Genes and Gene Therapy |
Human Genome Project |
The examples and perspective in this article or section may not represent a worldwide view. Please improve the article or discuss the issue on the talk page. The Human Genome Project (HGP) is a project to map and sequence the 3 billion nucleotides contained in the human genome and to identify all the genes present in it. History and ongoing developments The Project was launched in 1986 by Charles DeLisi, who was then Director of the US Department of Energy's Health and Environmental Rese ...
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Genes and Gene Therapy Clinical Trials
- Biological Therapy and Gene Therapy in Treating Children With Recurrent or Refractory Neuroblastoma
ClinicalTrials.gov Identifier: NCT00006480 - Active, not recruiting
disseminated neuroblastoma; Drug Toxicity; recurrent neuroblastoma
- Gene Therapy in Treating Children With Refractory or Recurrent Neuroblastoma
ClinicalTrials.gov Identifier: NCT00002748 - Active, not recruiting
recurrent neuroblastoma
- Gene Therapy and Surgery Followed by Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Cancer of the Mouth or Throat
ClinicalTrials.gov Identifier: NCT00017173 - Active, not recruiting
Hypopharyngeal Cancer; Laryngeal Cancer; lip and oral cavity cancer; Oropharyngeal Cancer
- Phase I Pilot Study of Gene Therapy for Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer
ClinicalTrials.gov Identifier: NCT00004471 - Active, not recruiting
Cystic Fibrosis
- Chemotherapy With or Without Gene Therapy in Treating Patients With Unresectable Recurrent Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00040716 - Recruiting
Head and Neck Cancer
- Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
ClinicalTrials.gov Identifier: NCT00001476 - Active, not recruiting
Chronic Granulomatous Disease; Communicable Disease
- Biological Therapy in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00002786 - Active, not recruiting
Stage IV Melanoma; Recurrent Melanoma
- Comparison of Gene Therapy With Chemotherapy in Treating Patients With Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00040703 - Recruiting
Head and Neck Cancer
- Vaccine Therapy and Interleukin-2 in Treating Patients With Stage IV Kidney Cancer
ClinicalTrials.gov Identifier: NCT00031564 - Active, not recruiting
Stage IV Renal Cell Cancer
- Study of TNFerade™ gene therapy, Radiation, 5-FU and Cisplatin in Esophageal Cancer
ClinicalTrials.gov Identifier: NCT00051480 - Active, not recruiting
Esophageal Cancer
- Gene Therapy for Prostate Cancer that Returns after Radiation Therapy
ClinicalTrials.gov Identifier: NCT00110526 - Recruiting
Prostatic Neoplasms; Neoplasm Recurrence, Local
- Gene Therapy in Treating Patients With Recurrent or Progressive Glioblastoma Multiforme
ClinicalTrials.gov Identifier: NCT00036725 - Active, not recruiting
recurrent adult brain tumor; adult glioblastoma multiforme
- Medroxyprogesterone in Treating Patients With Endometrioid Adenocarcinoma of the Uterine Corpus
ClinicalTrials.gov Identifier: NCT00064025 - Recruiting
Endometrial Cancer
- Vaccine Therapy With Immune Adjuvant in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma
ClinicalTrials.gov Identifier: NCT00085137 - Active, not recruiting
Recurrent Melanoma; stage II melanoma; stage III melanoma; Stage IV Melanoma
- Interleukin-12 Gene in Treating Patients With Liver Metastases Secondary to Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00072098 - Recruiting
stage IV colon cancer; Stage IV rectal cancer; liver metastases; recurrent rectal cancer; recurrent colon cancer
- Vaccine Therapy in Treating Patients With Stage IV or Recurrent Malignant Melanoma
ClinicalTrials.gov Identifier: NCT00039325 - Active, not recruiting
Stage IV Melanoma; Recurrent Melanoma
- Gene Therapy in Treating Patients With Advanced Recurrent or Persistent Ovarian Cancer or Primary Peritoneal Cancer
ClinicalTrials.gov Identifier: NCT00003450 - Active, not recruiting
