The purpose of this study is to determine whether a gluten- and casein-free diet has specific benefits for children with autism.

Autism is a serious brain disorder that affects brain development and often causes social and educational problems. Studies suggest that a gluten- and casein-free diet may have a therapeutic effect on children with autism. This study will examine the effects of such a diet in autistic children.

Children in this study will be randomly assigned to follow either a gluten- and casein-free diet or a standard diet for 16 weeks. All participants will receive a supplement regimen, and educational and behavioral services will be provided. Standard autism evaluation methods, weekly diet and sleep diaries, and laboratory tests will be used to assess participants. A follow-up assessment will be completed 30 weeks after the start of the study.

Ages Eligible for Study:  30 Months   -   54 Months,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

• Autism spectrum disorder or pervasive developmental disorder
• Participation in applied behavioral analysis classes for at least 4 months, with at least 20 hours per week of service, and at least 1 hour of service in the home
• A score higher than 30 on the Mullen Early Learning scale
• Ability to maintain a gluten- and casein-free diet during the study
• In order to maintain study integrity, and due to frequent child assessments, enrollment is limited to a select population within the Rochester area