Not Signed In -
Sarcoma, Ewing's Family of Tumors |
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Clinical Trial: Diagnostic Study of Tumor Characteristics in Patients With Ewing's Sarcoma
This study is currently recruiting patients.
Purpose
RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to plan more effective therapy.
PURPOSE: Diagnostic trial to study genetic differences in patients who have Ewing's sarcoma.
| Condition | Treatment or Intervention |
|---|---|
| localized tumors of the Ewing's family metastatic tumors of the Ewing's family recurrent tumors of the Ewing's family | Procedure: chromosomal translocation Procedure: cytogenetic analysis Procedure: diagnostic test Procedure: mutation analysis Procedure: proteomic profiling Procedure: reverse transcriptase-polymerase chain reaction |
MedlinePlus related topics: Bone Cancer
Study Type: Interventional
Study Design: Diagnostic
Further Study Details:
OBJECTIVES:
- Determine the prognostic significance of chromosomal translocation subtype in patients with Ewing's sarcoma.
- Determine the prognostic significance of minimal residual disease detection in bone marrow of these patients, using reverse transcriptase-polymerase chain reaction determination of EWS-ETS fusion genes.
- Determine whether serum levels of IGF1 and IGFBP3 are of significance to outcome of these patients.
- Establish clinical proteomics for investigating altered signaling molecules in the pathogenesis of Ewing's sarcoma.
OUTLINE: This is a multicenter study.
Patients undergo various specimen collections, including bone marrow aspirate, paraffin-embedded blocks of tumor tissue or slides of tumor tissue, and blood specimens. These specimens are collected before, during, and after any chemotherapy regimens, during follow-up, and at time of recurrence. Translocation studies are performed on specimens to identify fusion genes, specifically EWS-ETS. Serum IGF1 and IFGBP3 levels are determined. Bone marrow is assessed for minimal residual disease using reverse-transcriptase polymerase chain reaction.
PROJECTED ACCRUAL: A total of 470 patients will be accrued for this study within 4 years.
Eligibility
Ages Eligible for Study: up to 50 Years, Genders Eligible for Study: Both
Criteria
DISEASE CHARACTERISTICS:
- Newly diagnosed or recurrent Ewing's sarcoma
- Availability of the following specimens:
- Paraffin-embedded block or 20 unstained slides and 1-3 thick (50 micron) sections from initial biopsy
- Pretreatment serum and whole blood
- Concurrent therapy is not required
PATIENT CHARACTERISTICS: Age
- 50 and under
Performance status
- Not specified
Life expectancy
- Not specified
Hematopoietic
- Not specified
Hepatic
- Not specified
Renal
- Not specified
PRIOR CONCURRENT THERAPY: Biologic therapy
- Not specified
Chemotherapy
- Not specified
Endocrine therapy
- Not specified
Radiotherapy
- Not specified
Surgery
- Not specified
Location and Contact Information
Alabama
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, 35233, United States; Recruiting
Robert P. Castleberry, MD 205-939-9285 rcastleberry@peds.uab.edu
University of South Alabama Cancer Research Institute, Mobile, Alabama, 36604, United States; Recruiting
Felicia L. Wilson, MD 251-405-5115 fwilson@usouthal.edu
Arizona
Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona, 85724, United States; Recruiting
Rochelle Bagatell, MD 520-626-4851
Phoenix Children's Hospital, Phoenix, Arizona, 85016, United States; Recruiting
Dale Anne Singer, MD 602-546-0920
Arkansas
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, 72205, United States; Recruiting
David L. Becton, MD 501-320-5650
California
Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center, Orange, California, 92868, United States; Recruiting
Stanley Calderwood, MD 714-456-6615 scalderw@uci.edu
Children's Hospital and Health Center, San Diego, San Diego, California, 92123-4282, United States; Recruiting
