The purpose of this project is to lay the groundwork for a proposed clinical trial to compare the effectiveness of two approaches to gastroesophageal reflux disease: treatment with medications and treatment with anti-reflux surgery. This project includes a non-interventional pilot study to test ways of measuring outcomes of treatment, and to gauge potential participants' willingness to enroll in the proposed clinical trial.

Condition
Gastroesophageal Reflux

Ages Eligible for Study:  18 Years   -   80 Years,  Genders Eligible for Study:  Both

Criteria

Inclusion criteria:

• age 18-80
• diagnosis of gastroesophageal reflux disease
• have taken proton pump inhibitor medications

Exclusion criteria:

• prior esophageal surgery
• other serious medical conditions

Sam Finlayson, MD, MPH      603-650-8113    srgfinlayson@netscape.net

Illinois
      Hines VA Medical Center, Maywood,  Illinois,  United States; Recruiting
New Hampshire
      Dartmouth-Hitchcock Medical Center, Lebanon,  New Hampshire,  03756,  United States; Recruiting
North Carolina
      University of North Carolina, Chapel Hill,  North Carolina,  27599,  United States; No longer recruiting

Study ID Numbers:  MSTER
Record last reviewed:  January 2005
Last Updated:  January 4, 2005
Record first received:  June 3, 2003
ClinicalTrials.gov Identifier:  NCT00061724
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08