Pulmonary Hypertension Clinical Trials

• ARIES - Ambrisentan in Patients with Moderate to Severe Pulmonary Arterial Hypertension (PAH)
  ClinicalTrials.gov Identifier: NCT00091598 - Active, not recruiting
  Pulmonary Hypertension
  
• PHIRST-1: Safety and Efficacy of Tadalafil in the Treatment of Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00125918 - Active, not recruiting
  Pulmonary Hypertension
  
• Study of BSF 208075 evaluating exercise capacity in patients with pulmonary arterial hypertension
  ClinicalTrials.gov Identifier: NCT00046319 - Active, not recruiting
  Pulmonary Hypertension
  
• Endothelial Cell Dysfunction in Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00098072 - Recruiting
  Hypertension, Pulmonary
  
• Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00034307 - Active, not recruiting
  Pulmonary Hypertension
  
• A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children with Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00159913 - Recruiting
  Pulmonary Hypertension
  
• Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH)
  ClinicalTrials.gov Identifier: NCT00310830 - Active, not recruiting
  Pulmonary Hypertension
  
• Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH)
  ClinicalTrials.gov Identifier: NCT00313196 - Active, not recruiting
  Pulmonary Hypertension
  
• Phase 2 Study of Ambrisentan for Liver Function Test Rescue in Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00423592 - Active, not recruiting
  Pulmonary Hypertension
  
• Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
  ClinicalTrials.gov Identifier: NCT00319111 - Active, not recruiting
  Pulmonary Hypertension
  
• Bosentan in Children With Pulmonary Arterial Hypertension Extension Study
  ClinicalTrials.gov Identifier: NCT00319020 - Active, not recruiting
  Pulmonary Hypertension
  
• Phase 2 Extension Study of Ambrisentan in Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00424021 - Active, not recruiting
  Pulmonary Hypertension
  
• Safety and Effectiveness of PRX-08066 in Patients With Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease
  ClinicalTrials.gov Identifier: NCT00345774 - Active, not recruiting
  Pulmonary Hypertension; Chronic Obstructive Pulmonary Disease
  
• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess Safety and Efficacy of Ambrisentan in Subjects With Pulmonary Arterial Hypertension.
  ClinicalTrials.gov Identifier: NCT00423202 - Active, not recruiting
  Pulmonary Arterial Hypertension
  
• Inhaled Nitric Oxide and Transfusion Therapy for Patients with Sickle Cell Anemia and Secondary Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00023296 - Active, not recruiting
  Sickle Cell Anemia; Pulmonary Hypertension
  
• Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults
  ClinicalTrials.gov Identifier: NCT00581087 - Not yet recruiting
  Chronic Obstructive Pulmonary Disease; Hypertension, Pulmonary
  
• Study to Assess Safety and Efficacy of Ambrisentan in Subjects With Pulmonary Arterial Hypertension.
  ClinicalTrials.gov Identifier: NCT00423748 - Active, not recruiting
  Pulmonary Arterial Hypertension
  
• NO Need to Ventilate: A Trial of Non-Invasive Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn
  ClinicalTrials.gov Identifier: NCT00139217 - Recruiting
  Pulmonary Hypertension
  
• A Transition Study From Flolan® to Remodulin® in Patients with Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00058929 - Completed
  Pulmonary Arterial Hypertension; Pulmonary Hypertension
  
• Safety, Efficacy and Treatment Satisfaction in Patients With Pulmonary Arterial Hypertension Rapidly Switched From Epoprostenol to Remodulin
  ClinicalTrials.gov Identifier: NCT00373360 - Recruiting
  Pulmonary Hypertension
  
• The “VISION” Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00302211 - Recruiting
  Pulmonary Hypertension
  
• Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00323297 - Recruiting
  Pulmonary Hypertension
  
• Genetic Research of Bone Morphogenetic Protein Receptor-II Gene in Taiwanese Patient With Primary Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00173537 - Recruiting
  Pulmonary Hypertension
  
• Inhaled Prostacyclin for ARDS and Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00314548 - Recruiting
  Adult Respiratory Distress Syndrome; Pulmonary Hypertension
  
• FREEDOM - M: Oral Treprostinil as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)
  ClinicalTrials.gov Identifier: NCT00325403 - Recruiting
  Pulmonary Hypertension
  
• Cardiopulmonary Function Assessment and NO-Based Therapies for Patients With Hemolysis-Associated Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00352430 - Recruiting
  Pulmonary Hypertension
  