Richard Kadota, MD 858-966-5811
Children's Hospital and Research Center at Oakland, Oakland, California, 94609-1809, United States; Recruiting
James H. Feusner, MD 510-428-3000 jfeusner@mail.cho.org
Children's Hospital Central California, Madera, California, 93638-8762, United States; Recruiting
Vonda Lee Crouse, MD 559-353-5480 vcrouse@childrenscentralcal.org
Children's Hospital Los Angeles, Los Angeles, California, 90027-0700, United States; Recruiting
Paul S. Gaynon, MD 323-669-2163 pgaynon@chla.usc.edu
Children's Hospital of Orange County, Orange, California, 92868, United States; Recruiting
Wei-Ping Violet Shen, MD 714-516-4348 vshen@choc.org
City of Hope Comprehensive Cancer Center, Duarte, California, 91010-3000, United States; Recruiting
Clinical Trials Office - New Patient Services 800-826-4673 becomingapatient@coh.org
General Robert Huyser Cancer Center at David Grant Medical Center, Travis Air Force Base, California, 94535, United States; Recruiting
Peter J. Chenaille, MD 707-423-7176
Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach, California, 90801-1428, United States; Recruiting
William Mark Roberts, MD 562-933-8600 wmroberts@memorialcare.org
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, 90095-1781, United States; Recruiting
Stephen A. Feig, MD 310-825-5268
Kaiser Permanente Medical Center - Sacramento, Sacramento, California, 95825, United States; Recruiting
Vincent A. Kiley, MD 916-973-7331 vincent.kiley@kp.org
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, 95051-5386, United States; Recruiting
Carolyn Lucille Russo, MD 408-236-5028 carolyn.l.russo@kp.org
Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego, San Diego, California, 92120, United States; Recruiting
Wellington Loh, MD 619-516-6144
Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda, California, 92354, United States; Recruiting
Antranik Bedros, MD 909-558-8626 abedro@ahs.llumc.edu
Lucile Packard Children's Hospital at Stanford University Medical Center, Palo Alto, California, 94304, United States; Recruiting
Neyssa M. Marina, MD 650-723-5535 neyssa.marina@stanford.edu
Rebecca and John Moores UCSD Cancer Center, La Jolla, California, 92093-0658, United States; Recruiting
Richard Kadota, MD 858-657-7020
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angeles, California, 90048, United States; Recruiting
Moshe Arditi, MD 310-423-4471
Santa Barbara Cottage Hospital, Santa Barbara, California, 93102, United States; Recruiting
Felicity Hodder, MD 805-682-7111 fhodder@cottagehealthsystem.org
Southern California Permanente Medical Group, Downey, California, 90242, United States; Recruiting
Willye B. Powell, MD 562-803-2472
Sutter Cancer Center, Sacramento, California, 95816, United States; Recruiting
Yisheng Lee, MD, PhD, MBA 916-733-1757
UCSF Comprehensive Cancer Center, San Francisco, California, 94143, United States; Recruiting
Katherine K. Matthay, MD 415-476-3831
University of California Davis Cancer Center, Sacramento, California, 95817, United States; Recruiting
Daniel C. West, MD 916-734-2428 dcwest@ucdavis.edu
Colorado
Children's Hospital Cancer Center, Denver, Colorado, 80218, United States; Recruiting
Roger Howard Giller, MD 303-861-6892 giller.roger@tchden.org
Presbyterian - St. Luke's Medical Center, Denver, Colorado, 80218, United States; Recruiting
Stephen R. Palmer, MD 719-471-2462
Connecticut
Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center, Farmington, Connecticut, 06360-7106, United States; Recruiting
Arnold J. Altman, MD 860-545-9630
Yale Comprehensive Cancer Center, New Haven, Connecticut, 06520-8064, United States; Recruiting
Jack van Hoff, MD 203-785-4640 jack.vanhoff@yale.edu
Delaware
Alfred I. duPont Hospital for Children, Wilmington, Delaware, 19899, United States; Recruiting
Rita S. Meek, MD 302-651-5502 rmeek@nemours.org
District of Columbia
