Familial Periodic Paralyses Clinical Trials

• IL-1 Trap for Treatment of CIAS1 Associated Periodic Syndromes (CAPS)
  ClinicalTrials.gov Identifier: NCT00288704 - Active, not recruiting
  Familial Cold Autoinflammatory Syndrome; Familial Cold Urticaria; Muckle-Wells Syndrome; Genetic Diseases, Inborn
  
• Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics
  ClinicalTrials.gov Identifier: NCT00001373 - Recruiting
  Periodic Disease
  
• Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders
  ClinicalTrials.gov Identifier: NCT00004802 - Completed
  Paralysis, Hyperkalemic Periodic; Hypokalemic Periodic Paralysis; Paramyotonia Congenita
  
• Hyper- and Hypokalemic Periodic Paralysis Study
  ClinicalTrials.gov Identifier: NCT00494507 - Recruiting
  Periodic Paralysis
  
• The Effect of Diflunisal on Familial Amyloidosis
  ClinicalTrials.gov Identifier: NCT00294671 - Recruiting
  Familial Amyloid Polyneuropathy; Familial Amyloidosis
  
• Study of ISIS 301012 in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy
  ClinicalTrials.gov Identifier: NCT00281008 - Active, not recruiting
  Hypercholesterolemia, Familial
  
• Dose-Escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy
  ClinicalTrials.gov Identifier: NCT00280995 - Active, not recruiting
  Hypercholesterolemia, Familial
  
• Effect of TAK-475 or Placebo co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia
  ClinicalTrials.gov Identifier: NCT00263081 - Active, not recruiting
  Hypercholesterolemia, Familial
  
• Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism
  ClinicalTrials.gov Identifier: NCT00465751 - Recruiting
  Metabolic Syndrome; Familial Hypertriglyceridemia; Familial Combined Hyperlipidemia
  
• Bone Marrow Stem Cells as a Source of Allogenic Hepatocyte Transplantation in Homozygous Familial Hypercholesterolemia
  ClinicalTrials.gov Identifier: NCT00515307 - Recruiting
  Hypercholesterolemia, Familial
  
• Open Label Extension of ISIS 301012 to Treat Familial Hypercholesterolemia
  ClinicalTrials.gov Identifier: NCT00477594 - Recruiting
  Familial Hypercholesterolemia
  
• Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined Hyperlipidemia
  ClinicalTrials.gov Identifier: NCT00005313 - Active, not recruiting
  Atherosclerosis; Cardiovascular Diseases; Heart Diseases; Hypercholesterolemia; Hyperlipidemia, Familial Combined
  
• Chemoprevention Trial in Familial Adenomatous Polyposis Coli Using EPA
  ClinicalTrials.gov Identifier: NCT00510692 - Active, not recruiting
  Familial Adenomatous Polyposis Coli; FAP
  
• Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus Ezetimibe
  ClinicalTrials.gov Identifier: NCT00475826 - Recruiting
  Heterozigous Familial Hypercholesterolemia
  
• Understanding the Genetic Basis of Familial Combined Hyperlipidemia in Mexican Individuals
  ClinicalTrials.gov Identifier: NCT00365235 - Recruiting
  Hyperlipidemia, Familial Combined; Coronary Disease
  
• Multimedia Intervention in Patients With Familial Adenomatous Polyposis (FAP)
  ClinicalTrials.gov Identifier: NCT00525655 - Recruiting
  Familial Adenomatous Polyposis; Colorectal Cancer
  
• Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients
  ClinicalTrials.gov Identifier: NCT00248053 - Recruiting
  Familial Adenomatous Polyposis
  
• Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine
  ClinicalTrials.gov Identifier: NCT00541736 - Recruiting
  Familial Hemiplegic Migraine
  
• Screening For Early Pancreatic Neoplasia in Individuals With Familial Peutz-Jeghers Syndrome and in Relatives of Individuals With Familial Pancreatic Cancer
  ClinicalTrials.gov Identifier: NCT00084357 - Active, not recruiting
  Pancreatic Cancer
  
• The Use of Kineret (Anakinra) in the Treatment of Familial Cold Urticaria
  ClinicalTrials.gov Identifier: NCT00214851 - Recruiting
  Familial Cold Urticaria
  
