Drug and Medical Device Safety Clinical Trials

• Improving Pediatric Safety and Quality with Health Care Information Technology
  ClinicalTrials.gov Identifier: NCT00134823 - Active, not recruiting
  MEDICATION ERRORS; MEDICAL RECORDS SYSTEMS, COMPUTERIZED; PATIENT SAFETY; QUALITY IMPROVEMENT
  
• Safety and Effectiveness Study of the Ensure Medical Vascular Closure Device
  ClinicalTrials.gov Identifier: NCT00345631 - Active, not recruiting
  Angioplasty, Transluminal, Percutaneous Coronary; Coronary Arteriosclerosis
  
• Safety and Feasibility of Endovascular Cooling Device in Patients with Hypothermic Cardiopulmonary Resuscitation
  ClinicalTrials.gov Identifier: NCT00154674 - Recruiting
  Cardiac Arrest
  
• Serious Medication Errors in Pediatrics: Evaluation of Prevention Strategies
  ClinicalTrials.gov Identifier: NCT00153205 - Recruiting
  medication errors; medical records systems, computerized; patient safety
  
• A Two Year Safety and Efficacy Study in Obese Patients
  ClinicalTrials.gov Identifier: NCT00131404 - Active, not recruiting
  Obesity and obesity-related medical conditions
  
• Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia
  ClinicalTrials.gov Identifier: NCT00067613 - Active, not recruiting
  Bronchopulmonary Dysplasia
  
• A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device (DGE) and an FDA Approved Device for the Correction of Nasolabial Folds (NLFs)
  ClinicalTrials.gov Identifier: NCT00444626 - Active, not recruiting
  Facial Wrinkles at the Nasolabial Folds
  
• An Eighteen Month Efficacy and Safety Study in Obese Patients
  ClinicalTrials.gov Identifier: NCT00131430 - Active, not recruiting
  Obesity and obesity-related medical conditions
  
• Montreal Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device
  ClinicalTrials.gov Identifier: NCT00571610 - Enrolling by invitation
  Heart Failure; Mitral Regurgitation
  
• Prostate Immobilization Device used during Radiation Treatments to Decrease Rectal Bleeding
  ClinicalTrials.gov Identifier: NCT00114985 - Active, not recruiting
  Prostate Cancer
  
• REPLACE: Implantable Cardiac Pulse Generator Replacement Registry
  ClinicalTrials.gov Identifier: NCT00395447 - Recruiting
  Device Replacement; Elective Replacement (ERI); Device Advisory; Device Upgrade; Postoperative Complications
  
• Drug Facts Page or a Short Drug Summary in Helping Patients and Doctors Understand Medical Information
  ClinicalTrials.gov Identifier: NCT00450931 - Active, not recruiting
  Health Status Unknown
  
• Safety and Efficacy of the BrainPort™ Balance Device to Improve Balance in Bilateral Vestibular Hypofunction
  ClinicalTrials.gov Identifier: NCT00254228 - Active, not recruiting
  Vestibular Disease
  
• A Study to Assess the Safety and Efficacy of a Microneedle Device for Local Anesthesia
  ClinicalTrials.gov Identifier: NCT00539084 - Active, not recruiting
  Local Anesthesia; Intradermal Injections
  
• Evaluation of the Zilver PTX Drug-Eluting Stent in the Above-the-Knee Femoropopliteal Artery
  ClinicalTrials.gov Identifier: NCT00120406 - Recruiting
  Peripheral Vascular Diseases
  
• Efficacy and Safety of DBS of the GPi in Patients with Primary Generalized and Segmental Dystonia
  ClinicalTrials.gov Identifier: NCT00142259 - Active, not recruiting
  Dystonia
  
• Aachen Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device to Reduce Mitral Regurgitation
  ClinicalTrials.gov Identifier: NCT00572091 - Enrolling by invitation
  Heart Failure; Mitral Regurgitation
  
• Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device to Reduce Mitral Regurgitation
  ClinicalTrials.gov Identifier: NCT00568230 - Enrolling by invitation
  Heart Failure; Mitral Regurgitation
  
• HAART Adherence Interventions
  ClinicalTrials.gov Identifier: NCT00273780 - Active, not recruiting
  Patient Compliance
  
• Clinical Study to Determine Safety and Effectiveness of KEEPASLEEP Device in Simple Snorers.
  ClinicalTrials.gov Identifier: NCT00211627 - Recruiting
  Snoring; Sleep Apnea Syndromes
  