Children's National Medical Center, Washington, District of Columbia, 20010-2970, United States; Recruiting
Nita Louise Seibel, MD 202-884-2144 nseibel@cnmc.org
Lombardi Cancer Center at Georgetown University Medical Center, Washington, District of Columbia, 20007, United States; Recruiting
Aziza Shad, MD 202-444-2224 shada@georgetown.edu
Florida
All Children's Hospital, St. Petersburg, Florida, 33701, United States; Recruiting
Jerry L. Barbosa, MD 727-892-4231 barbosaj@allkids.org
Baptist-South Miami Regional Cancer Program, Miami, Florida, 33176-2197, United States; Recruiting
Doured Daghistani, MD 786-596-1960
Broward General Medical Center, Fort Lauderdale, Florida, 33316, United States; Recruiting
Rudolph R. Roskos, MD 954-355-4527 rroskos@nbhd.org
Children's Hospital of Southwest Florida, Fort Myers, Florida, 33908, United States; Recruiting
Emad K. Salman, MD 239-432-3333 emad.salman@leememorial.org
Florida Hospital Cancer Institute, Orlando, Florida, 32804, United States; Recruiting
Jane Crofton, RN, BSN, OCN 407-303-2090
Jackson Memorial Hospital, Miami, Florida, 33136, United States; Recruiting
Stuart R. Toledano, MD 305-585-5635 stoledan@med.miami.edu
Joe DiMaggio Children's Hospital at Memorial, Hollywood, Florida, 33021, United States; Recruiting
Iftikhar Hanif, MD 954-986-2234 ifhanif@aol.com
Miami Children's Hospital, Miami, Florida, 33155, United States; Recruiting
Enrique A. Escalon, MD 305-666-6511
Nemours Children's Clinic, Jacksonville, Florida, 32207, United States; Recruiting
Eric Sandler, MD 904-390-3793 esandler@nemours.org
Nemours Children's Clinic-Orlando, Orlando, Florida, 32806, United States; Recruiting
Vincent F. Giusti, MD 407-650-7230
Sacred Heart Children's Hospital, Pensacola, Florida, 32504, United States; Recruiting
John F. Kelleher, MD 850-505-4798 jfkelleh@neumous.org
St. Joseph's Children's Hospital, Tampa, Florida, 33677-4227, United States; Recruiting
Cameron K. Tebbi, MD 813-870-4252 cameron.tebbi@baycare.org
St. Mary's Hospital, West Palm Beach, Florida, 33407, United States; Recruiting
Narayana Gowda, MD 561-840-6125 doctorgowda@hotmail.com
University of Florida Shands Cancer Center, Gainesville, Florida, 32610-0296, United States; Recruiting
Stephen P. Hunger, MD 352-392-5633 hungersp@peds.ufl.edu
Georgia
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus, Atlanta, Georgia, 30342, United States; Recruiting
Howard M. Katzenstein, MD 404-785-0853 howard.katzenstein@choa.org
Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center, Savannah, Georgia, 31405, United States; Recruiting
Tribhawan S. Vats, MD 912-350-8194 vatsri@memorialhealth.com
MBCCOP-Medical College of Georgia Cancer Center, Augusta, Georgia, 30912-4000, United States; Recruiting
Roger A. Vega, MD 706-721-3626
Medical Center of Central Georgia, Macon, Georgia, 31201, United States; Recruiting
Hassan Dannawi, MD 478-633-1104 dannawi.hassan@mccg.org
Hawaii
Cancer Research Center of Hawaii, Honolulu, Hawaii, 96813, United States; Recruiting
Robert Warren Wilkinson, MD 808-586-2979
MBCCOP - Hawaii, Honolulu, Hawaii, 96813, United States; Recruiting
Brian F. Issell, MD 808-586-3015 brian@crch.hawaii.edu
Tripler Army Medical Center, Honolulu, Hawaii, 96859-5000, United States; Recruiting
Braden Alan Shoupe, MD 808-433-6057
Idaho
Mountain States Tumor Institute - Boise, Boise, Idaho, 83712, United States; Recruiting
J. Martin Johnston, MD 208-381-2782 johnstom@slrmc.org
Illinois
Advocate Hope Children's Hospital, Oak Lawn, Illinois, 60453, United States; Recruiting
Sharad N. Salvi, MD 708-346-4094 sharad.salvi@advocatehealth.com
Children's Memorial Hospital - Chicago, Chicago, Illinois, 60614, United States; Recruiting
Susan Lerner Cohn, MD 773-880-4562
Lutheran General Cancer Care Center, Park Ridge, Illinois, 60068-1174, United States; Recruiting
Jong-Hyo Kwon, MD 847-723-5962 jong-hyo.kwon_md@advocatehealth.com