• Long-Term Observational Study of Ventavis in Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00250640 - Recruiting
  Primary Pulmonary Hypertension
  
• Open Label Study of Sildenafil in Patients With Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00454207 - Recruiting
  Pulmonary Hypertension
  
• An Open Multiple Dose Titration Study In Patients With Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00454558 - Recruiting
  Hypertension, Pulmonary
  
• Open Label Extension Study Evaluating Sildenafil Citrate When Used In Combination with Epoprostenol In PAH
  ClinicalTrials.gov Identifier: NCT00147641 - Active, not recruiting
  Pulmonary Hypertension
  
• FREEDOM-C: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor for the Treatment of Pulmonary Arterial Hypertension (PAH)
  ClinicalTrials.gov Identifier: NCT00325442 - Recruiting
  Pulmonary Hypertension
  
• A Long Term Study of Ambrisentan in Pulmonary Arterial Hypertension Subjects Having Completed AMB-320 or AMB-321
  ClinicalTrials.gov Identifier: NCT00578786 - Active, not recruiting
  Pulmonary Arterial Hypertension
  
• Gene Mutations in Secondary Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00348803 - Recruiting
  Chronic Thromboembolic Pulmonary Hypertension
  
• Safety and Efficacy Study of Ambrisentan in Subjects With Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00380068 - Recruiting
  Pulmonary Hypertension
  
• The Effect of Tracleer™ on Male Fertility
  ClinicalTrials.gov Identifier: NCT00082186 - Active, not recruiting
  Hypertension, Pulmonary
  
• Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria
  ClinicalTrials.gov Identifier: NCT00367523 - Recruiting
  Secondary Pulmonary Arterial Hypertension; Sickle Cell Disease; Pulmonary Hypertension
  
• Serotonin Transporter Inhibitor Escitalopram in Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00190333 - Recruiting
  Pulmonary Hypertension
  
• A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00384865 - Recruiting
  Hypertension, Pulmonary
  
• Is There Intravascular Hemolysis in Patients With Pulmonary Hypertension?
  ClinicalTrials.gov Identifier: NCT00502398 - Recruiting
  Pulmonary Artery Hypertension
  
• Safety Study of Gleevec® in Children With Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00583115 - Recruiting
  Pulmonary Hypertension
  
• Trial of Iloprost Inhaled Solution as Add-On Therapy with Bosentan in Subjects with Pulmonary Arterial Hypertension (PAH)
  ClinicalTrials.gov Identifier: NCT00086463 - Completed
  Pulmonary Arterial Hypertension; PAH; Pulmonary Hypertension
  
• Iloprost-Study: Comparison of Nitric Oxide to Iloprost (Ventavis) for Treatment of Pulmonary Hypertension in Children After Cardiopulmonary Bypass Surgery
  ClinicalTrials.gov Identifier: NCT00235521 - Recruiting
  Pulmonary Hypertension
  
• Magnetic Resonance Imaging in the Diagnosis of Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00575692 - Recruiting
  Pulmonary Hypertension; Ventricular Function; MR Phase Contrast Velocity Imaging; Late Enhancement Patterns
  
• Multi-Center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma Patients
  ClinicalTrials.gov Identifier: NCT00377949 - Recruiting
  Systemic Sclerosis; Scleroderma; Pulmonary Hypertension
  
• Latent PH in CTEPH After Endarterectomy and Influence of Exercise and Respiratory Therapy
  ClinicalTrials.gov Identifier: NCT00477724 - Recruiting
  Latent Pulmonary Hypertension; Chronic Thromboembolic Pulmonary Hypertension
  
• Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)
  ClinicalTrials.gov Identifier: NCT00303459 - Recruiting
  Pulmonary Hypertension
  
• N-Terminal Pro-Brain Natriuretic Peptide Hormone and Persistent Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00443859 - Recruiting
  Persistent Pulmonary Hypertension of Newborn
  
• Natrecor for Pulmonary Hypertension in Lung Transplants
  ClinicalTrials.gov Identifier: NCT00205426 - Recruiting
  Pulmonary Hypertension
  
• Pulmonary Hypertension: Assessment of Cell Therapy
  ClinicalTrials.gov Identifier: NCT00469027 - Recruiting
  Hypertension, Pulmonary
  
