Thalassemia Clinical Trials

• Combined Chelation Treatment with Deferiprone and Deferoxamine in Thalassemia Major
  ClinicalTrials.gov Identifier: NCT00103753 - Active, not recruiting
  beta-Thalassemia
  
• Thalassemia Clinical Research Network - Cardiac L1/DFO Trial
  ClinicalTrials.gov Identifier: NCT00115349 - Recruiting
  Cardiovascular Diseases; Heart Diseases; Thalassemia; Anemia (Cooley''s); beta-Thalassemia
  
• Stem Cell Transplantation after Reduced-Dose Chemotherapy for Patients with Sickle Cell Disease or Thalassemia
  ClinicalTrials.gov Identifier: NCT00034528 - Active, not recruiting
  Hemoglobinopathies; Anemia, Sickle Cell; Hemoglobin SC Disease; Thalassemia; Thalassemia Major
  
• Extension Study on Efficacy and Safety of Deferasirox Treatment in Patients With Beta-Thalassemia and Transfusional Hemosiderosis
  ClinicalTrials.gov Identifier: NCT00171301 - Active, not recruiting
  Beta-Thalassemia Major
  
• Evaluating the Safety of Two Medications to Treat Hepatitis C in People With Thalassemia (The HepC Study)
  ClinicalTrials.gov Identifier: NCT00502788 - Active, not recruiting
  Hepatitis C; Thalassemia
  
• Genetic Factors Affecting the Severity of Beta Thalassemia
  ClinicalTrials.gov Identifier: NCT00159042 - Recruiting
  beta Thalassemia
  
• Genetics of Alpha Thalassemia in Israeli Ethnic Groups
  ClinicalTrials.gov Identifier: NCT00159029 - Recruiting
  alpha Thalassemia
  
• Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter
  ClinicalTrials.gov Identifier: NCT00481221 - Recruiting
  Thalassemia; Iron Deficiency
  
• Stem Cell Transplant in Patients With Thalassemia
  ClinicalTrials.gov Identifier: NCT00578292 - Recruiting
  Thalassemia
  
• Factors Promoting Increased Rate and Success of Pregnancy in the Thalassemia Population in Toronto
  ClinicalTrials.gov Identifier: NCT00327639 - Recruiting
  Thalassemia; Fertility; Pregnancy
  
• Cardiac T2* in Beta-Thalassemia Patients on Deferasirox Treatment
  ClinicalTrials.gov Identifier: NCT00447694 - Recruiting
  Beta-Thalassemia; Iron Overload
  
• Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia Major
  ClinicalTrials.gov Identifier: NCT00336362 - Recruiting
  Beta-Thalassemia
  
• Zinc to Improve Bone Health in People With Thalassemia (The Think Zinc Study)
  ClinicalTrials.gov Identifier: NCT00480415 - Recruiting
  Thalassemia
  
• Zinc & Bone Health in Thalassemia: The Think Zinc Study
  ClinicalTrials.gov Identifier: NCT00459732 - Recruiting
  Thalassemia
  
• Endocrine and Nutritional Assessment in B Thalassemia Major
  ClinicalTrials.gov Identifier: NCT00456690 - Not yet recruiting
  Thalassemia
  
• An Extension Study of Iron Chelation Therapy With Deferasirox in β-Thalassemia Patients With Transfusional Iron Overload
  ClinicalTrials.gov Identifier: NCT00171210 - Active, not recruiting
  Transfusional Iron Overload in β-Thalassemia
  
• Iron Chelation Therapy With Deferasirox in β-Thalassemia Major Pediatric Patients With Transfusional Iron Overload
  ClinicalTrials.gov Identifier: NCT00390858 - Active, not recruiting
  Transfusional Iron Overload in β-Thalassemia Major
  
• Phase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-Thalassemia Patients With Transfusional Iron Overload
  ClinicalTrials.gov Identifier: NCT00560820 - Recruiting
  β-Thalassemia; Transfusional Iron Overload
  