Rush University Medical Center, Chicago, Illinois, 60612, United States; Recruiting
Allen D. Korenblit, MD 312-942-5983 akorenbl@rush.edu
Saint Jude Midwest Affiliate, Peoria, Illinois, 61637, United States; Recruiting
John A. McCallister, MD 309-624-4945 john.mccallister@stjude.org
Southern Illinois University School of Medicine, Springfield, Illinois, 62794-9658, United States; Recruiting
Gregory Brandt, MD 217-545-5817 gbrandt@siumed.edu
University of Chicago Cancer Research Center, Chicago, Illinois, 60601, United States; Recruiting
James B. Nachman, MD 773-702-6808
University of Illinois Medical Center, Chicago, Illinois, 60612, United States; Recruiting
Mary Lou Schmidt, MD 312-996-6143 mls3@uic.edu
Indiana
Riley Children Cancer Center at Riley Hospital for Children, Indianapolis, Indiana, 46202-5225, United States; Recruiting
Robert Fallon, MD, PhD 317-274-8784 rfallon@iupui.edu
St. Vincent Hospitals and Health Care Centers, Indianapolis, Indiana, 46260, United States; Recruiting
Randy Alan Hock, MD, PhD, MMM 317-338-4673
Iowa
Blank Children's Hospital, Des Moines, Iowa, 50309, United States; Recruiting
Stephen C. Elliott, DO, PhD, FAAP 515-241-6000 elliotsc@ihs.org
Holden Comprehensive Cancer Center at University of Iowa, Iowa City, Iowa, 52242-1009, United States; Recruiting
Raymond Tannous, MD 319-356-1905
Kansas
Wesley Medical Center, Wichita, Kansas, 67214, United States; Recruiting
David Rosen, MD 316-962-2025
Kentucky
Kosair Children's Hospital, Louisville, Kentucky, 40202-3830, United States; Recruiting
Salvatore J. Bertolone, MD 502-852-8450
Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington, Kentucky, 40536-0284, United States; Recruiting
Martha F. Greenwood, MD 859-323-6771 mfgree0@pop.uky.edu
Louisiana
Children's Hospital of New Orleans, New Orleans, Louisiana, 70118, United States; Recruiting
Lolie Chua Yu, MD 504-896-9740
MBCCOP - LSU Health Sciences Center, New Orleans, Louisiana, 70112, United States; Recruiting
Jill Gilbert, MD 504-568-5613 jgilbe@lsuhsc.edu
Ochsner Cancer Institute at Ochsner Clinic Foundation, New Orleans, Louisiana, 70121, United States; Recruiting
Marquis Zimri Hodes, MD, PhD 504-842-5230
Tulane Cancer Center at Tulane University Hospital and Clinic, New Orleans, Louisiana, 70112, United States; Recruiting
Marshall A. Schorin, MD 504-988-5412 mschori@tulane.edu
Maine
CancerCare of Maine at Eastern Maine Medial Center, Bangor, Maine, 04401, United States; Recruiting
Judith B. Allen, MD 207-973-7520
Maine Children's Cancer Program, Scarborough, Maine, 04074-9308, United States; Recruiting
Craig A. Hurwitz, MD 207-885-7565 hurwic@mmc.org
Maryland
Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore, Maryland, 21215, United States; Recruiting
Joseph Michael Wiley, MD 410-601-5864 jwiley@lifebridehealth.org
Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, 21201-1595, United States; Recruiting
Neil Jeffrey Grossman, MD 410-328-2808 ngrossma@peds.umaryland.edu
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, 21231-2410, United States; Recruiting
Cindy Schwartz, MD 410-955-7385 schwac@ijhmi.edu
Walter Reed Army Medical Center, Silver Spring, Maryland, 20910, United States; Recruiting
Kip R. Hartman, MD 301-319-9116
Massachusetts
Baystate Regional Cancer Program at D'Amour Center for Cancer Care, Springfield, Massachusetts, 01107, United States; Recruiting
David A. Steele, MD 413-794-9338 david.steele@bhs.org
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, 02115, United States; Recruiting
Holcombe Edwin Grier, MD 617-632-3971 holcombe-grier@dfci.harvard.edu
Floating Hospital for Children, Boston, Massachusetts, 02111, United States; Recruiting
Cynthia S. Kretschmar, MD 617-636-5535 ckretschmar@tufts-nemc.org
UMASS Memorial Cancer Center - University Campus, Worcester, Massachusetts, 01655, United States; Recruiting
Ghazala Naheed Usmani, MD 508-856-4225 usmanin@ummhc.org
