We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, produce both cardiomyopathy and muscular dystrophy. We are working to identify genes and gene mutations associated with cardiomyopathy, arrhythmias and muscular dystrophy. We propose to screen these samples for mutations in genes known to be involved in these disorders. New genes will be screened as they are identified from other research efforts.

Condition	Intervention
Cardiomyopathy Arrhythmia Muscular Dystrophy	Procedure: Blood draw (genetic testing)

Further Study Details: 

Expected Total Enrollment:  2000

Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

• Patients of all ages will be considered for the study. In particular, families with more than one affected relative will be sought.

Exclusion Criteria:

• Subjects without a suspected inherited cardiovascular or neuromuscular disorder will be excluded from this study.

Please refer to this study by ClinicalTrials.gov identifier  NCT00138931

Heather MacLeod, MS      773-702-4310    hmacleod@uchicago.edu
Elizabeth McNally, MD PhD      773-702-2679    emcnally@uchicago.edu

Illinois
      University of Chicago, Chicago,  Illinois,  60637,  United States; Recruiting

Study chairs or principal investigators

Elizabeth McNally, MD PhD,  Principal Investigator,  University of Chicago   

Study ID Numbers:  8249
Last Updated:  August 29, 2005
Record first received:  August 29, 2005
ClinicalTrials.gov Identifier:  NCT00138931
Health Authority: United States: Institutional Review Board
ClinicalTrials.gov processed this record on 2005-08-30