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Impact of nCPAP Treatment on Liver Function in Patients with Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis - Article


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General Topics A-Z

Sleep Apnea

Apnea; Apnea, Sleep

Clinical Trial: Impact of nCPAP Treatment on Liver Function in Patients with Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis

This study is currently recruiting patients.
Verified by University Hospital Angers September 2005

Sponsored by: University Hospital Angers
Information provided by: University Hospital Angers
ClinicalTrials.gov Identifier: NCT00152711

Purpose

This study aims to evaluate the impact of nCPAP treatment on liver enzymes in patients with sleep apnea syndrome and nonalcoholic steatohepatitis. Using a cross over design, the evolution of liver enzymes will be evaluate in 40 patients during to consecutive periodes of 6 weeks, with and without nCPAP treatment.
Condition Intervention
Sleep Apnea Syndrome
Nonalcoholic steatohepatitis
  Device: nCPAP

MedlinePlus related topics:  Sleep Apnea

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Uncontrolled, Expanded Access Assignment

Official Title: Impact of nCPAP Treatment on Liver Function in Patients with Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis: a Prospective Cross Over Trial.

Further Study Details: 

Expected Total Enrollment:  40

Study start: September 2004

Eligibility

Ages Eligible for Study:  18 Years   -   70 Years,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

18 to 70 years old Nonalcoholic steatohepatitis proven by liver biopsy Sleep apnea syndrome proven by polysomnography with an apnea-hypopnea index > 10 events/h Informed consent

Exclusion Criteria:

Psychiatric disorder Other cause of liver disease Professional driver

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00152711

Frédéric Gagnadoux, MD      33(0)241353695    frgagnadoux@chu-angers.fr

Study chairs or principal investigators

Frédéric Gagnadoux,  Principal Investigator,  UH Angers   

More Information

Study ID Numbers:  PHRC 03-07
Last Updated:  September 8, 2005
Record first received:  September 8, 2005
ClinicalTrials.gov Identifier:  NCT00152711
Health Authority: France: French General Health Administration
ClinicalTrials.gov processed this record on 2005-09-13


Source: ClinicalTrials.gov
Cache Date: September 14, 2005


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