recurrent ovarian epithelial cancer; peritoneal cavity cancer; stage IV ovarian epithelial cancer
- Gene Therapy in Patients With Colon Cancer That Has Spread to the Liver
ClinicalTrials.gov Identifier: NCT00012155 - Active, not recruiting
recurrent colon cancer; liver metastases; stage IV colon cancer; adenocarcinoma of the colon
- Gene-Modified White Blood Cells Followed By Interleukin-2 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00085462 - Active, not recruiting
Melanoma (Skin)
- Gene Expression Profiling and Bioinformatic Analysis Identifying Genes and Biochemical Pathways in Type 2 Diabetes
ClinicalTrials.gov Identifier: NCT00143013 - Recruiting
Type 2 Diabetes
- Cyclophosphamide and Fludarabine Followed by Vaccine Therapy, Gene-Modified White Blood Cell Infusions, and Aldesleukin in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00091104 - Active, not recruiting
Melanoma (Skin)
- Gene Therapy in Treating Patients With Unresectable, Recurrent, or Refractory Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00004070 - Active, not recruiting
lip and oral cavity cancer; Head and Neck Cancer; Oropharyngeal Cancer
- Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) with Advate (FLrFVIII) in Hemophilia A
ClinicalTrials.gov Identifier: NCT00141843 - Active, not recruiting
Hemophilia A
- Molecular Risk Assessment in Planning Treatment for Patients With Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00055640 - Active, not recruiting
adult diffuse large cell lymphoma; childhood diffuse large cell lymphoma; childhood large cell lymphoma
- Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
ClinicalTrials.gov Identifier: NCT00005796 - Active, not recruiting
Brain Tumor
- Safety and Efficacy Study of INGN 241 Gene Therapy in Patients with In Transit Melanoma
ClinicalTrials.gov Identifier: NCT00116363 - Recruiting
Malignant Melanoma; Neoplasm Metastasis
- Trial of an Anti-HIV-1 Gene Transfer Product
ClinicalTrials.gov Identifier: NCT00074997 - Active, not recruiting
HIV Infections
- Gene Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00003942 - Active, not recruiting
AIDS-related diffuse small cleaved cell lymphoma; AIDS-related small noncleaved cell lymphoma; AIDS-related lymphoblastic lymphoma; ...
- Phase I - Pre-Radical Prostatectomy RTVP-1 Gene Therapy for Prostate Cancer
ClinicalTrials.gov Identifier: NCT00403221 - Recruiting
Prostatic Neoplasms
- Hormone Therapy in Treating Patients With Advanced Prostate Cancer
ClinicalTrials.gov Identifier: NCT00003026 - Active, not recruiting
adenocarcinoma of the prostate
- Vaccine Therapy in Treating Patients With Liver Cancer
ClinicalTrials.gov Identifier: NCT00005629 - Active, not recruiting
recurrent adult primary liver cancer; advanced adult primary liver cancer; localized resectable adult primary liver cancer; ...
- Gene Therapy in Treating Patients With Cancer
ClinicalTrials.gov Identifier: NCT00004178 - Active, not recruiting
Lung Cancer; Pancreatic Cancer; Gastric Cancer; Salivary Gland Cancer; Renal Cell Cancer; Endometrial Cancer; Esophageal Cancer; Head and Neck Cancer; ...
- Oblimersen, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
ClinicalTrials.gov Identifier: NCT00049374 - Active, not recruiting
refractory plasma cell neoplasm
- Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma
ClinicalTrials.gov Identifier: NCT00004024 - Active, not recruiting
adult brain tumor
- Gene Therapy Combined With Chemotherapy and Radiation Therapy in Treating Patients With Pancreatic Cancer That Cannot Be Surgically Removed
ClinicalTrials.gov Identifier: NCT00049647 - No longer recruiting
adenocarcinoma of the pancreas; stage III pancreatic cancer
- Gene Therapy in Treating Patients With Recurrent Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00003257 - Active, not recruiting
recurrent squamous cell carcinoma of the hypopharynx; recurrent squamous cell carcinoma of the larynx; ...
- Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00023959 - Active, not recruiting
Head and Neck Cancer
- SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
ClinicalTrials.gov Identifier: NCT00026377 - Active, not recruiting
stage II prostate cancer; stage III prostate cancer; stage IV prostate cancer; adenocarcinoma of the prostate
- Follow-Up of Patients With Breast Cancer or Multiple Myeloma Previously Treated on a Gene Therapy Clinical Trial
ClinicalTrials.gov Identifier: NCT00427726 - Active, not recruiting
Breast Cancer; Multiple Myeloma and Plasma Cell Neoplasm
- Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases
ClinicalTrials.gov Identifier: NCT00033254 - Active, not recruiting
brain metastases
- Gene-Polymorphies in the P2X7 Gene in Patients With Osteoporotic Fractures
ClinicalTrials.gov Identifier: NCT00293189 - Recruiting
Hip Fracture
- Bevacizumab and Erlotinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00055913 - Active, not recruiting
Head and Neck Cancer
- Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions
ClinicalTrials.gov Identifier: NCT00066404 - Active, not recruiting
Cancer
- Vaccine Therapy and/or Sargramostim in Treating Patients With Locally Advanced or Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00005034 - Active, not recruiting
intraocular melanoma; Melanoma
- Antibody Therapy in Treating Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00014560 - Active, not recruiting
Lymphocytic Lymphoma; Non-Hodgkin's Lymphoma
- Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00082823 - Active, not recruiting
Cancer
- Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00083213 - Active, not recruiting
Cancer
- Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00006385 - Active, not recruiting
Stage IV Melanoma; Recurrent Melanoma
- Gene Therapy for the Treatment of Brain Tumors
ClinicalTrials.gov Identifier: NCT00001328 - Active, not recruiting
Brain Neoplasm; Neoplasm Metastasis
- Gene Therapy With GX-12 in Combination With HAART for the HIV-1 Infected Patients
ClinicalTrials.gov Identifier: NCT00517569 - Recruiting
HIV Infections
- Combination Chemotherapy and Filgrastim Followed by Radiation Therapy in Treating Patients With Stage II or Stage IIIA Breast Cancer
ClinicalTrials.gov Identifier: NCT00007904 - Active, not recruiting
stage II breast cancer; stage IIIA breast cancer; Male Breast Cancer
- Gene Therapy for the Treatment of Fanconi's Anemia Type C
ClinicalTrials.gov Identifier: NCT00001399 - Active, not recruiting
Fanconi's Anemia; Pancytopenia
- Monoclonal Antibody Therapy Plus Sargramostin in Treating Patients With Advanced Neuroblastoma
ClinicalTrials.gov Identifier: NCT00002560 - Active, not recruiting
recurrent neuroblastoma
- Enzastaurin in Treating Patients With Recurrent Gliomas
ClinicalTrials.gov Identifier: NCT00112788 - Active, not recruiting
adult brain tumor
- Temozolomide and Radiation Therapy With or Without Vatalanib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov Identifier: NCT00128700 - Active, not recruiting
adult glioblastoma; adult giant cell glioblastoma; adult gliosarcoma
- Sorafenib in Treating Patients With Extensive Stage Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00182689 - Active, not recruiting
Lung Cancer
- Phase I Study Combining Suicide Gene Therapy With Chemoradiotherapy in the Treatment of Non-Metastatic Pancreatic Adenocarcinoma
ClinicalTrials.gov Identifier: NCT00415454 - Recruiting
Pancreatic Cancer
- Biological Therapy in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00045149 - Active, not recruiting
Stage IV Melanoma; Recurrent Melanoma
- Radiation Therapy With or Without Bicalutamide and Goserelin in Treating Patients With Prostate Cancer
ClinicalTrials.gov Identifier: NCT00067015 - Active, not recruiting
adenocarcinoma of the prostate; stage III prostate cancer; Quality of Life
- Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00096512 - Active, not recruiting
Head and Neck Cancer
- Trastuzumab and Imatinib Mesylate in Treating Patients With Recurrent or Metastatic HER2/neu-Expressing Cancer
ClinicalTrials.gov Identifier: NCT00084513 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Vaccine Therapy in Treating Patients With Liver Cancer
ClinicalTrials.gov Identifier: NCT00022334 - Active, not recruiting
localized resectable adult primary liver cancer; localized unresectable adult primary liver cancer; advanced adult primary liver cancer; ...