• The SUNRISE Registry - Safety and Performance of the CORDIS ENTERPRISE™ Vascular Reconstruction Device and Delivery System
  ClinicalTrials.gov Identifier: NCT00486226 - Recruiting
  Intracranial Aneurysm
  
• Safety and Efficacy of the ZoMaxx(TM) Drug-Eluting Stent System in Coronary Arteries
  ClinicalTrials.gov Identifier: NCT00140101 - Recruiting
  Coronary Disease; Coronary Atherosclerosis; Arterial Occlusive Diseases
  
• ResQ Trial: Impact of an Impedance Threshold Device and Active Compression Decompression CPR on Survival from Out-of-Hospital Cardiac Arrest
  ClinicalTrials.gov Identifier: NCT00189423 - Recruiting
  Heart Arrest; Death, Sudden, Cardiac; Cardiopulmonary Resuscitation
  
• Safety and Efficacy of the CryoCor™ Cardiac Cryoablation System for the Treatment of Atrial Flutter
  ClinicalTrials.gov Identifier: NCT00113178 - Active, not recruiting
  Atrial Flutter
  
• Below Study - Balloonangioplasty or Stents with ReoPro for Prevention of Subacute Reocclusion in Arteries Below the Knee
  ClinicalTrials.gov Identifier: NCT00163254 - Active, not recruiting
  Patients above 18 years
  
• Wallis Mechanical Normalization System for Low Back Pain
  ClinicalTrials.gov Identifier: NCT00134537 - Active, not recruiting
  Degenerative Disc Disease of the lumbar spine
  
• Prosthetic Limbs After Leg Amputation: Alternative Method of Socket Design
  ClinicalTrials.gov Identifier: NCT00061217 - Active, not recruiting
  Amputation
  
• Clinical Assessment of an in-Patient Glucose Monitoring System (Accu-Chek Inform Cobas IT 1000)
  ClinicalTrials.gov Identifier: NCT00486681 - Recruiting
  Diabetes Mellitus; Blood Glucose; Hospital Information Systems; Medical Device
  
• Safety and Efficacy of a Heparin-Coated Intraocular Lens in Uveitis
  ClinicalTrials.gov Identifier: NCT00000119 - Active, not recruiting
  Cataract; Uveitis
  
• Study to Evaluate the Safety and Efficacy of a Low Level Light Device in Patients With Knee Osteoarthritis
  ClinicalTrials.gov Identifier: NCT00375544 - Recruiting
  Osteoarthritis, Knee
  
• CESA 5.10 Investigation to Compare the Efficacy and Safety of the Adacolumn® Apheresis Device in Patients With Active Ulcerative Colitis
  ClinicalTrials.gov Identifier: NCT00366925 - Recruiting
  Ulcerative Colitis
  
• Influence of Assistive Device Use While Performing Dual Task in Patients with Stroke
  ClinicalTrials.gov Identifier: NCT00173719 - Recruiting
  Stroke
  
• Safety and Efficacy of an Ambulatory Biofeedback Device for Primary Insomnia
  ClinicalTrials.gov Identifier: NCT00415714 - Recruiting
  Primary Insomnia
  
• Medical Office Intervention for Adolescent Drug Use - 1
  ClinicalTrials.gov Identifier: NCT00229983 - Recruiting
  Alcohol Abuse, Alcohol-Related Disorders; Drug Counseling; Substance-Related Disorders; Alcohol & Drug Use
  
• X-Change HF - Exchange of the Existing Pacemaker / ICD in Bradicardia Patients Suffering from Heart Failure
  ClinicalTrials.gov Identifier: NCT00157846 - Recruiting
  Bradycardia; Heart Failure; LVEF < 35%
  
• Investigating the Safety of srTMS in the Treatment of Parkinson's Disease
  ClinicalTrials.gov Identifier: NCT00063284 - Recruiting
  Parkinson Disease
  
• Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT)
  ClinicalTrials.gov Identifier: NCT00000143 - Active, not recruiting
  Cytomegalovirus Retinitis; HIV Infections
  
• Evaluation of the Safety and Effectiveness of the OPTIMIZER System in Subjects with Heart Failure: FIX-HF-5
  ClinicalTrials.gov Identifier: NCT00112125 - Active, not recruiting
  Heart Failure, Congestive
  
• Safety Study of Specific Tumor Target Drug Plus Immune System Therapy in Patients With Kidney Cancer
  ClinicalTrials.gov Identifier: NCT00440973 - Active, not recruiting
  Carcinoma, Renal Cell
  