Michigan
Breslin Cancer Center at Ingham Regional Medical Center, Lansing, Michigan, 48910, United States; Recruiting
Renuka Gera, MD 517-334-2337
Bronson Methodist Hospital, Kalamazoo, Michigan, 49007-5364, United States; Recruiting
Leonard August Mattano, MD, PhD 616-341-6350
CCOP - Beaumont, Royal Oak, Michigan, 48073-6769, United States; Recruiting
Jeanne Archer, PhD, APN 248-551-8299 carcher@beaumon.edu
Children's Hospital of Michigan, Detroit, Michigan, 48201, United States; Recruiting
Yaddanapudi Ravindranath, MBBS 313-745-5649 ravi@med.wayne.edu
DeVos Children's Hospital, Grand Rapids, Michigan, 49503, United States; Recruiting
David Robert Freyer, DO 616-391-2086
Hurley Medical Center, Flint, Michigan, 48503, United States; Recruiting
Susumu Inoue, MD 810-762-7303 sinoue1@hurleymc.com
Josephine Ford Cancer Center at Henry Ford Health System, Detroit, Michigan, 48202, United States; Recruiting
Hassan M. Yaish, MD 313-916-3138
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, 48109-0914, United States; Recruiting
Raymond J. Hutchinson, MD 734-936-8785
Van Elslander Cancer Center at St. John Hospital and Medical Center, Detroit, Michigan, 48236, United States; Recruiting
Hadi Sawaf, MD 313-647-3200 hadi.sawaf@stjohn.org
William Beaumont Hospital - Royal Oak, Royal Oak, Michigan, 48073-6769, United States; Recruiting
Charles A. Main, MD 248-551-0360
Minnesota
Children's Hospitals and Clinics - Minneapolis/St. Paul, Minneapolis, Minnesota, 55404, United States; Recruiting
Maura C. O'Leary, MD 612-813-5940
Mayo Clinic Cancer Center, Rochester, Minnesota, 55905, United States; Recruiting
Carola A.S. Arndt, MD 507-284-2511 carndt@mayo.edu
St. Mary's - Duluth Clinic Cancer Center, Duluth, Minnesota, 55805, United States; Recruiting
Jacquelyn Dawn Wiermaa, MD 218-786-3625
Mississippi
University of Mississippi Medical Center, Jackson, Mississippi, 39216-4505, United States; Recruiting
Dale Jeanette Pullen, MD 601-984-5220
Missouri
Cardinal Glennon Children's Hospital, Saint Louis, Missouri, 63104, United States; Recruiting
William Shay Ferguson, MD 314-577-5638
Children's Mercy Hospital, Kansas City, Missouri, 64108, United States; Recruiting
Maxine L. Hetherington, MD 816-234-3265
St. Louis Children's Hospital, Saint Louis, Missouri, 63110, United States; Recruiting
Robert James Hayashi, MD 314-454-4118 hayashi_r@kids.wustl.edu
University of Missouri - Columbia, Columbia, Missouri, 65203, United States; Recruiting
Barbara Anne Gruner, MD 573-882-3961 grunerb@health.missousri.edu
Nebraska
Children's Hospital of Omaha, Omaha, Nebraska, 68114, United States; Recruiting
Minnie Abromowitch, MD 402-955-3949 mabromo@unmc.edu
UNMC Eppley Cancer Center at the University of Nebraska Medical Center, Omaha, Nebraska, 68198-2168, United States; Recruiting
Peter F. Coccia, MD 402-559-7257 pcoccia@unmc.edu
Nevada
Sunrise Hospital and Medical Center, Las Vegas, Nevada, 89109, United States; Recruiting
Jonathan Bernstein, MD 702-732-0971 jonbern1@aol.com
New Hampshire
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, 03756, United States; Recruiting
Eric Christian Larsen, MD 603-650-5541 eric.c.larsen@hitchcock.org
New Jersey
Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, 07601, United States; Recruiting
Michael B. Harris, MD 201-996-5437 mbharris@humed.com
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick, New Jersey, 08903, United States; Recruiting
Richard A. Drachtman, MD 732-235-5437 drachtri@umdnj.edu
Newark Beth Israel Medical Center, Newark, New Jersey, 07112-2094, United States; Recruiting
Peri Kamalakar, MD 973-926-7161 pkamalak@sghcs.com
St. Joseph's Hospital and Medical Center, Paterson, New Jersey, 07503, United States; Recruiting
Mary Ann Bonilla, MD 973-754-3230 bonillam@sjhmc.org
Valerie Fund Children's Center at Atlantic Health, Summit, New Jersey, 07901, United States; Recruiting
