Cardiac Biomarkers Clinical Trials

• Early Detection of Cardiotoxicity During Sunitinib or Sorafenib Chemotherapy Using Cardiac Biomarkers
  ClinicalTrials.gov Identifier: NCT00532064 - Recruiting
  Advanced Cancers
  
• Prognostic Value of New Cardiac Biomarkers in Elderly Patients Undergoing Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00416299 - Completed
  Cardiac Surgery
  
• Trial of Cardiac Magnetic Resonance Imaging (MRI) Versus Cardiac Catheterization prior to Glenn Operation
  ClinicalTrials.gov Identifier: NCT00112424 - Active, not recruiting
  Congenital Heart Defects
  
• Effects of Endurance Training on Patients With Reduced LVEF and Cardiac Resynchronisation Therapy Especially for Cardiac Arrhythmias
  ClinicalTrials.gov Identifier: NCT00472238 - Recruiting
  Heart Failure; Cardiac Resynchronisation Therapy; Sudden Cardiac Death
  
• Renal Safety of Everolimus in Addition to Cyclosporine Microemulsion in Cardiac Transplant Recipients.
  ClinicalTrials.gov Identifier: NCT00170794 - Active, not recruiting
  Cardiac Transplantation
  
• Tacrolimus: Protocol FKC-009 - Canadian Cardiology De Novo Study
  ClinicalTrials.gov Identifier: NCT00157014 - Active, not recruiting
  Heart transplantation; Cardiac transplantation; Transplantation, Cardiac; Transplantation, Heart; Grafting, Heart
  
• A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients with Cardiac Fabry Disease.
  ClinicalTrials.gov Identifier: NCT00140621 - Recruiting
  cardiac fabry disease
  
• Comparison of Aprotinin and Tranexamic Acid in Routine Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00396760 - Active, not recruiting
  Bleeding and Cardiac Surgery; Allogeneic Blood Transfusion; Aortic Valve Replacement; Coronary Artery Bypass Graft Surgery
  
• Using Minimally Invasive Cardiac Output Data Vs. Standard Care for Patients Emegently Admitted to the Intensive Care Unit Who Are Hemodynamically Unstable.
  ClinicalTrials.gov Identifier: NCT00354211 - Not yet recruiting
  Cardiac Output; Cardiac Output, High; Cardiac Output, Low; Hemodynamic Phenomena
  
• Internal Jugular Vein Ultrasound Measures and Fluid Responsiveness in Post-Operative Cardiac Surgical Patients
  ClinicalTrials.gov Identifier: NCT00500981 - Active, not recruiting
  Fluid Therapy; Cardiac Surgical Procedures
  
• Nurses Helping Sudden Cardiac Arrest Survivors Recover After Getting An Implantable Cardioverter Defibrillator (ICD)
  ClinicalTrials.gov Identifier: NCT00226681 - Active, not recruiting
  Sudden Cardiac Arrest
  
• Validation of Biomarkers of Exposure and Host Response
  ClinicalTrials.gov Identifier: NCT00468234 - Active, not recruiting
  Cigarette Smoker
  
• Dexamethasone for Cardiac Surgery Trial
  ClinicalTrials.gov Identifier: NCT00293592 - Recruiting
  Systemic Inflammatory Response Syndrome; Cardiac Diseases; Postoperative Complications
  
• The Use of Colloid Versus Crystalloid in Post-Operative Pediatric Cardiac Patients for Fluid Resuscitation
  ClinicalTrials.gov Identifier: NCT00464126 - Recruiting
  Cardiac Diseases
  
• Dual Chamber versus Single Chamber Cardiac Pacing in People 80 Years of Age and Older
  ClinicalTrials.gov Identifier: NCT00116987 - Recruiting
  Atrial Fibrillation; Cardiac Pacing, Artificial
  
• A Human in-Vivo Model for the Detection of Inflammatory and Nociceptive Biomarkers
  ClinicalTrials.gov Identifier: NCT00186563 - Active, not recruiting
  Inflammation
  
• Analysis of Aldehyde Biomarkers of Exposure and Host Response
  ClinicalTrials.gov Identifier: NCT00482690 - Active, not recruiting
  Smoking Cessation
  
• Analysis of Lipid Biomarkers of Exposure and Host Response
  ClinicalTrials.gov Identifier: NCT00493831 - Active, not recruiting
  Cigarette Smoking
  
