Olivopontocerebellar Atrophy |
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Olivopontocerebellar atrophy (OPCA) are a group of diseases characterized by neuronal degeneration in the cerebellum, pontine nuclei, and inferior olive. They are also referred to as spinocerebellar ataxias (SCA) or atrophies. Some also involve brain stem motor nuclei and/or cerebral cortex. All produce gait ataxia, and some also result in tremors, proprioceptive abnormalities, dysarthria, brain stem motor impairment, or dementia. Most are autosomal dominant in inheritance pattern. The prim ...
Wikipedia - [full article]
Olivopontocerebellar Atrophy Clinical Trials
- A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy
ClinicalTrials.gov Identifier: NCT00083746 - Active, not recruiting
Spinal Muscular Atrophy
- DHEA Bioavailability Following Administration of Vaginal Suppositories in Post-Menopausal Women With Vaginal Atrophy
ClinicalTrials.gov Identifier: NCT00429806 - Active, not recruiting
Vaginal Atrophy
- Measuring Levels of SMN in Blood Samples of SMA Patients
ClinicalTrials.gov Identifier: NCT00061607 - Active, not recruiting
Spinal Muscular Atrophy
- A Pilot Theraputic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy Patients
ClinicalTrials.gov Identifier: NCT00568698 - Active, not recruiting
Muscular Atrophy, Spinal
- VG101 Phase I/II to Treat Vulvar and Vaginal Atrophy in Post-Menopausal Women
ClinicalTrials.gov Identifier: NCT00453089 - Not yet recruiting
Vaginal Atrophy; Vulvar Atrophy
- A Pilot Therapeutic Trial Using Hydroxyurea in Type II and III Spinal Muscular Atrophy Patients
ClinicalTrials.gov Identifier: NCT00084006 - Active, not recruiting
Spinal Muscular Atrophy
- Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy
ClinicalTrials.gov Identifier: NCT00227266 - Active, not recruiting
Spinal Muscular Atrophy
- A Pilot Theraputic Trial Using Hydroxyurea in Type II and Type III Spinal Muscular Atrophy Patients
ClinicalTrials.gov Identifier: NCT00568802 - Active, not recruiting
Muscular Atrophy, Spinal
- Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA)
ClinicalTrials.gov Identifier: NCT00303446 - Active, not recruiting
Kennedy's Disease; Spinal and Bulbar Muscular Atrophy
- A Clinical Study to Evaluate Ospemifene in the Treatment of Vulvar and Vaginal Atrophy in Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00276094 - Recruiting
Vulvar and Vaginal Atrophy in Postmenopausal Women
- Quantitative Analysis of SMN1 and SMN2 Gene Based on DHPLC System
ClinicalTrials.gov Identifier: NCT00155168 - Recruiting
Spinal Muscular Atrophy
- Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular Degeneration
ClinicalTrials.gov Identifier: NCT00429936 - Recruiting
Macular Degeneration; Atrophy
- A Randomized, Double-Blind, Placebo-Controlled Trial of Hydroxyurea in Spinal Muscular Atrophy
ClinicalTrials.gov Identifier: NCT00485511 - Recruiting
Spinal Muscular Atrophy
- Study to Evaluate Sodium Phenylbutyrate in Pre-Symptomatic Infants With Spinal Muscular Atrophy
ClinicalTrials.gov Identifier: NCT00528268 - Recruiting
Spinal Muscular Atrophy
- Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy
ClinicalTrials.gov Identifier: NCT00481013 - Recruiting
Spinal Muscular Atrophy
- Muscle Atrophy in Sepsis
ClinicalTrials.gov Identifier: NCT00583206 - Recruiting
Atrophy; Sepsis; Weakness
- Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Types II or III
ClinicalTrials.gov Identifier: NCT00439569 - Not yet recruiting
Spinal Muscular Atrophy Type II; Spinal Muscular Atrophy Type III
- Clinical Study of Spinal Muscular Atrophy
ClinicalTrials.gov Identifier: NCT00443066 - Recruiting
Spinal Muscular Atrophy
- OT-551 Antioxidant Eye Drops to Treat Geographic Atrophy in Age-Related Macular Degeneration
ClinicalTrials.gov Identifier: NCT00306488 - Recruiting
Bilateral Geographic Atrophy; Age-Related Macular Degeneration; AMD
- Establishing Novel Detection Techniques for Various Genetic-Related Diseases by Applying DHPLC Platform.