- Gene Transfer Therapy for Treating Children and Adults With Limb Girdle Muscular Dystrophy Type 2D (LGMD2D)
ClinicalTrials.gov Identifier: NCT00494195 - Recruiting
Muscular Dystrophies
- Warfarin and Vatalanib in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00091299 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Vaccine Therapy and GM-CSF in Treating Patients With Prostate Cancer That Progressed After Surgery and/or Radiation Therapy
ClinicalTrials.gov Identifier: NCT00108732 - Active, not recruiting
recurrent prostate cancer; stage I prostate cancer; stage II prostate cancer; stage III prostate cancer
- The Gene Expression Patterns in the Peripheral White Blood Cells of Type 2 Diabetic Patients
ClinicalTrials.gov Identifier: NCT00155922 - Recruiting
1. Diabetes mellitus; 2. Monocyte gene expression
- Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery
ClinicalTrials.gov Identifier: NCT00089206 - Active, not recruiting
intraocular melanoma; Melanoma
- Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme
ClinicalTrials.gov Identifier: NCT00028678 - Active, not recruiting
adult glioblastoma; adult giant cell glioblastoma; adult gliosarcoma
- Chemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients with Locally Advanced Prostate Cancer
ClinicalTrials.gov Identifier: NCT00016913 - Active, not recruiting
adenocarcinoma of the prostate; stage III prostate cancer
- Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal Tumor
ClinicalTrials.gov Identifier: NCT00006734 - Active, not recruiting
localized tumors of the Ewing's family
- Cetuximab, Combination Chemotherapy, and Radiation therapy in Treating Patients With Locally Advanced Esophageal Cancer That Cannot Be Removed By Surgery
ClinicalTrials.gov Identifier: NCT00109850 - Active, not recruiting
Adenocarcinoma of the Esophagus; squamous cell carcinoma of the esophagus; stage III esophageal cancer
- Antineoplaston Therapy in Treating Patients With Glioblastoma Multiforme
ClinicalTrials.gov Identifier: NCT00003456 - Active, not recruiting
adult glioblastoma
- Vaccine Therapy Followed by Biological Therapy in Treating Patients With Stage III or Stage IV Melanoma
ClinicalTrials.gov Identifier: NCT00006113 - Active, not recruiting
stage III melanoma; Stage IV Melanoma; Recurrent Melanoma
- Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer
ClinicalTrials.gov Identifier: NCT00003653 - Active, not recruiting
adenocarcinoma of the prostate; recurrent prostate cancer
- Calcitriol and Gefitinib With or Without Dexamethasone in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00084708 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma
ClinicalTrials.gov Identifier: NCT00104884 - Active, not recruiting
intraocular melanoma; Melanoma
- Biological Therapy Plus Monoclonal Antibody Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00040950 - Active, not recruiting
adult non-Hodgkin's lymphoma
- Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer Who Have Undergone Surgery or Radiation Therapy
ClinicalTrials.gov Identifier: NCT00054522 - Active, not recruiting
adenocarcinoma of the prostate; recurrent prostate cancer
- Vaccine Therapy Plus Interleukin-12 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
ClinicalTrials.gov Identifier: NCT00015977 - Active, not recruiting
adenocarcinoma of the prostate; stage IV prostate cancer; recurrent prostate cancer
- Androgen Suppression Plus Radiation Therapy in Treating Patients With Prostate Cancer
ClinicalTrials.gov Identifier: NCT00006359 - Active, not recruiting
adenocarcinoma of the prostate; stage I prostate cancer; stage II prostate cancer; stage III prostate cancer
- Monoclonal Antibody Therapy and/or Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer
ClinicalTrials.gov Identifier: NCT00007826 - Active, not recruiting
Colon Cancer; Rectal Cancer
- Gene Therapy for Patients with Leukocyte Adherence Deficiency (Follow-Up of Phase 1 Trial)
ClinicalTrials.gov Identifier: NCT00023010 - Active, not recruiting
Leukocyte Adhesion Deficiency Syndrome
- Graft-Versus-Host Disease in Treating Patients With Recurrent or Refractory Lymphoma or Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00003414 - Active, not recruiting
Lymphoma
- Sorafenib in Treating Patients with Stage IV Melanoma
ClinicalTrials.gov Identifier: NCT00119249 - Active, not recruiting
Stage IV Melanoma
- Doxorubicin and Paclitaxel in Treating Women Who are Undergoing Surgery For Breast Cancer
ClinicalTrials.gov Identifier: NCT00096291 - Active, not recruiting
stage II breast cancer; stage IIIA breast cancer; stage IIIB breast cancer; stage IIIC breast cancer
- Gene Therapy for Chronic Granulomatous Disease
ClinicalTrials.gov Identifier: NCT00564759 - Active, not recruiting
Granulomatous Disease, Chronic
- GW786034 in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00060151 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Combination Chemotherapy Plus Rituximab in Treating Patients With Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00005959 - Active, not recruiting
Lymphoma
- Vaccine Therapy in Treating Patients With Stage IIIB, Stage IIIC, or Stage IV Melanoma
ClinicalTrials.gov Identifier: NCT00089219 - Active, not recruiting
intraocular melanoma; Melanoma
- Vaccine Therapy and Sargramostim Compared With Placebo and Sargramostim Following Rituximab in Treating Patients With Non-Hodgkin's Lymphoma
ClinicalTrials.gov Identifier: NCT00089115 - Active, not recruiting
grade 1 follicular lymphoma; grade 2 follicular lymphoma; grade 3 follicular lymphoma
- Combination Chemotherapy in Treating Women With Stage I Breast Cancer
ClinicalTrials.gov Identifier: NCT00055679 - Active, not recruiting
stage I breast cancer
- Brief Strategic Family Therapy for Adolescent Drug Abusers - 1
ClinicalTrials.gov Identifier: NCT00095303 - Active, not recruiting
Behavior Therapy
- Radiation Therapy With or Without Cetuximab in Treating Patients With Stage III or Stage IV Cancer of the Oropharynx, Hypopharynx, or Larynx
ClinicalTrials.gov Identifier: NCT00004227 - Active, not recruiting
Oral Cancer; Throat Cancer
- Gene Therapy for Pleural Malignancies
ClinicalTrials.gov Identifier: NCT00299962 - Recruiting
Pleural Mesothelioma; Metastatic Pleural Effusions
- Epoetin alfa With or Without Dexamethasone in Treating Fatigue and Anemia in Patients With Hormone-Refractory Prostate Cancer
ClinicalTrials.gov Identifier: NCT00060398 - Active, not recruiting
recurrent prostate cancer; Anemia; Fatigue
- Celecoxib in Treating Patients With Early-Stage Head and Neck Cancer or Non-Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00058006 - Active, not recruiting
Head and Neck Cancer; thorax and respiratory cancer
- Genes Mutation Pentalogy of Cantrell
ClinicalTrials.gov Identifier: NCT00477932 - Recruiting
Pentalogy of Cantrell; Mutations in Non-Muscle Genes
- Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
ClinicalTrials.gov Identifier: NCT00005044 - Active, not recruiting
adenocarcinoma of the prostate; stage II prostate cancer; stage III prostate cancer
- Sorafenib in Treating Patients With Advanced Soft Tissue Sarcomas
ClinicalTrials.gov Identifier: NCT00217620 - Active, not recruiting
adult soft tissue sarcoma
- Oral Combination Chemotherapy in Treating Elderly Patients With Intermediate or High-Grade Non-Hodgkin's Lymphomas
ClinicalTrials.gov Identifier: NCT00003113 - Active, not recruiting
Lymphoma

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