• Exercise and Respiratory Therapy in Patients With Rheumatoid Arthritis / Collagenosis and Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00491309 - Recruiting
  Pulmonary Hypertension; Exercise
  
• Evaluate the Efficacy, Safety and Pharmacokinetics of GSK1325760A in the Treatment of Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00540436 - Recruiting
  Pulmonary Arterial Hypertension
  
• Study of the Efficacy and Safety of Tezosentan in Patients With Pre-Operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart Surgery
  ClinicalTrials.gov Identifier: NCT00458276 - Recruiting
  Heart Diseases; Hypertension, Pulmonary
  
• Inhaled Iloprost for the Treatment of Persistent Pulmonary Hypertension in the Term and Near Term Infants.
  ClinicalTrials.gov Identifier: NCT00409526 - Recruiting
  Pulmonary Hypertension
  
• Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH)
  ClinicalTrials.gov Identifier: NCT00452218 - Recruiting
  Pulmonary Arterial Hypertension
  
• Safety and Efficacy of Imatinib Mesylate in Patients With Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00477269 - Recruiting
  Pulmonary Arterial Hypertension
  
• Simvastatin as a Treatment for Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00180713 - Recruiting
  Pulmonary Hypertension
  
• To Assess The Efficacy And Safety Of Oral Sildenafil In The Treatment Of Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00430716 - Not yet recruiting
  Hypertension, Pulmonary
  
• A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study
  ClinicalTrials.gov Identifier: NCT00360087 - Active, not recruiting
  Pulmonary Hypertension; Sickle Cell Anemia
  
• Endothelial Progenitor Cells and Pulmonary Idiopathic Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00551408 - Active, not recruiting
  Pulmonary Idiopathic Arterial Hypertension
  
• Long Term Extension Study Evaluating Safety of Sildenafil Citrate When Used to Treat PAH in Children
  ClinicalTrials.gov Identifier: NCT00159874 - Recruiting
  Pulmonary Hypertension
  
• Combination Therapy of Bosentan and Aerosolized Iloprost in Idiopathic Pulmonary Arterial Hypertension (IPAH)
  ClinicalTrials.gov Identifier: NCT00120380 - Active, not recruiting
  Hypertension
  
• Trial of Iloprost in Pulmonary Hypertension Secondary to Pulmonary Fibrosis
  ClinicalTrials.gov Identifier: NCT00439543 - Not yet recruiting
  Pulmonary Fibrosis; Pulmonary Hypertension
  
• Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis
  ClinicalTrials.gov Identifier: NCT00359736 - Recruiting
  Fibrosis, Pulmonary; Alveolitis, Fibrosing; Hypertension, Pulmonary; Exercise, Aerobic
  
• Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients with Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00080457 - Completed
  Pulmonary Hypertension
  
• Efficacy of Type-5 Phosphodiesterase Inhibitors in Primary and Secondary Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00155714 - Recruiting
  primary and secondary pulmonary hypertension
  
• Inhaled Iloprost in Adults with Abnormal Pulmonary Pressure and Associated with Idiopathic Pulmonary Fibrosis
  ClinicalTrials.gov Identifier: NCT00109681 - Completed
  Pulmonary Fibrosis; Pulmonary Hypertension
  
• Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00372346 - Recruiting
  Idiopathic Pulmonary Arterial Hypertension
  
• Inhaled Iloprost for Sarcoidosis Associated Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00403650 - Recruiting
  Sarcoidosis; Pulmonary Arterial Hypertension
  
• 6R-BH4 Pulmonary Arterial Hypertension Study
  ClinicalTrials.gov Identifier: NCT00435331 - Recruiting
  Pulmonary Arterial Hypertension
  
• Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis
  ClinicalTrials.gov Identifier: NCT00517933 - Recruiting
  Pulmonary Fibrosis; Hypertension, Pulmonary
  
• Efficacy and Safety of Oral Bosentan in Pulmonary Arterial Hypertension Class II
  ClinicalTrials.gov Identifier: NCT00091715 - Completed
  Pulmonary Hypertension
  
• Treatment of Elevated Arterial Pulmonary Pressure with Inhaled Iloprost.
  ClinicalTrials.gov Identifier: NCT00216931 - Recruiting
  Persistent Pulmonary Hypertension; Respiratory Distress Syndrome
  
• Genetic and Environmental Pathogenesis of PPH
  ClinicalTrials.gov Identifier: NCT00091546 - Recruiting
  Lung Diseases; Hypertension, Pulmonary
  