Hazem Helmy Mahmoud, MD 973-971-6731
New Mexico
University of New Mexico Cancer Research and Treatment Center, Albuquerque, New Mexico, 87131, United States; Recruiting
Jami Frost, MD 505-272-4461
New York
Albert Einstein Cancer Center at Albert Einstein College of Medicine, Bronx, New York, 10461, United States; Recruiting
Eva Radel, MD 718-920-7844
Brookdale University Hospital and Medical Center, Brooklyn, New York, 11212, United States; Recruiting
Kusum Viswanathan, MD 718-240-5904
Brooklyn Hospital Center, Brooklyn, New York, 11201-5493, United States; Recruiting
Swayamprabha Sadanandan, MD 718-250-6074 sws9001@nyp.org
Cancer Center of Albany Medical Center, Albany, New York, 12208, United States; Recruiting
Jennifer M. Pearce, MD 518-262-5513 pearcej@mail.amc.edu
Comprehensive Cancer Center at Maimonides Medical Center, Brooklyn, New York, 11219, United States; Recruiting
Ludovico Guarini, MD 718-283-8173 lguarini@maimonidesmed.org
Herbert Irving Comprehensive Cancer Center at Columbia University, New York, New York, 10032, United States; Recruiting
Linda Granowetter, MD 212-305-8652 lg519@columbia.edu
James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester, New York, 14642, United States; Recruiting
Barbara Lawrence Asselin, MD 716-275-2981
Long Island Cancer Center at Stony Brook University Hospital, Stony Brook, New York, 11794, United States; Recruiting
Robert Ingalls Parker, DSc 631-444-4000
Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, United States; Recruiting
Peter G. Steinherz, MD 212-639-7951
Mount Sinai School of Medicine, New York, New York, 10029, United States; Recruiting
Elizabeth Raetz, MD 212-241-7022
New York Medical College, Valhalla, New York, 10595, United States; Recruiting
M. Fevzi Ozkaynak, MD 914-493-7997 mehmet_ozkaynak@nymc.edu
New York Weill Cornell Cancer Center at Cornell University, New York, New York, 10021, United States; Recruiting
Patricia J.V. Giardina, MD 212-746-3400
Schneider Children's Hospital, New Hyde Park, New York, 11042, United States; Recruiting
Arlene Sara Redner, MD 718-470-3460
SUNY Downstate Medical Center, Brooklyn, New York, 11203, United States; Recruiting
Sreedhar P. Rao, MD 718-270-1693
SUNY Upstate Medical University Hospital, Syracuse, New York, 13210, United States; Recruiting
Ronald L. Dubowy, MD 315-464-5294 dubowyr@upstate.edu
North Carolina
Blumenthal Cancer Center at Carolinas Medical Center, Charlotte, North Carolina, 28232-2861, United States; Recruiting
Daniel P. McMahon, MD 704-355-1130 dmcmahon@carolinas.org
Comprehensive Cancer Center at Wake Forest University, Winston Salem, North Carolina, 27157-1081, United States; Recruiting
Thomas Williams McLean, MD 336-716-4324
Duke Comprehensive Cancer Center, Durham, North Carolina, 27710, United States; Recruiting
Philip Paul Breitfeld, MD 919-684-3377
Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital, Greenville, North Carolina, 27858-4354, United States; Recruiting
Charles W. Daeschner, MD 252-744-4676 DaeschnerC@mail.ecu.edu
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill, North Carolina, 27599, United States; Recruiting
Stuart Gold, MD 919-966-0985 stubaby@med.unc.med
Mission Hospitals, Asheville, North Carolina, 28801, United States; Recruiting
Orren Beaty, DO, PhD 823-213-5770 orren.beaty@msj.org
Presbyterian Cancer Center at Presbyterian Hospital, Charlotte, North Carolina, 28233, United States; Recruiting
Mark Mogul, MD 704-384-1900
North Dakota
Dakota Cancer Institute at Innovis Health - Dakota Clinic, Fargo, North Dakota, 58103-4940, United States; Recruiting
Janet K. Tillisch, MD 701-364-4964
Ohio
Children's Hospital Medical Center of Akron, Akron, Ohio, 44308-1062, United States; Recruiting
Steven J. Kuerbitz, MD 330-543-8730 skuerbitz@chmca.org
Children's Medical Center - Dayton, Dayton, Ohio, 45404, United States; Recruiting
