The primary goal of the Hutchinson Study of High School Smoking, a group-randomized trial conducted by the Fred Hutchinson Cancer Research Center in partnership with 50 Washington State high schools, is to develop and evaluate an innovative smoking cessation intervention to help teens succeed in quitting smoking. A positive finding would have significant implications for reducing youth smoking and, ultimately, improving the nation''''s health.

Condition	Intervention	Phase
Smoking cessation	Behavior: Motivational Interviewing and cognitive behavioral therapy	Phase III

Further Study Details: 

Primary Outcomes: 6-month smoking abstinence
Secondary Outcomes: 7-day, 1-month and 3-month smoking abstinence; number of quit attempts in past 12 months; longest length of time without smoking; change in readiness to quit; reduction in frequency/level of smoking
Expected Total Enrollment:  2886

Rates of smoking prevalence among US adolescents remain unacceptably high, with 24% of high school seniors smoking monthly and 16% smoking daily. Unfortunately, without intervention, for the majority of these adolescent smokers, smoking will be a long-term addiction. Recent studies have demonstrated that a majority of teen smokers want to quit and try to do so, but with little success.

The Hutchinson Study of High School Smoking is a 2-arm group-randomized trial in adolescent smoking cessation conducted by the Fred Hutchinson Cancer Research Center in partnership with 50 Washington State high schools. Twenty-five high schools are randomly assigned to the experimental (intervention) condition and 25 are assigned to the control (no intervention) condition. The trial uses innovative and rigorous trial design and methodology to address recruitment, retention, and other methodological challenges encountered in early adolescent cessation trials, to provide a rigorous test of in innovative proactive smoking cessation intervention. Participants are 2,886 high school students (all smokers and a sample of nonsmokers identified via baseline survey of all enrolled students at the end of their junior year).

The intervention, delivered during the senior year of high school, consists of a series of counselor-initiated, individually-tailored telephone counseling calls. Incorporating both Motivational Interviewing and cognitive behavioral strategies, the counseling telephone calls aim to increase smokers'''' motivation for quitting smoking, build skills for smoking cessation, and assist with relapse prevention. For nonsmokers, the telephone calls provide positive reinforcement of students'''' abstinence choices and help build skills for supporting peers'''' efforts to quit smoking. Complementary intervention components include an interactive cessation/informational Web site (www.Matchbreaker.org) and school-based promotional materials (cessation posters, school newspaper ads).

Participants are followed to endpoint, approximately 6 months post-high school, to assess the intervention''''s impact on cessation status, number of quit attempts, change in readiness to quit and reduction in frequency and level of smoking.

Ages Eligible for Study:  16 Years   -   20 Years,  Genders Eligible for Study:  Both

Accepts Healthy Volunteers

Criteria

Inclusion Criteria:

• All baseline survey respondents who smoke once a month or more and a sample of nonsmoker respondents (former smokers and never smokers with close friends who smoke)
• Written or verbal parental consent required for intervention participation by students under age 18

Exclusion Criteria:

• Enrolled in participating school at time of baseline survey, but not developmentally able to independently complete the baseline survey
• Not able to understand or speak English sufficiently to complete informed consent for telephone counseling
• Foreign exchange students

Washington
      Fred Hutchinson Cancer Research Center, Seattle,  Washington,  98109-1024,  United States

Study chairs or principal investigators

Arthur V. Peterson, Jr., PhD,  Principal Investigator,  Fred Hutchinson Cancer Research Center   

Study ID Numbers:  FHCRC IRB #4727; R01-CA82569
Last Updated:  June 30, 2005
Record first received:  June 26, 2005
ClinicalTrials.gov Identifier:  NCT00115882
Health Authority: United States: Institutional Review Board
ClinicalTrials.gov processed this record on 2005-08-02