• Effect of an Educational Intervention on Cardiac Patients' Participation Rate in Cardiac Rehabilitation Programs
  ClinicalTrials.gov Identifier: NCT00356863 - Recruiting
  Coronary Artery Disease
  
• EEG Biomarkers for Predicting Response to Antidepressant Therapy
  ClinicalTrials.gov Identifier: NCT00289523 - Active, not recruiting
  Major Depressive Disorder
  
• Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease
  ClinicalTrials.gov Identifier: NCT00555607 - Active, not recruiting
  Asthma; COPD
  
• Medications and the Risk of Sudden Cardiac Death
  ClinicalTrials.gov Identifier: NCT00241800 - Active, not recruiting
  Cardiovascular Diseases; Heart Diseases; Death, Sudden, Cardiac; Ventricular Fibrillation
  
• An Investigation of N-Acetylcysteine and Fenoldopam As Renal Protection Agents for Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00122018 - Active, not recruiting
  Kidney Failure, Acute; Kidney Failure, Chronic; Cardiac surgical procedures
  
• Effect of Targeting Left Ventricular Lead Position on the Rate of Response to Cardiac Resynchronization Therapy.
  ClinicalTrials.gov Identifier: NCT00399594 - Recruiting
  Heart Failure, Congestive; Cardiac Pacing, Artificial; Defibrillators
  
• p53 Vaccine in Treating Patients With Adenocarcinoma of the Ovary Who Have Either No Evidence of Disease or Elevated Biomarkers
  ClinicalTrials.gov Identifier: NCT00019903 - Active, not recruiting
  Ovarian Cancer
  
• Safety and Efficacy of the CryoCor™ Cardiac Cryoablation System for the Treatment of Atrial Flutter
  ClinicalTrials.gov Identifier: NCT00113178 - Active, not recruiting
  Atrial Flutter
  
• Comparison of Techniques for Assessing Cardiac Output and Preload in Critically Ill Pediatric Patients
  ClinicalTrials.gov Identifier: NCT00167440 - Recruiting
  Low Cardiac Output
  
• Automatic External Defibrillation Monitoring in Cardiac Arrest
  ClinicalTrials.gov Identifier: NCT00382928 - Recruiting
  Death, Sudden, Cardiac; Ventricular Fibrillation; Tachycardia, Ventricular
  
• A Clinical Pharmacological Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)
  ClinicalTrials.gov Identifier: NCT00525265 - Recruiting
  Cardiac Edema
  
• The Ability Of The PD2i Cardiac Analyzer To Predict Risk Of Ventricular Tachyarrhythmic Events
  ClinicalTrials.gov Identifier: NCT00510731 - Recruiting
  Tachycardia, Ventricular; Cardiac Sudden Death
  
• Post Operative Hemodynamic Function After Anesthetic Induction With Etomidate for Cardiac Surgery With ECC
  ClinicalTrials.gov Identifier: NCT00451776 - Recruiting
  Cardiac Surgery
  
• Peri-Operative And Long-Term Cardioprotective Properties Of Sevoflurane In High Risk Patients Undergoing Non-Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00336401 - Recruiting
  Non Cardiac Surgery
  
• Steroids In caRdiac Surgery Trial (SIRS Trial)
  ClinicalTrials.gov Identifier: NCT00427388 - Recruiting
  Cardiac Surgical Procedures; Cardiopulmonary Bypass; Systemic Inflammatory Response Syndrome
  
• Cerebral Bloodflow and Carbondioxide Reactivity During Mild Therapeutic Hypothermia in Patients After Cardiac Arrest
  ClinicalTrials.gov Identifier: NCT00441753 - Recruiting
  Cardiac Arrest; Post-Anoxic Encephalopathy
  
• A Double-Blind, Placebo-Controlled Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)
  ClinicalTrials.gov Identifier: NCT00462670 - Recruiting
  Edema, Cardiac
  
• Double Blind Randomized Trial of Saline vs Pentaspan for Resuscitation After Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00337805 - Recruiting
  Cardiac Surgery
  
• Study on the Repeatability of Cardiac Output Measurements Dependence of Temperature of Injectate
  ClinicalTrials.gov Identifier: NCT00464750 - Recruiting
  Thermodilution, Cardiac Output
  
• Fluid Shifts in Patients Treated With Therapeutic Hypothermia After Cardiac Arrest
  ClinicalTrials.gov Identifier: NCT00347477 - Recruiting
  Cardiac Arrest
  