Emmett H. Broxson, MD, FAAP 937-641-3111 broxsone@childrensdayton.org
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229-3039, United States; Recruiting
John Peter Perentesis, MD 513-636-6090
Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, 44195, United States; Recruiting
Karen A. Bringelsen, MD 216-444-7923
Columbus Children's Hospital, Columbus, Ohio, 43205-2696, United States; Recruiting
Amanda Termuhlen, MD 614-722-3552
Forum Health-Tod Childrens Hospital, Youngstown, Ohio, 44501, United States; Recruiting
Ayman Saleh, MD, FAAP 330-884-3955 asaleh@neoucom.edu
Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio, 44106-5065, United States; Recruiting
Susan Wiersma, MD 216-844-3345 srw3@po.cwru.edu
St. Vincent Mercy Medical Center, Toledo, Ohio, 43608, United States; Recruiting
Rama Jasty, MD 419-251-8215 rjasty@mco.edu
Toledo Children's Hospital, Toledo, Ohio, 43601, United States; Recruiting
Richard M. Shore, MD 419-471-5437
Oklahoma
CCOP - Oklahoma, Tulsa, Oklahoma, 74136, United States; Recruiting
James B. Lockhart, MD 918-491-5878
Children's Hospital at Oklahoma University Medical Center, Oklahoma City, Oklahoma, 73104, United States; Recruiting
William H. Meyer, MD 405-271-5311 william-meyer@ouhsc.edu
Natalie Warren Bryant Cancer Center at St. Francis Hospital, Tulsa, Oklahoma, 74136, United States; Recruiting
Martina Christine Hum, MD 918-494-2525 pedonc@saintfrancis.com
Oregon
CCOP - Columbia River Oncology Program, Portland, Oregon, 97225, United States; Recruiting
Keith S. Lanier, MD 503-216-6260
Doernbecher Children's Hospital at Oregon Health & Science University, Portland, Oregon, 97239-3098, United States; Recruiting
H. Stacy Nicholson, MD, MPH 503-494-1543
Legacy Emanuel Hospital and Health Center & Children's Hospital, Portland, Oregon, 97227, United States; Recruiting
Janice Faye Olson, MD 503-413-2200
Pennsylvania
Children's Hospital at Milton S. Hershey Medical Center, Hershey, Pennsylvania, 17033, United States; Recruiting
John E. Neely, MD 717-531-6012 jen6@psu.edu
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, United States; Recruiting
Richard Berry Womer, MD 215-590-2229 rwomer@mail.med.upenn.edu
Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United States; Recruiting
Arthur Kim Ritchey, MD 412-692-5055 kim.ritchey@chp.edu
Geisinger Medical Center, Danville, Pennsylvania, 17822-1320, United States; Recruiting
Jeffrey Taylor, MD 570-271-6848
St. Christopher's Hospital for Children, Philadelphia, Pennsylvania, 19134-1095, United States; Recruiting
Gregory E. Halligan, MD 215-427-5000 Gregory.Halligan@tenethealth.com
Rhode Island
Rhode Island Hospital, Providence, Rhode Island, 02903, United States; Recruiting
Sam W. Lew, MD 401-444-5171
South Carolina
Children's Hospital of Greenville Hospital System, Greenville, South Carolina, 29605, United States; Recruiting
Cary Ernest Stroud, MD 864-455-8898
Hollings Cancer Center at Medical University of South Carolina, Charleston, South Carolina, 29425-0721, United States; Recruiting
Julio C. Barredo, MD 843-792-2957 barredjc@musc.edu
Palmetto Health South Carolina Cancer Center, Columbia, South Carolina, 29203, United States; Recruiting
Ronnie W. Neuberg, MD 803-434-3533 ronnie.neuberg@palmettohealth.org
South Dakota
Avera Cancer Institute, Sioux Falls, South Dakota, 57105-1080, United States; Recruiting
Marwan D. Hanna, MD 605-322-7595
Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls, South Dakota, 57117-5039, United States; Recruiting
Jakica Tancabelic, MD 605-333-7171 jtancabe@usd.edu
Tennessee
East Tennessee Children's Hospital, Knoxville, Tennessee, 37901, United States; Recruiting
Ray C. Pais, MD 865-541-8266 hemonc@etch.com
East Tennessee State University Cancer Center at Johnson City Medical Center, Johnson City, Tennessee, 37614-0622, United States; Recruiting
David K. Kalwinsky, MD 423-433-6200 sjcrhta@msha,cin