• Genomic Dissection of a QTL Affecting the Lipid Profile
  ClinicalTrials.gov Identifier: NCT00064688 - Active, not recruiting
  Cardiovascular Diseases; Heart Diseases; Obesity; Hyperlipidemia, Familial Combined
  
• Clinical and Genetic Studies of Familial Presenile Dementia with Neuronal Inclusion Bodies
  ClinicalTrials.gov Identifier: NCT00006176 - Recruiting
  Familial Dementia with Neuroserpin Inclusion Bodies; Nervous System Heredodegenerative Disorder
  
• Investigational Drug in Patients with Hypercholesterolemia or in Patients with Sitosterolemia
  ClinicalTrials.gov Identifier: NCT00092833 - Active, not recruiting
  Hypercholesterolemia, Familial; Lipid Metabolism, Inborn Errors
  
• Inflammatory Proteins in Familial Mediterranean Fever During Attack and Remission
  ClinicalTrials.gov Identifier: NCT00323440 - Not yet recruiting
  Familial Mediterranean Fever
  
• IL-1 Trap for Treatment of Familial Mediterranean Fever (FMF)
  ClinicalTrials.gov Identifier: NCT00582907 - Not yet recruiting
  Familial Mediterranean Fever
  
• PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin
  ClinicalTrials.gov Identifier: NCT00355615 - Active, not recruiting
  Familial Hypercholesterolemia
  
• Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders
  ClinicalTrials.gov Identifier: NCT00006056 - Active, not recruiting
  Chediak-Higashi Syndrome; Graft Versus Host Disease; X-Linked Lymphoproliferative Syndrome; Familial Erythrophagocytic Lymphohistiocytosis; ...
  
• Intermittent and Daily Dosing for Episodic (Periodic) Asthma
  ClinicalTrials.gov Identifier: NCT00337675 - Recruiting
  Asthma
  
• A Study of Familial and Genetic Aspects of Adult T-Cell: Leukemia/Lymphoma , Tropical Spastic Paraparesis, and Infective Dermatitis
  ClinicalTrials.gov Identifier: NCT00340821 - Active, not recruiting
  HTLV-I
  
• Internleukin-1 Trap to Treat Autoinflammatory Disease
  ClinicalTrials.gov Identifier: NCT00094900 - Recruiting
  Inflammation; Familial Mediterranean Fever; Still's Disease, Adult-Onset
  
• Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis
  ClinicalTrials.gov Identifier: NCT00409175 - Completed
  Familial Amyloid Polyneuropathy
  
• Clinical and Molecular Characterization of Familial Microsatellite Stable Colorectal Cancer
  ClinicalTrials.gov Identifier: NCT00220246 - Active, not recruiting
  Colorectal Neoplasms
  
• Study for Treatment of Moderate or Severe, Periodic, "Cyclic", Breast Pain
  ClinicalTrials.gov Identifier: NCT00237523 - Active, not recruiting
  Fibrocystic Disease of Breast; Fibrocystic Changes of Breast; Fibrocystic Mastopathy; Pain
  
• Effects of Acetazolamide and CO2 Inhalation on Exercise-Induced Periodic Breathing in Heart Failure
  ClinicalTrials.gov Identifier: NCT00517426 - Recruiting
  Chronic Heart Failure
  
• Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia
  ClinicalTrials.gov Identifier: NCT00134485 - Completed
  Hypercholesterolemia, Familial; Hyperlipidemia
  
• Genetic Analysis of Thyrotoxic Periodic Paralysis
  ClinicalTrials.gov Identifier: NCT00443833 - Completed
  Thyrotoxic Periodic Paralysis
  
• Carotid IMT (Intima Media Thickening) Study
  ClinicalTrials.gov Identifier: NCT00384293 - Recruiting
  Hypercholesterolemia, Familial
  
• Parental Involvement and Children's Extra-Familial Contexts
  ClinicalTrials.gov Identifier: NCT00538252 - Recruiting
  Prevention of Drug Abuse Risk
  
• Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy
  ClinicalTrials.gov Identifier: NCT00253812 - Recruiting
  Familial Adenomatous Polyposis
  
• Celecoxib in Treating Patients With Familial Adenomatous Polyposis
  ClinicalTrials.gov Identifier: NCT00258219 - Recruiting
  Colorectal Cancer; Precancerous/Nonmalignant Condition
  