• Biomarkers in Patients Undergoing Transrectal Ultrasound Prostate Biopsy
  ClinicalTrials.gov Identifier: NCT00373035 - Active, not recruiting
  Prostate Cancer
  
• Calcium, Vitamin D, and Colon Cancer Risk Biomarkers
  ClinicalTrials.gov Identifier: NCT00208793 - Active, not recruiting
  Colonic Polyps; Adenomatous Polyps
  
• Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00524472 - Recruiting
  Cardiac Surgery
  
• Comparing Angiomax to Heparin with Protamine Reversal in Patients OPCAB
  ClinicalTrials.gov Identifier: NCT00073593 - Active, not recruiting
  Cardiac Surgery; Coronary Artery Bypass Surgery
  
• Use of NovoSeven® in Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00154427 - Recruiting
  Post-operative bleeding following cardiac surgery
  
• Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest.
  ClinicalTrials.gov Identifier: NCT00358579 - Recruiting
  Cardiac Arrest
  
• Standard Drug Therapy vs. Implanted Defibrillator for Primary Prevention of Sudden Cardiac Death
  ClinicalTrials.gov Identifier: NCT00524862 - Not yet recruiting
  Coronary Heart Disease; Congestive Heart Failure; Ventricular Dysfunction; Low Cardiac Output; Sudden Cardiac Death
  
• Metabolic Signatures and Biomarkers
  ClinicalTrials.gov Identifier: NCT00466310 - Recruiting
  Schizophrenia
  
• Phase 3 Open-Label, Study of OPC-41061 in Subjects With Cardiac-Induced Edema (Congestive Heart Failure) — an Investigation of the Safety of Treatment Beyond 7 Days and the Effect of Dose Escalation to 30 mg
  ClinicalTrials.gov Identifier: NCT00544869 - Recruiting
  Cardiac Edema
  
• Goal-Orientated Therapy of Perioperative Disturbance in Hemostasis in Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00516126 - Recruiting
  Cardiac Surgery; Coronary Artery Bypass Graft; Hemostasis
  
• Cardiac Magnetic Resonance Imaging in Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma Receiving Doxorubicin
  ClinicalTrials.gov Identifier: NCT00577798 - Recruiting
  Cardiac Toxicity; Chemotherapeutic Agent Toxicity; Lymphoma
  
• Exploration Of Key Targets And Biomarkers Involved In An Allergic Response In Subjects With Allergic Rhinitis (Hay Fever)
  ClinicalTrials.gov Identifier: NCT00348361 - Active, not recruiting
  Allergic Rhinits
  
• Apoptic Biomarkers of Periodontal Disease
  ClinicalTrials.gov Identifier: NCT00569075 - Recruiting
  Periodontitis
  
• Optimize RV Selective Site Pacing Clinical Trial
  ClinicalTrials.gov Identifier: NCT00422669 - Recruiting
  Cardiac Pacing, Artificial; Cardiac Pacemaker, Artificial
  
• Pentastarch Use in Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00182377 - Recruiting
  Cardiac Surgery; Cardiopulmonary Bypass
  
• Increasing Walking Following Cardiac Rehabilitation
  ClinicalTrials.gov Identifier: NCT00281424 - Recruiting
  Cardiac Diseases; Walking
  
• OPALS Cardiac Arrest Database (OCAD)
  ClinicalTrials.gov Identifier: NCT00300703 - Recruiting
  Cardiac Arrest
  
• A Total Balanced Volume Replacement Regimen in Elderly Cardiac Surgery Patients
  ClinicalTrials.gov Identifier: NCT00576849 - Recruiting
  Elderly; Cardiac Surgery
  
• Assessing the Link Between Smoke Carcinogen Biomarkers and Lung Cancer Risk - 1
  ClinicalTrials.gov Identifier: NCT00218179 - Active, not recruiting
  Tobacco Use Disorder
  
• Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial
  ClinicalTrials.gov Identifier: NCT00401882 - Recruiting
  Cardiac Arrest; Sudden Cardiac Death; Ventricular Fibrillation; Tachycardia, Ventricular
  
• Safety and Feasibility of Endovascular Cooling Device in Patients with Hypothermic Cardiopulmonary Resuscitation
  ClinicalTrials.gov Identifier: NCT00154674 - Recruiting
  Cardiac Arrest
  
• Home Automatic External Defibrillator Trial -- HAT
  ClinicalTrials.gov Identifier: NCT00047411 - Active, not recruiting
  Cardiovascular Diseases; Myocardial Infarction; Heart Diseases; Death, Sudden, Cardiac
  