• L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia
  ClinicalTrials.gov Identifier: NCT00125788 - Active, not recruiting
  Sickle Cell Anemia (homozygous); Sickle ß0-Thalassemia
  
• Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)
  ClinicalTrials.gov Identifier: NCT00000623 - Completed
  Anemia (Cooley's); beta-Thalassemia; Blood Disease; Thalassemia; Osteoporosis
  
• Deferoxamine for the Treatment of Hemochromatosis
  ClinicalTrials.gov Identifier: NCT00001203 - Active, not recruiting
  Diabetes Mellitus; Heart Disease; Hemochromatosis; Thalassemia
  
• 5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia
  ClinicalTrials.gov Identifier: NCT00005934 - Completed
  Beta Thalassemia
  
• Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients with Hemoglobinopathies
  ClinicalTrials.gov Identifier: NCT00153985 - Recruiting
  Hemoglobinopathies; Sickle Cell Disease; Thalassemia
  
• Stem Cell Transplant in Sickle Cell Disease and Thalassemia
  ClinicalTrials.gov Identifier: NCT00408447 - Recruiting
  Sickle Cell Disease; Beta Thalassemia
  
• Safety & Efficacy of ICL670 vs. deferoxamine in Beta-thalassemia patients with iron overload due to blood transfusions
  ClinicalTrials.gov Identifier: NCT00061750 - Completed
  beta-Thalassemia
  
• Evaluation of Efficacy of Zoledronic Acid in Patients With Haemoglobin Syndromes (Thalassemia and Sicle Cell Anaemia) and Risk of Skeletal Events
  ClinicalTrials.gov Identifier: NCT00346242 - Completed
  Thalassemia
  
• Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia)
  ClinicalTrials.gov Identifier: NCT00001958 - Completed
  Beta Thalassemia; Hemoglobinopathy
  
• Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia Major
  ClinicalTrials.gov Identifier: NCT00006138 - Completed
  Osteoporosis; Thalassemia Major; Osteopenia
  
• L-glutamine Therapy for Sickle Cell Anemia
  ClinicalTrials.gov Identifier: NCT00029887 - Recruiting
  Anemia, Sickle Cell; Thalassemia
  
• Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major
  ClinicalTrials.gov Identifier: NCT00480506 - Completed
  Thalassemia Major
  
• Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis
  ClinicalTrials.gov Identifier: NCT00000595 - Completed
  Anemia (Iron-Loading); beta-Thalassemia; Hematologic Diseases; Hemoglobinopathies; Thalassemia; Iron Overload; Hemochromatosis
  
• Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload
  ClinicalTrials.gov Identifier: NCT00235391 - Active, not recruiting
  Thalassemia; Sickle Cell Disease; Diamond Blackfan Anemia; Myelofibrosis
  
• Phase I/II Study of Nonmyeloablative Allogeneic Bone Marrow Transplantation in Patients With High Risk Hemoglobinopathy
  ClinicalTrials.gov Identifier: NCT00005897 - Recruiting
  Graft Versus Host Disease; Sickle Cell Anemia; Thalassemia
  
• Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia
  ClinicalTrials.gov Identifier: NCT00512564 - Not yet recruiting
  Sickle Cell Anemia; Sickle Cell Thalassemia
  
• Iron Balance Study of DFO and GT56-252 in Patients with Transfusional Iron Overload Secondary to Beta-Thalassemia
  ClinicalTrials.gov Identifier: NCT00069862 - Completed
  beta-Thalassemia
  
• Efficacy Study in Removing Excess Iron from the Heart
  ClinicalTrials.gov Identifier: NCT00105495 - Completed
  Thalassemia Major; Hemosiderosis
  
• Chelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone
  ClinicalTrials.gov Identifier: NCT00000588 - Completed
  Anemia (Iron-Loading); beta-Thalassemia; Hematologic Diseases; Hemoglobinopathies; Thalassemia; Iron Overload
  
