related Disorders
  
• Computer-Based Training in Cognitive Behavior Therapy
  ClinicalTrials.gov Identifier: NCT00350610 - Recruiting
  Cocaine Abuse
  
• Brain Imaging Studies of the Effects of Cocaine Abstinence
  ClinicalTrials.gov Identifier: NCT00581282 - Recruiting
  Substance Abuse Disorder
  
• Will the Use of Baclofen Reduce Cocaine Use in Patients With Cocaine Dependence?
  ClinicalTrials.gov Identifier: NCT00431938 - Active, not recruiting
  Cocaine Dependence
  
• IV Cocaine Abuse: A Laboratory Model - 1
  ClinicalTrials.gov Identifier: NCT00000212 - Completed
  Cocaine-Related Disorders
  
• IV Cocaine Abuse: A Laboratory Model - 2
  ClinicalTrials.gov Identifier: NCT00000213 - Completed
  Cocaine-Related Disorders
  
• IV Cocaine Abuse: A Laboratory Model - 3
  ClinicalTrials.gov Identifier: NCT00000214 - Completed
  Cocaine-Related Disorders
  
• IV Cocaine Abuse: A Laboratory Model - 4
  ClinicalTrials.gov Identifier: NCT00000215 - Completed
  Cocaine-Related Disorders
  
• Randomised Placebo-Controlled Trial of Modafinil for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00123383 - Active, not recruiting
  Cocaine Dependence
  
• Selegiline Transdermal System for the Treatment of Cocaine Dependence - 1
  ClinicalTrials.gov Identifier: NCT00032929 - Active, not recruiting
  Cocaine-Related Disorders
  
• Effectiveness of Memantine in Treating Cocaine-Dependent Individuals - 2
  ClinicalTrials.gov Identifier: NCT00134901 - Active, not recruiting
  Cocaine-Related Disorders
  
• Venlafaxine to Reduce Cocaine Dependence in Depressed Individuals
  ClinicalTrials.gov Identifier: NCT00249483 - Active, not recruiting
  Cocaine-Related Disorders
  
• Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1
  ClinicalTrials.gov Identifier: NCT00265265 - Active, not recruiting
  Cocaine-Related Disorders
  
• A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction
  ClinicalTrials.gov Identifier: NCT00567814 - Recruiting
  Cocaine Dependence; Cocaine Addiction
  
• Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine - 1
  ClinicalTrials.gov Identifier: NCT00218166 - Active, not recruiting
  Cocaine-Related Disorders
  
• Effectiveness and Costs of Enhanced Cocaine Treatments
  ClinicalTrials.gov Identifier: NCT00167258 - Active, not recruiting
  Cocaine Dependence
  
• Cocaine Abuse and ADHD - 10
  ClinicalTrials.gov Identifier: NCT00000275 - Completed
  Cocaine-Related Disorders
  
• Cocaine Abuse and Attention Deficit Disorder - 3
  ClinicalTrials.gov Identifier: NCT00000268 - Completed
  Cocaine-Related Disorders
  
• Glutaminergic Agents for Cocaine Abuse - 5
  ClinicalTrials.gov Identifier: NCT00000280 - Completed
  Cocaine-Related Disorders
  
• GBR 12909 Study in Cocaine Experienced African American Volunteers - 1
  ClinicalTrials.gov Identifier: NCT00089687 - Active, not recruiting
  Cocaine-Related Disorders
  
• Assessment of Potential Interactions between Cocaine and Tolcapone - 1
  ClinicalTrials.gov Identifier: NCT00033059 - Active, not recruiting
  Cocaine-Related Disorders
  
• Baclofen for the Treatment of Cocaine Dependence - 1
  ClinicalTrials.gov Identifier: NCT00082485 - Active, not recruiting
  Cocaine-Related Disorders
  
• Modafinil for the Treatment of Cocaine Dependence - 1
  ClinicalTrials.gov Identifier: NCT00100100 - Active, not recruiting
  Cocaine-Related Disorders
  
• Propranolol for Treatment of Cocaine Addiction - 2
  ClinicalTrials.gov Identifier: NCT00000197 - Active, not recruiting
  Cocaine-Related Disorders
  
