The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on risk for type 2 diabetes, fatness, fitness, blood cholesterol levels, and other cardiovascular risk factors in overweight elementary schoolchildren. The hypothesis is that the more exercise a child does, the more benefit he or she will gain in reducing the risk of diabetes and other cardiovascular diseases.

Condition	Treatment or Intervention	Phase
Obesity	Behavior: Aerobic exercise program	Phase II

Further Study Details: 

Primary Outcomes: Insulin area under the curve (oral glucose tolerance test); Body composition (% body fat, visceral fat); Aerobic fitness
Secondary Outcomes: Glucose (oral glucose tolerance test); Lipid profile; Inflammation (C-reactive protein, fibrinogen); Blood pressure
Expected Total Enrollment:  240

The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on insulin response to the oral glucose tolerance test, body composition, fitness, lipid profile, inflammation and other metabolic syndrome components in overweight elementary schoolchildren.

Ages Eligible for Study:  7 Years   -   11 Years,  Genders Eligible for Study:  Both

Accepts Healthy Volunteers

Criteria

Inclusion Criteria:

• Overweight, sedentary children
• Black or white race
• Attending specific schools in Augusta, GA area from which this study is recruiting

Exclusion Criteria:

• Unable to participate in testing or vigorous exercise program
• Diabetes
• Taking medication that would affect study results
• Sibling enrolled in project

Please refer to this study by ClinicalTrials.gov identifier  NCT00108901

Georgia
      Georgia Prevention Institute, Medical College of Georgia, Augusta,  Georgia,  30912,  United States; Recruiting

Study ID Numbers:  60692
Record last reviewed:  April 2005
Last Updated:  April 21, 2005
Record first received:  April 20, 2005
ClinicalTrials.gov Identifier:  NCT00108901
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-05-03