The purpose of this study is to determine if MR colonography with fecal tagging is better using air or water for distension of the colon. Patients referred to colonoscopy are offered MR colonography before colonoscopy. Two days before colonography, patients ingest a 200 ml Barium sulfate solution 2% four times a day, which will render fecal masses “invisible” on the following MR colonography. Air or water (randomised trial) is used for distension of the colon. The examinations are evaluated by two independent blinded readers.

Condition	Intervention	Phase
Colorectal Cancer Polyps	Procedure: MR colonography	Phase IV

Further Study Details: 

Primary Outcomes: Sensitivity/specificity for water versus air for distension of colon in MR colonography
Secondary Outcomes: Feasibility of MR colonography with fecal tagging; Sensitivity/specificity of MR colonography versus colonoscopy
Expected Total Enrollment:  60

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

• Suspicion of colorectal polyps or cancer
• Referred for colonoscopy

Exclusion Criteria:

• Suspicion of IBD
• Pacemaker
• Metal in the body
• Claustrophobia
• Pregnancy

Please refer to this study by ClinicalTrials.gov identifier  NCT00114842

Michael P Achiam, M.D.      +45 44884391    achiam1@dadlnet.dk

Denmark
      Department of Radiology Copenhagen University Hospital Herlev, Herlev,  DK-2730,  Denmark

Study chairs or principal investigators

Michael P Achiam, M.D.,  Principal Investigator,  Department of Radiology Copenhagen University Hospital Herlev   

Study ID Numbers:  KA05029-MA; KA05029
Record last reviewed:  May 2005
Last Updated:  June 30, 2005
Record first received:  June 17, 2005
ClinicalTrials.gov Identifier:  NCT00114842
Health Authority: Denmark: National Board of Health
ClinicalTrials.gov processed this record on 2005-07-05