• Endobronchial Valve for Emphysema PalliatioN Trial (VENT) Cost-Effectiveness Sub-Study
  ClinicalTrials.gov Identifier: NCT00137956 - Active, not recruiting
  Emphysema; Chronic Obstructive Pulmonary Disease
  
• To Study And Compare Bioavailability And Safety Of Four Different Formulations Of The Study Drug
  ClinicalTrials.gov Identifier: NCT00436228 - Active, not recruiting
  Healthy
  
• Safety and Efficacy of NeuroFlo Technology in Ischemic Stroke (SENTIS)
  ClinicalTrials.gov Identifier: NCT00119717 - Recruiting
  Cerebrovascular Accident
  
• A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis
  ClinicalTrials.gov Identifier: NCT00296569 - Active, not recruiting
  Osteoarthritis
  
• Safety and Efficacy of Using NaviAid™ BGE Device (Balloon Guided Endoscopy) For Endoscopic Diagnosis and Treatment
  ClinicalTrials.gov Identifier: NCT00398203 - Not yet recruiting
  Intestinal Diseases
  
• Change and Clinical Significance of Plantar Fascia Thickness After ESWT
  ClinicalTrials.gov Identifier: NCT00155324 - Recruiting
  Plantar Fasciitis
  
• Safety of a Influenza Vaccine Produced Either in Mammalian Cell Culture or in Embryonated Hen Eggs in Adults and Elderly With and Without Underlying Medical Conditions, and Immunogenicity in a Subset of Subjects With Underlying Medical Conditions
  ClinicalTrials.gov Identifier: NCT00560066 - Recruiting
  Seasonal Influenza; Vaccine
  
• A Safety Study of Hylan GF-20 to Treat Shoulder Osteoarthritis
  ClinicalTrials.gov Identifier: NCT00253799 - Active, not recruiting
  Painful Shoulder Osteoarthritis
  
• Clinical Investigation of the Medtronic Concerto™ Device
  ClinicalTrials.gov Identifier: NCT00268320 - Active, not recruiting
  Congestive Heart Failure, Atrial Arrhythmia, Atrial Tachyarrhythmia, Atrial Fibrillation
  
• Emergency Pharmacist Safety Study
  ClinicalTrials.gov Identifier: NCT00382434 - Recruiting
  Adverse Drug Event, Potential Adverse Drug Event, and Quality Measures
  
• Safety and Tolerability Study of Drug to Treat Schizophrenia
  ClinicalTrials.gov Identifier: NCT00044005 - Active, not recruiting
  Schizophrenia
  
• Non-Polymer-Based, Rapamycin-Eluting Stents to Prevent Restenosis
  ClinicalTrials.gov Identifier: NCT00152308 - Recruiting
  Coronary Disease
  
• Safety and Efficacy Study of a New Device for Tattoo Removal
  ClinicalTrials.gov Identifier: NCT00409162 - Not yet recruiting
  Tattoo; Healthy
  
• 3-D Laser Imaging to Analyze Neck Movement
  ClinicalTrials.gov Identifier: NCT00022828 - Active, not recruiting
  Neck Pain; Manipulation, Spinal
  
• Evaluation of the Safety and Efficacy of Using ImplantLock Device - Dental Implant Accessory
  ClinicalTrials.gov Identifier: NCT00519571 - Not yet recruiting
  Dental Implantation
  
• Efficacy and Safety of an Oral Growth Hormone Drug in the Treatment of Fibromyalgia
  ClinicalTrials.gov Identifier: NCT00116129 - Active, not recruiting
  Fibromyalgia
  
• Microvascular Response in Diabetes Mellitus
  ClinicalTrials.gov Identifier: NCT00160927 - Recruiting
  Diabetes Mellitus
  
• Adjustable Continence Therapy (ACT) Device for the Treatment of Female Stress Urinary Incontinence
  ClinicalTrials.gov Identifier: NCT00113555 - Active, not recruiting
  Urinary Incontinence
  
• AutoVPAP Versus VPAP; Assessment of Sleep and Ventilation
  ClinicalTrials.gov Identifier: NCT00252252 - Active, not recruiting
  Chest Wall Disorder; Neuromuscular Disease
  