• Effectiveness of Paricalcitol in Reducing Parathyroid Hormone Levels in X-Linked Hypophosphatemic Rickets
  ClinicalTrials.gov Identifier: NCT00417612 - Recruiting
  Hypophosphatemia, Familial; Hyperparathyroidism
  
• Molecular Targeting of 15-LOX-1 for Apoptosis Induction in Human Colorectal Cancers
  ClinicalTrials.gov Identifier: NCT00503035 - Recruiting
  Familial Adenomatous Polyposis
  
• Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia
  ClinicalTrials.gov Identifier: NCT00004809 - Completed
  Familial Hypercholesterolemia
  
• Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency
  ClinicalTrials.gov Identifier: NCT00260299 - Recruiting
  Mevalonic Aciduria; Mevalonate Kinase Deficiency; Immune System Diseases; Periodic Fever Syndromes, Hereditary; Lipid Metabolism, Inborn Errors
  
• Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.
  ClinicalTrials.gov Identifier: NCT00358839 - Completed
  Familial Hemiplegic Migraine
  
• A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression
  ClinicalTrials.gov Identifier: NCT00091871 - Recruiting
  Eosinophilia
  
• Effect of Vitamin D and Calcium on Genes in the Colon
  ClinicalTrials.gov Identifier: NCT00298545 - Recruiting
  Pre-Cancerous Colorectal Polyps; Familial Colorectal Adenoma; Adenocarcinoma
  
• Genetic Analysis of Familial Keloids
  ClinicalTrials.gov Identifier: NCT00008502 - Recruiting
  Keloid
  
• Johnston County ADHD Study: Environmental, Reporductive, and Familial Risk Factors for Attention-Deficit Hyperactivity Disorder (ADHD)
  ClinicalTrials.gov Identifier: NCT00339729 - Active, not recruiting
  Attention-Deficit Hyperactivity Disorder
  
• Study of Novel Types of Familial Diabetes Insipidus
  ClinicalTrials.gov Identifier: NCT00004364 - Active, not recruiting
  Diabetes Insipidus
  
• Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders
  ClinicalTrials.gov Identifier: NCT00582621 - Recruiting
  Lymphoma; Leukemia; Multiple Myeloma; Colon Cancer; Renal Cancer
  
• Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia
  ClinicalTrials.gov Identifier: NCT00171236 - Completed
  Heterozygous Familial Hypercholesterolemia; Mixed Dyslipidemia
  
• Genetic Analysis of Familial Melanoma
  ClinicalTrials.gov Identifier: NCT00339404 - Recruiting
  Melanoma
  
• Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol Disorder
  ClinicalTrials.gov Identifier: NCT00134511 - Completed
  Hypercholesterolemia, Familial
  
• Influence of Sulindac and Probiotics on the Development of Pouch Adenomas in Patients With Familial Adenomatous Polyposis
  ClinicalTrials.gov Identifier: NCT00319007 - Recruiting
  Adenomatous Polyposis Coli
  
• Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome
  ClinicalTrials.gov Identifier: NCT00565903 - Recruiting
  Pleuropulmonary Blastoma; Cystic Nephroma
  
• Comparative 2-D Tumor Analysis in Familial Gliomas
  ClinicalTrials.gov Identifier: NCT00125710 - Recruiting
  -malignant glioma
  
• Implitapide in Patients with Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy
  ClinicalTrials.gov Identifier: NCT00079859 - Terminated
  Familial Hypercholesterolemia
  
• Implitapide in Patients with Homozygous Familial Hypercholesterolemia (HoFH) on Maximal Concurrent Lipid-Lowering Therapy
  ClinicalTrials.gov Identifier: NCT00079846 - Terminated
  Familial Hypercholesterolemia
  
• Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis
  ClinicalTrials.gov Identifier: NCT00393016 - Recruiting
  Colorectal Cancer; Precancerous/Nonmalignant Condition
  
• Natural History Study of Patients With Excess Androgen
  ClinicalTrials.gov Identifier: NCT00250159 - Recruiting
  Excess Androgen; Congenital Adrenal Hyperplasia (CAH); Familial Male-Limited Precocious Puberty (FMPP)
  
• Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2
  ClinicalTrials.gov Identifier: NCT00257985 - Completed
  Familial Hemiplegic Migraine Type 1 and 2; Healthy Volunteers
  
• Early Onset and Familial Gastric Cancer Registry
  ClinicalTrials.gov Identifier: NCT00582257 - Recruiting
  Gastric Cancer
  
• Exisulind in Preventing Polyps in Patients With Familial Adenomatous Polyposis
  ClinicalTrials.gov Identifier: NCT00026468 - Active, not recruiting
  Colon Cancer; Rectal Cancer; small intestine cancer
  
• Familial Aggregation and Natural History of Sleep Apnea
  ClinicalTrials.gov Identifier: NCT00005299 - Active, not recruiting
  Lung Diseases; Sleep Apnea Syndromes
  
• Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers
  ClinicalTrials.gov Identifier: NCT00579163 - Recruiting
  Breast Neoplasms; Ovarian Neoplasms; Colonic Neoplasms; Prostatic Neoplasms; Uterine Cervical Neoplasms; Leukemia; Lymphoma, Non-Hodgkin
  
• Cinacalcet to Treat Familial Primary Hyperparathyroidism
  ClinicalTrials.gov Identifier: NCT00325104 - Completed
  Hypercalcemia; Familial Primary Hyperparathyroidism
  
• Familial Barrett's Esophagus
  ClinicalTrials.gov Identifier: NCT00288119 - Recruiting
  Barrett's Esophagus; Esophageal Neoplasm
  
• Familial Intracranial Aneurysm Study
  ClinicalTrials.gov Identifier: NCT00071565 - Active, not recruiting
  Intracranial Aneurysm; Subarachnoid Hemorrhage
  
• Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis
  ClinicalTrials.gov Identifier: NCT00382369 - Recruiting
  Vocal Cord Paralysis
  
• Genetic Epidemiology of Familial Amyotrophic Lateral Sclerosis (ALS)
  ClinicalTrials.gov Identifier: NCT00317616 - Recruiting
  Amyotrophic Lateral Sclerosis
  
• Genetics of Familial Testicular Cancer
  ClinicalTrials.gov Identifier: NCT00342537 - Recruiting
  Testicular Cancer
  
• Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrapib/Atorvastatin to Atorvastatin Alone.
  ClinicalTrials.gov Identifier: NCT00136981 - Completed
  Hypercholesterolemia, Familial; Hyperlipidemia
  
• Circadian Rhythms and Sleep in Familial Delayed Sleep Phase Syndrome (DSPS) and Advanced Sleep Phase Syndrome (ASPS)
  ClinicalTrials.gov Identifier: NCT00246454 - Recruiting
  Sleep
  
• Familial Amyotrophic Lateral Sclerosis. A Preliminary Study to Identify Subjects Who Might Be Willing to Participate in a Randomized Controlled Trial
  ClinicalTrials.gov Identifier: NCT00136500 - Recruiting
  Amyotrophic Lateral Sclerosis
  
• Analysis of Genomic DNA Alterations in Familial Schizophrenia
  ClinicalTrials.gov Identifier: NCT00166738 - Recruiting
  Schizophrenia; Chinese Han People
  
• Clinical and Genetic Studies of Familial Exudative Vitreoretinopathy
  ClinicalTrials.gov Identifier: NCT00106756 - Recruiting
  Exudatiaon; Avascular Retina; Retina Fold
  
• Study of the Cause of Familial Testicular Cancer
  ClinicalTrials.gov Identifier: NCT00034424 - Recruiting
  Testicular Neoplasms; Germinoma
  
• The Genetic Basis for Familial Cardiomyopathy in Patients With Idiopathic Cardiomyopathy
  ClinicalTrials.gov Identifier: NCT00322582 - Not yet recruiting
  Cardiomyopathy
  
• TRIAL OF ASPIRIN AND ARGININE RESTRICTION IN FAMILIAL COLON CANCER
  ClinicalTrials.gov Identifier: NCT00578721 - Not yet recruiting
  Colon Cancer
  
• Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis.
  ClinicalTrials.gov Identifier: NCT00033371 - Recruiting
  Colon Cancer; Rectal Cancer
  
• Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
  ClinicalTrials.gov Identifier: NCT00006054 - Active, not recruiting
  Immunologic Deficiency Syndromes; Chediak-Higashi Syndrome; Common Variable Immunodeficiency; Graft Versus Host Disease; ...
  