ClinicalTrials.gov Identifier: NCT00154960 - Recruiting
Spinal Muscular Atrophy; Neonatal Hyperbilirubinemia; Colon Cancer
- Effect of Exercise on Risk-Factors of Elderly Women
ClinicalTrials.gov Identifier: NCT00267839 - Active, not recruiting
Atrophy
- Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Type I
ClinicalTrials.gov Identifier: NCT00439218 - Not yet recruiting
Spinal Muscular Atrophy Type I
- A Clinical Trial to Evaluate the Safety and Efficacy of DR-2041 for Treatment of Vulvovaginal Atrophy
ClinicalTrials.gov Identifier: NCT00361569 - Active, not recruiting
Menopause
- Gene Therapy for Gyrate Atrophy
ClinicalTrials.gov Identifier: NCT00001735 - Completed
Gyrate Atrophy
- Study About Efficacy and Safety to Treat Multi-System-Atrophy
ClinicalTrials.gov Identifier: NCT00146809 - Completed
Multi-System-Atrophy; Minocycline
- International SMA Patient Registry
ClinicalTrials.gov Identifier: NCT00466349 - Recruiting
Muscular Atrophy, Spinal
- A Clinical Study to Evaluate the Safety of Ospemifene
ClinicalTrials.gov Identifier: NCT00566982 - Recruiting
Atrophy; Vaginal Diseases
- Combined Effects of Nutritional and Exercise Countermeasures
ClinicalTrials.gov Identifier: NCT00447044 - Recruiting
Muscular Atrophy; Muscle Weakness
- Gyrate Atrophy of the Choroid and Retina
ClinicalTrials.gov Identifier: NCT00001166 - Completed
Gyrate Atrophy
- Detection of Neural Loss in Patients With Permanent Temporal Visual Field Defect From Chiasmal Compression
ClinicalTrials.gov Identifier: NCT00553761 - Recruiting
Band Atrophy
- Safety and Effectiveness Study for Treating Older Men With Testosterone
ClinicalTrials.gov Identifier: NCT00475501 - Recruiting
Sarcopenia; Male Hypogonadism; Prostate Enlargement; Muscle Atrophy
- Phase II Study of Leuprolide and Testosterone for Men with Kennedy's Disease or Other Motor Neuron Disease
ClinicalTrials.gov Identifier: NCT00004771 - Completed
Spinal Muscular Atrophy; Amyotrophic Lateral Sclerosis; Spinobulbar Muscular Atrophy
- Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscular Atrophy
ClinicalTrials.gov Identifier: NCT00374075 - Completed
Spinal Muscular Atrophy
- Clinical Trial of Lamotrigine to Reverse Cognitive Impairment in Chronic Corticosteroid-Treated Patients
ClinicalTrials.gov Identifier: NCT00223262 - Active, not recruiting
Memory Impairment Due to Corticosteroid Use.; Hypomania Due to Corticosteroid Use.; Hippocampal Atrophy Due to Corticosteroid.
- Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease
ClinicalTrials.gov Identifier: NCT00324454 - Active, not recruiting
Motor Neuron Disease; Amyotrophic Lateral Sclerosis; Primary Lateral Sclerosis; Progressive Muscular Atrophy
- L-Dihydroxyphenylserine (L-DOPS) for Norepinephrine Deficiency: Interactions With Carbidopa and Entacapone
ClinicalTrials.gov Identifier: NCT00547911 - Recruiting
Parkinson Disease; Multiple System Atrophy; Autonomic Nervous System Diseases
- A Randomized, Double-Blind, Placebo-Controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)
ClinicalTrials.gov Identifier: NCT00528151 - Recruiting
Optic Atrophy, Hereditary, Leber
- Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly
ClinicalTrials.gov Identifier: NCT00018356 - Completed
Muscle Weakness; Muscular Atrophy
- Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy
ClinicalTrials.gov Identifier: NCT00103597 - Completed
Parkinson's Disease; Multiple System Atrophy; Orthostatic Hypotension
- Pilot Study of Growth Hormon to Treat SMA Typ II and III
ClinicalTrials.gov Identifier: NCT00533221 - Not yet recruiting
Muscular Atrophy, Spinal
- Effects of exercise on markers of inflammation in skeletal muscle in elderly hip fracture patients
ClinicalTrials.gov Identifier: NCT00006194 - Completed
Hip Fractures; Muscular Atrophy
- Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes
ClinicalTrials.gov Identifier: NCT00368199 - Recruiting
Parkinson's Disease; Parkinsonian Syndrome; Multiple System Atrophy; Supranuclear Palsy, Progressive; Essential Tremor; Vascular Parkinsonism; Drug Induced Parkinsonism
- The OMEGA Study: Use of Eye Drops to Treat Geographic Atrophy Associated With Age-Related Macular Degeneration (Dry AMD)
ClinicalTrials.gov Identifier: NCT00485394 - Recruiting
Age-Related Macular Degeneration
- Evaluating Muscle Function After Ankle Surgery
ClinicalTrials.gov Identifier: NCT00060970 - Completed
Muscle Atrophy; Muscle Weakness; Fractures
- Research of Biomarkers in Parkinson Disease
ClinicalTrials.gov Identifier: NCT00465790 - Not yet recruiting
Parkinson Disease; Multiple System Atrophy; Progressive Supranuclear Palsy; Huntington Disease; Dystonia; Diffuse Lewy Body Disease
- Diagnosis and Natural History Study of Patients with Neurological Conditions
ClinicalTrials.gov Identifier: NCT00001549 - Completed
Alzheimer's Disease; Dementia; Movement Disorder; Multiple System Atrophy; Parkinson's Disease
- Effect of Whole Body Vibration on Bone and Fall Related Parameters
ClinicalTrials.gov Identifier: NCT00292916 - Completed
Atrophy
- Optical Coherence Tomography Measurements in Eyes With Band Atrophy
ClinicalTrials.gov Identifier: NCT00395122 - Completed
Vision Disorders
- A Clinical Trial to Evaluate the Safety and Efficacy of Enjuvia 0.3 mg for the Treatment of Vulvovaginal Atrophy
ClinicalTrials.gov Identifier: NCT00196378 - Completed
Menopause
- Study Evaluating Bazedoxifene/Conjugated Estrogen Combinations in Vasomotor Symptoms Associated With Menopause
ClinicalTrials.gov Identifier: NCT00238732 - Completed
Vaginal Atrophy
- Efficacy Study Comparing 0.9 g and 1.25 g Estrogel With Placebo for Vasomotor Symptoms and Vulvar and Vaginal Atrophy
ClinicalTrials.gov Identifier: NCT00160173 - Completed
Postmenopausal Symptoms
- Neuroprotection and Natural History in Parkinson's Plus Syndromes (NNIPPS)
ClinicalTrials.gov Identifier: NCT00211224 - Terminated
Multiple System Atrophy; Progressive Supranuclear Palsy

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