• A Repeated-Dose Evaluation of a Pain Relieving Drug Use and Safety of OROS Hydromorphone HCI in Patients With Chronic Non-Malignant Pain
  ClinicalTrials.gov Identifier: NCT00410644 - Active, not recruiting
  Opioid; Analgesics; Pain
  
• A Repeated-Dose Evaluation of Use of a Pain Relieving Drug and Safety of OROS Hydromorphone HCI in Patients With Chronic Cancer Pain
  ClinicalTrials.gov Identifier: NCT00411034 - Active, not recruiting
  Analgesics, Opioid; Pain
  
• Functional Electrical Stimulation for Footdrop in Hemiparesis
  ClinicalTrials.gov Identifier: NCT00148343 - Recruiting
  Stroke; Hemiplegia
  
• A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Dental Pain
  ClinicalTrials.gov Identifier: NCT00387140 - Active, not recruiting
  Pain, Postoperative; Tooth Extraction
  
• Prospective and Randomized Study to Evaluate Interest of Ultracision Use in Inguinal Lymph Nodes Curage.
  ClinicalTrials.gov Identifier: NCT00224744 - Recruiting
  Vulvar Neoplasms; Skin Neoplasms
  
• Safety, Efficacy and Psychological Effects of Treating Antiretroviral Drug-Induced Facial Lipoatrophy With Bio-Alcamid
  ClinicalTrials.gov Identifier: NCT00333684 - Active, not recruiting
  Human Immunodeficiency Virus; Facial Lipoatrophy
  
• Study of a Repetitive Transcranial Magnetic Stimulation (rTMS) Device for the Treatment of Major Depressive Disorder
  ClinicalTrials.gov Identifier: NCT00104611 - Active, not recruiting
  Major Depressive Disorder
  
• Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers
  ClinicalTrials.gov Identifier: NCT00152724 - Recruiting
  Healthy volunteers
  
• A Study of the Effectiveness of Near Infrared Light for the Treatment of Painful Peripheral Neuropathy
  ClinicalTrials.gov Identifier: NCT00125268 - Recruiting
  Peripheral Neuropathy
  
• Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke
  ClinicalTrials.gov Identifier: NCT00142792 - Recruiting
  Stroke, Acute; Stroke; Hemiparesis
  
• SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries
  ClinicalTrials.gov Identifier: NCT00114972 - Active, not recruiting
  Coronary Artery Disease
  
• Efficacy and Safety of Low-Molecular Weight Heparin for Thromboprophylaxis in Acutely Ill Medical Patients
  ClinicalTrials.gov Identifier: NCT00311753 - Recruiting
  Embolism
  
• Cystic Fibrosis and Totally Implantable Vascular Access Devices: Evaluation of the Incidence of Venous Thrombosis Related to the Catheter and Study of the Genetic and Acquired Risk Factors
  ClinicalTrials.gov Identifier: NCT00244270 - Not yet recruiting
  Cystic Fibrosis; Totaly Implantable Vascular Access Device
  
• Mirroring a Movement
  ClinicalTrials.gov Identifier: NCT00123448 - Active, not recruiting
  
  
• DECIPHER STICH - Ancillary to STICH
  ClinicalTrials.gov Identifier: NCT00074724 - Active, not recruiting
  Cardiovascular Diseases; Coronary Disease; Heart Failure; Heart Failure, Congestive; Heart Diseases
  
• A Safety Study to Evaluate 12 Weeks of Treatment with Clevudine in Patients Infected with Hepatitis B Virus.
  ClinicalTrials.gov Identifier: NCT00044135 - Active, not recruiting
  Hepatitis B
  
• A Safety Study of EPC2407, A Anti-Cancer Drug With Vascular Disrupting Activity: In Patients With Advanced Cancer
  ClinicalTrials.gov Identifier: NCT00423410 - Active, not recruiting
  Advanced Cancer
  
• Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice Daily
  ClinicalTrials.gov Identifier: NCT00002241 - Active, not recruiting
  HIV Infections
  
• Treatment for Migraines With an Implantable Device
  ClinicalTrials.gov Identifier: NCT00286078 - Active, not recruiting
  Migraine
  
• Safety and Effectiveness of a Three-Drug Combination Treatment for Recently Infected or Converted HIV Patients
  ClinicalTrials.gov Identifier: NCT00007202 - Active, not recruiting
  HIV Infections
  
• Efficacy and Safety of an Investigational Drug for Insomnia in Adults
  ClinicalTrials.gov Identifier: NCT00095069 - Active, not recruiting
  Insomnia
  
