Kidney disease in diabetes (diabetic nephropathy) tends to run in families. It is likely, therefore, that there are genes that predict or are associated with either getting or not getting diabetic nephropathy. The GoKinD Study will provide clinical information and DNA for investigators to look for these genes. Evaluation will be performed and DNA obtained from approximately 1100 diabetic persons with kidney disease and 1000 diabetic persons without kidney disease. In some cases, samples for DNA will also be obtained from the parents of these subjects. Clinical information and DNA will be coded so that individuals cannot be identified, but the DNA can be linked to the clinical data from the individual. Multiple investigators will be able to use this genetic material to test hypotheses about the genetics of kidney disease in diabetes.

Condition
Diabetic Nephropathy

Ages Eligible for Study:  18 Years   -   54 Years,  Genders Eligible for Study:  Both

Criteria

Inclusion criteria:

Type 1 diabetes mellitus with or without diabetic nephropathy; 19-54 years old; no other kidney disease

Missouri
      Washington University, St. Louis,  Missouri,  63110,  United States; Recruiting

Study ID Numbers:  NCRR-M01RR00036-0805
Record last reviewed:  December 2003
Last Updated:  October 13, 2004
Record first received:  October 5, 2001
ClinicalTrials.gov Identifier:  NCT00024921
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08