• Double Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00581607 - Not yet recruiting
  Sarcoidosis; Pulmonary Arterial Hypertension
  
• Effect of Iloprost on Gas Exchange and Pulmonary Mechanics in Patients With COPD in Patients With COPD
  ClinicalTrials.gov Identifier: NCT00561223 - Recruiting
  Chronic Obstructive Pulmonary Disease; Pulmonary Hypertension
  
• Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery?
  ClinicalTrials.gov Identifier: NCT00334490 - Recruiting
  Pulmonary Hypertension
  
• Combination Therapy in Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00433329 - Recruiting
  Pulmonary Arterial Hypertension
  
• Clinical Investigation Into the Efficacy and Tolerability of Inhaled Treprostinil Sodium in Patients with Severe PAH
  ClinicalTrials.gov Identifier: NCT00147199 - Recruiting
  Pulmonary Arterial Hypertension
  
• Pulmonary Hypertension, Hypoxia and Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00495638 - Recruiting
  Chuvash Polycythemia; Cerebrovascular Disease; Pulmonary Hypertension; Sickle Cell Anemia
  
• Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia
  ClinicalTrials.gov Identifier: NCT00260819 - Recruiting
  Hypoxia-Induced Pulmonary Artery Hypertension
  
• Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00352482 - Completed
  Pulmonary Fibrosis; Hypertension, Pulmonary
  
• Study to Assess the Longterm Safety of Sildenafil Citrate in Patients with Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00159887 - Completed
  Pulmonary Hypertension
  
• Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00350844 - Recruiting
  Sickle Cell Disease; Pulmonary Hypertension
  
• Simvatstatin Used to Treat Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00538044 - Not yet recruiting
  Hypertension, Pulmonary
  
• Secondary Pulmonary Hypertension in Adults with Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00011648 - Recruiting
  Pulmonary Hypertension; Sickle Cell Anemia
  
• A Study of Aspirin and Clopidogrel in Patients with Idiopathic Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00105209 - Completed
  Hypertension, Pulmonary
  
• Sildenafil Effects on Pulmonary Haemodynamics and Gas Exchange in COPD
  ClinicalTrials.gov Identifier: NCT00491803 - Recruiting
  COPD; Pulmonary Hypertension
  
• Study of Inhaled Nitric Oxide for Preterm Infants
  ClinicalTrials.gov Identifier: NCT00016523 - Active, not recruiting
  Respiratory Distress Syndrome; Infant, Premature; Sepsis; Pneumonia; Hypertension, Pulmonary
  
• Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease
  ClinicalTrials.gov Identifier: NCT00492531 - Recruiting
  Sickle Cell Disease; Pulmonary Hypertension
  
• Rehabilitation for Patients With Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00544726 - Not yet recruiting
  Pulmonary Arterial Hypertension
  
• Bosentan in Treatment of Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00266162 - Active, not recruiting
  Eisenmenger Syndrome
  
• Pulmonary Hypertension in Trisomy 21 Patients
  ClinicalTrials.gov Identifier: NCT00478296 - Active, not recruiting
  Congenital Disorders
  
• Safety Follow-up Study of Inhaled Iloprost in Patients With Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00185315 - Completed
  Pulmonary Hypertension
  
• Spironolactone Combined With Captopril and Carvedilol for the Treatment of Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00240656 - Completed
  Hypertension, Pulmonary
  
• Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00004754 - Completed
  Hypertension, Pulmonary
  
• Chronic Sildenafil for Severe Diaphragmatic Hernia
  ClinicalTrials.gov Identifier: NCT00133679 - Recruiting
  Hernia, Diaphragmatic; Hypertension, Pulmonary; Hypoplasia, Lung
  
• Pulmonary Hypertension--Mechanisms and Family Registry
  ClinicalTrials.gov Identifier: NCT00005357 - Completed
  Lung Diseases; Hypertension, Pulmonary
  
• BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
  ClinicalTrials.gov Identifier: NCT00367770 - Completed
  Pulmonary Arterial Hypertension
  
• Phase III Randomized Study of UT-15 in Patients with Primary Pulmonary Hypertension
  ClinicalTrials.gov Identifier: NCT00004497 - Completed
  Pulmonary Hypertension
  
• Bosentan in Children With Pulmonary Arterial Hypertension
  ClinicalTrials.gov Identifier: NCT00319267 - Completed
  Pulmonary Hypertension