• Novofine Autocover Safety Needle Versus BD Safety Glide
  ClinicalTrials.gov Identifier: NCT00121355 - Completed
  Health Personnel
  
• Improving Geriatric Drug Safety in Underserved Practices
  ClinicalTrials.gov Identifier: NCT00277173 - Recruiting
  Cardiovascular Diseases
  
• Using Telephone Technology to Prevent Relapse After Alcoholism Treatment
  ClinicalTrials.gov Identifier: NCT00132795 - Recruiting
  Alcoholism
  
• Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIV
  ClinicalTrials.gov Identifier: NCT00027339 - Active, not recruiting
  HIV Infections
  
• Restoration of Walking in Multiple Sclerosis Using Treadmill Training.
  ClinicalTrials.gov Identifier: NCT00156676 - Recruiting
  Multiple Sclerosis
  
• Evaluate the Efficacy and Safety of Photodynamic Therapy in the Treatment of Malignant Intracranial Tumors
  ClinicalTrials.gov Identifier: NCT00243490 - Not yet recruiting
  Malignant Intracranial Tumors; Glioblastoma Multiforme; Anaplastic Astrocytomas; Anaplastic Oligodendrogliomas; Anaplastic Ependymoma
  
• Safety Study of Ophthalmic Solution in Healthy, Normal Volunteers
  ClinicalTrials.gov Identifier: NCT00223951 - Active, not recruiting
  Healthy Volunteers Eligible for Study; Drug Being Developed for Allergic Conjunctivitis
  
• Intra-Individual Comparison of Sirolimus and Paclitaxel Coated Stent (FRE-RACE Study)
  ClinicalTrials.gov Identifier: NCT00130546 - Recruiting
  Coronary Artery Disease
  
• Safety and Efficacy Study of the Investigational Drug Pagoclone, in the Treatment of Persistent Developmental Stuttering (PDS)
  ClinicalTrials.gov Identifier: NCT00239915 - Active, not recruiting
  Persistent Developmental Stuttering
  
• Measurement of Digital Colposcopy for Fluorescence Spectroscopy of TNC Using a Second Device
  ClinicalTrials.gov Identifier: NCT00503919 - Active, not recruiting
  Cervix
  
• Evaluation of the H-Coil Transcranial Magnetic Stimulation(TMS) Device- Augmentation for Drug Resistant Depression
  ClinicalTrials.gov Identifier: NCT00577070 - Not yet recruiting
  Major Depression
  
• Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients
  ClinicalTrials.gov Identifier: NCT00050895 - Active, not recruiting
  HIV Infections
  
• Efficacy and Safety In Poorly Controlled Type 2 Diabetics
  ClinicalTrials.gov Identifier: NCT00044460 - Active, not recruiting
  type 2 diabetes
  
• Phase 2 Evaluation of the ELAD System in the Management of Acute Liver Failure
  ClinicalTrials.gov Identifier: NCT00030225 - Recruiting
  Fulminant Hepatic Failure
  
• A Study to Assess the Efficacy, Safety, and Tolerability of a Novel Investigational Drug in Rheumatoid Arthritis Patients
  ClinicalTrials.gov Identifier: NCT00132769 - Active, not recruiting
  Rheumatoid Arthritis
  
• Brief Intervention for Prescription Drug Misuse in General Hospital
  ClinicalTrials.gov Identifier: NCT00514839 - Active, not recruiting
  Abuse of Prescription Drug; Dependence on Prescription Drugs; Regular Consumption of Prescription Drug
  
• Medication Errors and Adverse Drug Events (ADEs) in Ambulatory Pediatrics
  ClinicalTrials.gov Identifier: NCT00229671 - Recruiting
  Pediatric Patients With a Variety of Medical Conditions.
  
• Study to Evaluate the Performance and Safety of Expedial and Compare It to ePTFE Vascular Access Grafts.
  ClinicalTrials.gov Identifier: NCT00131872 - Recruiting
  End Stage Renal Disease
  
• Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD)
  ClinicalTrials.gov Identifier: NCT00006517 - Completed
  Seasonal Affective Disorder; Mood Disorders; Depressive Disorders
  
• Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment
  ClinicalTrials.gov Identifier: NCT00450216 - Recruiting
  Ulcer
  
• Safety of AMD11070, a New Anti-HIV Drug, in HIV Uninfected Men
  ClinicalTrials.gov Identifier: NCT00063804 - Active, not recruiting
  HIV Infections