• Characteristics of Idiopathic Familial Voice Disorders
  ClinicalTrials.gov Identifier: NCT00001552 - Recruiting
  Laryngeal Disease; Spastic Dysphonia; Voice Disorder
  
• Characteristics of Idiopathic Familial Speech Disorders
  ClinicalTrials.gov Identifier: NCT00001551 - Recruiting
  Developmental Articulation Disorder; Speech Disorder; Stuttering
  
• Evaluating Tools for Health Promotion and Disease Prevention
  ClinicalTrials.gov Identifier: NCT00164658 - Recruiting
  Coronary Heart Disease; Stroke; Diabetes; Breast Cancer; Ovarian Cancer; Colorectal Cancer
  
• Internal and Familial Resources and Motherhood. Follow Up of Mothers With Twins and Preterm Infants Versus Mothers With Single Full Term Infants
  ClinicalTrials.gov Identifier: NCT00320840 - Not yet recruiting
  Twins; Preterm Infants
  
• Genetic Epidemiology of Hypertriglyceridemia
  ClinicalTrials.gov Identifier: NCT00005368 - Completed
  Cardiovascular Diseases; Coronary Disease; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type IV
  
• NHLBI Type II Coronary Intervention Study
  ClinicalTrials.gov Identifier: NCT00000594 - Completed
  Cardiovascular Diseases; Coronary Disease; Heart Diseases; Hypercholesterolemia, Familial; Myocardial Infarction; Myocardial Ischemia
  
• Genetic Study of Familial Factors in Patients With Colon Cancer
  ClinicalTrials.gov Identifier: NCT00055848 - Recruiting
  adenocarcinoma of the colon; stage I colon cancer; stage II colon cancer; stage III colon cancer; stage IV colon cancer
  
• Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.
  ClinicalTrials.gov Identifier: NCT00151788 - Terminated
  Atherosclerosis; Heterozygous familial hypercholesterolemia
  
• Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis
  ClinicalTrials.gov Identifier: NCT00035334 - Completed
  Secondary (AA) Amyloidosis; Rheumatoid Arthritis; Nephrotic Syndrome; Familial Mediterranean Syndrome; Kidney Diseases; Gastrointestinal Diseases
  
• Hyperapo B and Coronary Heart Disease
  ClinicalTrials.gov Identifier: NCT00005168 - Completed
  Cardiovascular Diseases; Coronary Disease; Heart Diseases; Diabetes Mellitus; Obesity; Hypercholesterolemia, Familial
  
• A Study to Compare the Use of Fluconazole as Continuous Therapy Versus Periodic Therapy in HIV-Positive Patients with Recurrent Thrush
  ClinicalTrials.gov Identifier: NCT00000951 - Completed
  Candidiasis, Oral; HIV Infections
  
• Genetic Analysis of Familial Brain Aneurysms
  ClinicalTrials.gov Identifier: NCT00011856 - Completed
  Intracranial Aneurysm
  
• A Study of Ezetimibe Plus Simvastatin in Adolescents With Heterozygous Familial Hypercholesterolemia
  ClinicalTrials.gov Identifier: NCT00129402 - Completed
  Hypercholesterolemia
  
• Genetic Study of Familial Epilepsy
  ClinicalTrials.gov Identifier: NCT00006059 - Completed
  Epilepsy
  
• Study of Pituitary Size and Function in Familial Dwarfism of Sindh
  ClinicalTrials.gov Identifier: NCT00004365 - Completed
  Growth Hormone Deficiency
  
• Pilot Study of Familial Nonsyndromal Mondini Dysplasia
  ClinicalTrials.gov Identifier: NCT00004336 - Completed
  Mondini dysplasia
  
• Gender Differences in Familial Risk
  ClinicalTrials.gov Identifier: NCT00005355 - Completed
  Cardiovascular Diseases; Heart Diseases
  
• Familial Aggregation of Stress Response
  ClinicalTrials.gov Identifier: NCT00005428 - Completed
  Cardiovascular Diseases; Heart Diseases; Hypertension