• Tiagabine for the Treatment of Cocaine Dependence - 1
  ClinicalTrials.gov Identifier: NCT00086255 - Active, not recruiting
  Cocaine-Related Disorders
  
• Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions with Cocaine - 1
  ClinicalTrials.gov Identifier: NCT00033046 - Active, not recruiting
  Cocaine-Related Disorders; Drug Administration Schedule; Infusions, Intravenous
  
• Interaction of Stress and Progesterone Levels on Cocaine Cue Induced Craving in Cocaine Dependent Individuals
  ClinicalTrials.gov Identifier: NCT00535002 - Not yet recruiting
  Cocaine Related Disorders
  
• A Free Treatment Study for Cocaine Dependence Looking at the Effectiveness of Mirtazapine in Treating Cocaine Dependent Individuals Who Also Suffer From Depression
  ClinicalTrials.gov Identifier: NCT00249444 - Recruiting
  Cocaine Dependence; Depression
  
• GABA Medications for Cocaine Addiction - 3
  ClinicalTrials.gov Identifier: NCT00142883 - Terminated
  
  
• Effect of Nefazodone on Relapse in Females with Cocaine Abuse - 10
  ClinicalTrials.gov Identifier: NCT00000293 - Completed
  Cocaine-Related Disorders
  
• Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4
  ClinicalTrials.gov Identifier: NCT00000301 - Completed
  Cocaine-Related Disorders
  
• Rapid Evaluation of Baclofen for Treatment of Cocaine Abuse/Dependence - 6
  ClinicalTrials.gov Identifier: NCT00000303 - Completed
  Cocaine-Related Disorders
  
• Drug Interaction Study with NS2359 and Cocaine in Cocaine Experienced Volunteers - 1
  ClinicalTrials.gov Identifier: NCT00032916 - Active, not recruiting
  Cocaine-Related Disorders; Drug Administration Schedule; Infusions, Intravenous
  
• Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse
  ClinicalTrials.gov Identifier: NCT00292123 - Completed
  Opioid Dependence; Cocaine Abuse
  
• Free Treatment for Cocaine Dependence: A Placebo-Controlled Study of Mixed Amphetamine Salts (Adderall-XR) and Topiramate for the Treatment of Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00421603 - Recruiting
  Cocaine Dependence
  
• Assessment of Potential Interactions Between GBR 12909 and Cocaine - 1
  ClinicalTrials.gov Identifier: NCT00100113 - Active, not recruiting
  Cocaine-Related Disorders
  
• Assessment of the Potential Interactions between Cocaine and GBR 12909 - 1
  ClinicalTrials.gov Identifier: NCT00051896 - Active, not recruiting
  Cocaine-Related Disorders
  
• Methylphenidate in the Treatment of Cocaine Dependent Patients with Adult Attention Deficit Hyperactivity Disorder - 5
  ClinicalTrials.gov Identifier: NCT00015223 - Active, not recruiting
  Cocaine-Related Disorders; Substance-Related Disorders
  
• Medication Development for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00223626 - Recruiting
  Cocaine Dependence
  
• Cocaine Vaccine for Methadone Maintained Patients. - 1
  ClinicalTrials.gov Identifier: NCT00142857 - Active, not recruiting
  Cocaine; Study is not suspended. Enrollment started two years ago and completed enrollment in July 2005
  
• Double Blind Study of Vigabatrin for the Treatment of Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00527683 - Active, not recruiting
  Cocaine Dependence
  
• Tryptophan and Behavior Therapy for Cocaine Abuse - 1
  ClinicalTrials.gov Identifier: NCT00000324 - Completed
  Cocaine-Related Disorders
  
• Interaction between Cocaine and Quetiapine - 1
  ClinicalTrials.gov Identifier: NCT00087750 - Active, not recruiting
  Cocaine-Related Disorders
  
• Effectiveness of Topiramate in Treating Cocaine Dependent Individuals - 1
  ClinicalTrials.gov Identifier: NCT00249691 - Recruiting
  Cocaine-Related Disorders
  
• Efficacy of Mirtazapine in Depressed Cocaine Dependent Subjects
  ClinicalTrials.gov Identifier: NCT00322309 - Recruiting
  Cocaine Dependence; Depression
  
• Acoustic Startle Reduction In Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00430690 - Recruiting
  Cocaine-Related Disorders
  
• Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1
  ClinicalTrials.gov Identifier: NCT00218387 - Recruiting
  Cocaine Dependence
  
• Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients
  ClinicalTrials.gov Identifier: NCT00495092 - Recruiting
  Cocaine Related Disorders
  
• Efficacy of Varenicline in Methadone-Stabilized Cocaine Users
  ClinicalTrials.gov Identifier: NCT00567320 - Recruiting
  An Effective Pharmacotherapy for Cocaine Use Disorders
  
• Cocaine-Metyrapone Interaction Study - 1
  ClinicalTrials.gov Identifier: NCT00033098 - Active, not recruiting
  Cocaine-Related Disorders; Infusions, Intravenous
  
• Ondansetron for the Treatment of Cocaine Dependence - 1
  ClinicalTrials.gov Identifier: NCT00033085 - Active, not recruiting
  Cocaine-Related Disorders; Drug Administration Schedule
  
• Study to Improve Scientific Understanding of the Cardiovascular Actions of Cocaine
  ClinicalTrials.gov Identifier: NCT00338546 - Recruiting
  Cocaine Induced Sympathoexciation and Vasoconstriction
  
• Efficacy of Levetiracetam in Cocaine-Abusing Methadone Maintained Patients
  ClinicalTrials.gov Identifier: NCT00577005 - Recruiting
  Cocaine Dependence; Opioid Dependency
  
• A Transtheoretical Model Group Therapy for Cocaine
  ClinicalTrials.gov Identifier: NCT00178776 - Recruiting
  Cocaine Use Disorders
  
• Prazosin for ETOH or Cocaine Craving
  ClinicalTrials.gov Identifier: NCT00240227 - Recruiting
  Cocaine Dependence; Alcoholism
  
• Cocaine Withdrawal and Pharmacotherapy Response
  ClinicalTrials.gov Identifier: NCT00566969 - Recruiting
  Cocaine-Related Disorders
  
• Effectiveness of Disulfiram and Naltrexone Used in Combination to Treat Individuals Diagnosed with Both Cocaine and Alcohol Dependence - 1
  ClinicalTrials.gov Identifier: NCT00142844 - Active, not recruiting
  Alcohol-Related Disorders; Alcoholism; Cocaine-Related Disorders
  
• Treatment of Cocaine Dependence: Comparison of Three Doses of Dextro-Amphetamine Sulfate and Placebo
  ClinicalTrials.gov Identifier: NCT00218348 - Recruiting
  Cocaine-Related Disorders
  
• Effects of Vigabatrin on Cocaine Self-Administration
  ClinicalTrials.gov Identifier: NCT00373581 - Recruiting
  Cocaine Dependence
  
• Modafinil Treatment for Cocaine-Dependent Individuals - 1
  ClinicalTrials.gov Identifier: NCT00129285 - Recruiting
  Cocaine-Related Disorders
  
• Nefazodone in the Treatment of Cocaine Dependence and Depression - 4
  ClinicalTrials.gov Identifier: NCT00015210 - Active, not recruiting
  Cocaine-Related Disorders; Substance-Related Disorders
  
• A study of Cabergoline for the Treatment of Cocaine Dependence - 1
  ClinicalTrials.gov Identifier: NCT00033111 - Active, not recruiting
  Cocaine-Related Disorders; Substance-Related Disorders
  
• Treatment of Alcoholism with Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00136162 - Active, not recruiting
  Alcoholism; Alcohol-Related Disorders; Cocaine-Related Disorders
  
• Propranolol and Amantadine for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00128349 - Active, not recruiting
  Cocaine Dependence
  
• A Controlled Trial: Subjects Enrolled in the Study Receive Either NAC or Placebo. NAC is a N Acetyl Pro-Drug of the Naturally-Occurring Amino Acid Cystine. Subjects Enrolled in the Study Are Addicted to Cocaine - 1
  ClinicalTrials.gov Identifier: NCT00218491 - Recruiting
  Cocaine Dependence
  
• Early Phase II Trials for Cocaine Medication Development - 1
  ClinicalTrials.gov Identifier: NCT00000317 - Active, not recruiting
  Cocaine-Related Disorders; Substance-Related Disorders