• A Study of Long-Term Treatment With Deferasirox in Patients With Beta-Thalassemia and Transfusional Hemosiderosis
  ClinicalTrials.gov Identifier: NCT00171171 - Completed
  Beta-Thalassemia; Hemosiderosis
  
• A Pilot Study of HSCT for Patients With High-Risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen
  ClinicalTrials.gov Identifier: NCT00427661 - Recruiting
  Sickle Cell Disease; Thalassemia; Hemoglobinopathies
  
• Stem Cell Transplant for Hemoglobinopathy
  ClinicalTrials.gov Identifier: NCT00176852 - Recruiting
  Sickle Cell Disease; Thalassemia
  
• Phase II Study of Arginine Butyrate With or Without Epoetin alfa in Patients With Thalassemia Intermedia
  ClinicalTrials.gov Identifier: NCT00006136 - Completed
  beta-Thalassemia
  
• Study of ICL670 in iron overload from beta-thalassemia unable to be treated with deferoxamine or chronic anemias
  ClinicalTrials.gov Identifier: NCT00061763 - Completed
  beta-Thalassemia; Myelodysplastic Syndromes; Fanconi Syndrome; Anemia, Diamond-Blackfan; Anemia, Aplastic
  
• Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia
  ClinicalTrials.gov Identifier: NCT00512226 - Not yet recruiting
  Sickle Cell Anemia; Sickle Cell Thalassemia; Iron Overload; MRI
  
• Extension Study of Iron Chelation Therapy With Deferasirox in β-Thalassemia and Other Patients With Rare Chronic Anemia and Transfusional Iron Overload
  ClinicalTrials.gov Identifier: NCT00303329 - Active, not recruiting
  Transfusional Iron Overload in Patients With Chronic Anemia
  
• Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-Thalassaemia Patients) With Chronic Iron Overload
  ClinicalTrials.gov Identifier: NCT00564941 - Not yet recruiting
  Myelodysplastic Syndromes; Beta-Thalassemia
  
• Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea
  ClinicalTrials.gov Identifier: NCT00480974 - Not yet recruiting
  Sickle Cell Anemia; Sickle Cell Thalassemia
  
• Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders
  ClinicalTrials.gov Identifier: NCT00005893 - Completed
  Neutropenia; Sickle Cell Anemia; Thalassemia Major; Red-Cell Aplasia, Pure
  
• Phase II Study of Azacitidine and Phenylbutyrate in Patients With Thalassemia Major
  ClinicalTrials.gov Identifier: NCT00007072 - Terminated
  Thalassemia Major
  
• Combination Iron Chelation Therapy
  ClinicalTrials.gov Identifier: NCT00004982 - Completed
  Iron Overload; Thalassemia
  
• Bone Marrow transplant from related donor for patients with high risk hemoglobinopathies
  ClinicalTrials.gov Identifier: NCT00040469 - Terminated
  Sickle Cell Anemia; Hemoglobinopathy; Thalassemia
  
• Invasive Infections in Children With Hemoglobinopathies
  ClinicalTrials.gov Identifier: NCT00456443 - Completed
  Thalassemia; Sickle Cell Anemia
  
• T2* in Transfusion Dependant Anemia, MI, LVF, Normal Patients
  ClinicalTrials.gov Identifier: NCT00520559 - Completed
  Thalassemia
  
• Bone marrow transplant from donor using less toxic conditioning for patient with high risk hemoglobinopathies
  ClinicalTrials.gov Identifier: NCT00040417 - Terminated
  Sickle Cell Anemia; Hemoglobinopathy; Thalassemia
  
• Stem Cell Transplantation (SCT) for Genetic Diseases
  ClinicalTrials.gov Identifier: NCT00004378 - Completed
  Thrombocytopenia; Metachromatic Leukodystrophy; Fanconi's Anemia; Thalassemia Major; Pure Red-Cell Aplasia; Inborn Errors of Metabolism