GoldBamboo.com - Knowledge is strong medicine
  

Pegaptanib Sodium (Macugen) Compared to Sham Injection in Patients with Diabetic Macular Edema (DME) Involving the Center of the Macula - Article


  Not Signed In - Sign In / Register




General Topics A-Z

Edema

Water Retention

Clinical Trial: Pegaptanib Sodium (Macugen) Compared to Sham Injection in Patients with Diabetic Macular Edema (DME) Involving the Center of the Macula

This study is currently recruiting patients.
Verified by Eyetech Pharmaceuticals September 2005

Sponsors and Collaborators: Eyetech Pharmaceuticals
Pfizer
Information provided by: Eyetech Pharmaceuticals
ClinicalTrials.gov Identifier: NCT00148811

Purpose

The purpose of the study to determine if pegaptanib sodium (Macugen) is safe and effective in slowing down the leakage of fluid within the eye and thereby stabilizing or improving vision when compared to placebo injections.
Condition Intervention Phase
Diabetic Macular Edema
  Drug: pegaptanib sodium (Macugen)
 Phase II
Phase III

MedlinePlus related topics:  Diabetic Eye Problems;   Edema;   Vision Impairment and Blindness

Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study

Official Title: A Phase 2/3 Randomized, Controlled, Double-Masked, Multi-Center, Comparative Dose-Finding Trial, in Parallel Groups, to Compare the Safety and Efficacy of Intravitreous Injections of 0.3, 0.03 or 0.003 Mg Pegaptanib Sodium (Macugen), Given as Often as Every 6 Weeks for 3 Years, to Sham Injections in Subjects with Diabetic Macular Edema (DME) Involving the Center of the Macula.

Further Study Details: 

Expected Total Enrollment:  900

Study start: September 2005;  Expected completion: February 2010

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • Diabetic macular edema with corresponding leakage on fluorescein angiogram
  • Foveal thickness of at least 300 microns on OCT.
  • Best corrected visual acuity in the study eye between 20/50 and 20/200
  • Women of childbearing potential must use two effective forms of contraception throughout the duration of the study

Exclusion Criteria:

  • Prior or current need for panretinal photocoagulation
  • Prior treatment with an investigational agent for DME

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00148811

Macugen Information      1-866-622-8436 

Texas
      Valley Retina Associates, McAllen,  Texas,  785003,  United States; Recruiting
Macugen Information  866-622-8436 

More Information

Study ID Numbers:  EOP1013
Last Updated:  September 7, 2005
Record first received:  September 6, 2005
ClinicalTrials.gov Identifier:  NCT00148811
Health Authority: United States: Food and Drug Administration
ClinicalTrials.gov processed this record on 2005-09-13


Source: ClinicalTrials.gov
Cache Date: September 14, 2005


Take control over your directory listings...INSTANTLY

Every day, thousands of users find businesses like yours in the GoldBamboo directory.

Limited Time Offer!!!

For only $50 a year, a savings of 50% off our standard rate:

  • Edit your listing (whenever you want!)
  • Link to your website
  • Choose which categories you are listed in
  • Describe your services

The process will take only a few minutes and consists of 3 easy steps:

1. Register     >     2. Edit Listings     >     3. Publish

Your Company
your street
yourtown, YS 12345
888-888-8888



No Thanks

Popular Treatments

Acne Treatment ADHD Treatment Allergy Treatment Alzheimer's Treatment
Anemia Treatment Arthritis Treatment Asthma Treatment Bipolar Disorder Treatment
Bird Flu Treatment Bladder Cancer Treatment Bladder Control Treatment Blood Pressure Treatment
Brain Tumor Treatment Breast Cancer Treatment Bronchitis Treatment Cancer Treatment
Cancer Alternative Treatment Cataract Treatment Cirrhosis Treatment Colitis Treatment
Colon Cancer Treatment Common Cold Treatment Conjunctivitis Treatment Constipation Treatment
Crohn's Disease Treatment Cystic Fibrosis Treatment Depression Treatment Dermatitis Treatment
Diabetes Treatment Edema Treatment Epilepsy Treatment Erectile Dysfunction Treatment
Fibromyalgia Treatment GERD Treatment Glaucoma Treatment Gout Treatment
Hay Fever Treatment Headache Treatment Heart Disease Treatment Hepatitis Treatment
High Blood Pressure Treatment High Cholesterol Treatment Hives Treatment Hypertension Treatment
Hypoglycemia Treatment IBS Treatment Impotence Treatment Indigestion Treatment
Infertility Treatment Influenza Treatment Insomnia Treatment Lactose Intolerance Treatment
Leukemia Treatment Lung Cancer Treatment Lyme Disease Treatment Macular Degeneration Treatment
Menopause Treatment Migraine Treatment Osteoarthritis Treatment Osteoporosis Treatment
Pancreatic Cancer Treatment PMS Treatment Pneumonia Treatment Prostate Diseases Treatment
Restless Leg Treatment Rheumatoid Arthritis Treatment Sepsis Treatment Sinusitis Treatment
Skin Cancer Treatment Sleep Apnea Treatment Snoring Treatment Stroke Treatment
Testicular Cancer Treatment
GoldBambooTM

Your Integrative Health and Wellness Resource for Edema.

July 26, 2008


Page Updated: May 11, 2006
Disclaimer: All material displayed on the GoldBamboo.com website is provided for educational purposes only. Consult a physician regarding the applicability of any information found on GoldBamboo.com to your symptoms or medical condition.

Insurance Quotes | Home | About Us | Link To Us | Feedback | Disclaimer | Privacy Policy | Terms of Use | Google Co-op | Health Forums

Copyright © 2004-2008 - Gold Bamboo LLC
All rights reserved.

HONcode accreditation seal.

We comply with the HONcode standard for health trust worthy information:
verify here.