St. Jude Children's Research Hospital, Memphis, Tennessee, 38105-2794, United States; Recruiting
Wayne Lee Furman, MD 901-495-3300
Vanderbilt Children's Hospital, Nashville, Tennessee, 37232-6310, United States; Recruiting
James A. Whitlock, MD 615-936-1762
Texas
Baylor College of Medicine, Houston, Texas, 77030, United States; Recruiting
C. Philip Steuber, MD 713-798-6970
CCOP - Scott and White Hospital, Temple, Texas, 76508, United States; Recruiting
Lucas Wong, MD 254-724-1053 lwong@swmail.sw.org
Center for Cancer Prevention and Care at Scott and White Clinic, Temple, Texas, 76508, United States; Recruiting
Dick Suh, MD, PhD 254-724-9852 DSuh@swmail.sw.org
Children's Hospital of Austin, Austin, Texas, 78701, United States; Recruiting
Sharon K. Lockhart, MD 512-324-8480 slockhart@stcaustin.com
Cook Children's Medical Center - Fort Worth, Fort Worth, Texas, 76104, United States; Recruiting
Timothy C. Griffin, MD 682-885-4020 TGriffin@cookchildrens.org
Covenant Children's Hospital, Lubbock, Texas, 79410, United States; Recruiting
John Iacuone, MD 806-725-4840
MBCCOP - South Texas Pediatrics, San Antonio, Texas, 78229-3900, United States; Recruiting
Anne-Marie Langevin, MD 210-704-3405 langevin@uthscsa.edu
MD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4009, United States; Recruiting
Joann Ater, MD 713-792-6665 jater@mdanderson.org
Medical City Dallas Hospital, Dallas, Texas, 75230, United States; Recruiting
Carl Lenarsky, MD 972-566-6647 carl.lenarsky@usoncology.com
Methodist Cancer Center at Methodist Specialty and Transplant Hospital, San Antonio, Texas, 78229-3902, United States; Recruiting
Jaime Estrada, MD 210-575-8130
San Antonio Military Pediatric Cancer and Blood Disorders Center, Lackland Air Force Base, Texas, 78236, United States; Recruiting
Aaron Pitney, MD 210-292-5684
Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas, Texas, 75390-9063, United States; Recruiting
Naomi J. Winick, MD 214-648-3074 naomi.winick@utsouthwestern.edu
Texas Tech University Health Sciences Center School of Medicine, Amarillo, Texas, 79106, United States; Recruiting
Curtis Wade Turner, MD 806-354-5434 curtis.turner@ttuhsc.edu
University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78207, United States; Recruiting
Paul Jan Thomas, MD 210-704-3405 thomasp@uthscsa.edu
University of Texas Medical Branch, Galveston, Texas, 77555-0209, United States; Recruiting
Frederick Szujuei Huang, MD 409-772-2341 fshuang@utmb.edu
Utah
Huntsman Cancer Institute at University of Utah, Salt Lake City, Utah, 84112, United States; Recruiting
Carol S. Bruggers, MD 801-585-0303
Vermont
Vermont Cancer Center at University of Vermont, Burlington, Vermont, 05401-3498, United States; Recruiting
Alan C. Homans, MD 802-847-2850
Virginia
Cancer Center at the University of Virginia, Charlottesville, Virginia, 22908, United States; Recruiting
Kimberly Dunsmore, MD 434-924-9333
Carilion Medical Center for Children at Roanoke Community Hospital, Roanoke, Virginia, 24029, United States; Recruiting
Joan Mistretta Fisher, MD, PhD 540-985-8055 jmfisher@carilion.com
Children's Hospital of the King's Daughters, Norfolk, Virginia, 23507, United States; Recruiting
Rebecca L. Byrd, MD 757-668-7243 byrdrl@chkd.org
INOVA Fairfax Hospital, Falls Church, Virginia, 22042-3300,
More Information
Clinical trial summary from the National Cancer Institute's PDQ® database
Study ID Numbers: CDR0000257115; COG-AEWS02B1; NCI-03-C-0216; NCT00048984
Record last reviewed: May 2004
Last Updated: April 4, 2005
Record first received: November 12, 2002
ClinicalTrials.gov Identifier: NCT00048984
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Record last reviewed: May 2004
Last Updated: April 4, 2005
Record first received: November 12, 2002
ClinicalTrials.gov Identifier: NCT00048984
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
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