• 123I-MIBG SPECT/CT for Assessment of Cardiac Sympathetic Innervation
  ClinicalTrials.gov Identifier: NCT00296738 - Not yet recruiting
  Cardiac Diseases
  
• Randomized Trial of a Liberal Versus a Restrictive Transfusion Strategy in Elderly Cardiac Surgery Patients
  ClinicalTrials.gov Identifier: NCT00318227 - Recruiting
  Anemia; Postoperative Care; Cardiac Surgery; Coronary Artery Bypass Surgery; Blood Transfusion
  
• BONSAI: Biomarkers of Nonsteroidal Anti-Inflammatories
  ClinicalTrials.gov Identifier: NCT00239746 - Recruiting
  Alzheimer's Disease
  
• Biomarkers in the Diagnosis and Assessment of PAH
  ClinicalTrials.gov Identifier: NCT00566423 - Recruiting
  Pulmonary Arterial Hypertension
  
• Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk
  ClinicalTrials.gov Identifier: NCT00181233 - Recruiting
  Sudden Cardiac Death
  
• Evaluation of Patients With Non-Cardiac Chest Pain
  ClinicalTrials.gov Identifier: NCT00476398 - Recruiting
  Non-Cardiac Chest Pain; Gastroesophageal Reflux Disease
  
• Develop Biomarkers for Assessing RA Joint Erosion
  ClinicalTrials.gov Identifier: NCT00154947 - Active, not recruiting
  Rheumatoid Arthritis
  
• Genetic Determinants of Sudden Cardiac Death
  ClinicalTrials.gov Identifier: NCT00064558 - Active, not recruiting
  Cardiovascular Diseases; Heart Diseases; Death, Sudden, Cardiac; Ventricular Arrhythmia; Arrhythmia
  
• Selection of Shock Energy in Out-Of-Hospital Cardiac Arrest
  ClinicalTrials.gov Identifier: NCT00472147 - Not yet recruiting
  Sudden Cardiac Death; Arrhythmia; Survival
  
• Urinary Biomarkers as Predictors on Renal Function in Congenital Hydronephrosis
  ClinicalTrials.gov Identifier: NCT00568724 - Enrolling by invitation
  Congenital Hydronephrosis
  
• Registry of Unexplained Cardiac Arrest
  ClinicalTrials.gov Identifier: NCT00292032 - Recruiting
  Cardiac Arrest; Long QT Syndrome; Brugada Syndrome; Catecholamine Sensitive Polymorphic Ventricular Tachycardia; Idiopathic Ventricular Fibrillation
  
• Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00359398 - Recruiting
  Cardiac Surgical Procedures; Cardiopulmonary Bypass; Blood Platelet Disorders; Blood Coagulation Disorders
  
• Effects of Hesperidin on Bone Biomarkers in Postmenopausal Women
  ClinicalTrials.gov Identifier: NCT00545116 - Recruiting
  Osteopenia; Osteoporosis
  
• Study on the Efficacy and Mechanism of Cardiac Rehabilitation for Stem Cell Mobilization and Heart Failure Improvement
  ClinicalTrials.gov Identifier: NCT00154466 - Recruiting
  Myocardial Infarction
  
• A Pilot Study to Investigate Fenoldopam Usage in the Prevention of Postoperative Renal Dysfunction in Patients at a High Risk for Renal Impairment During Cariopulmonary Bypass for Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00467181 - Recruiting
  Cardiac Surgery With Cardiopulmonary Bypass
  
• Interest of Circulating Endothelial Biomarkers in Vascular Pregnancy Complications
  ClinicalTrials.gov Identifier: NCT00485784 - Recruiting
  Pre-Eclampsia
  
• Assessing the Variability Over Time of Tobacco Carcinogen Biomarkers in Smokers - 2
  ClinicalTrials.gov Identifier: NCT00158145 - Active, not recruiting
  Tobacco Use Disorder
  
• Angiomax in Patients with HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE)
  ClinicalTrials.gov Identifier: NCT00073580 - Active, not recruiting
  Thrombocytopenia; Thrombosis; Cardiac Disease; Coronary Artery Bypass Surgery
  
• Transfusion Triggers in Cardiac Surgery
  ClinicalTrials.gov Identifier: NCT00470444 - Recruiting
  Cardiac Surgery
  
• Nitrite as a Marker of Cardiovascular Risk: Development of Novel Biomarkers in Patients with Coronary Artery Disease
  ClinicalTrials.gov Identifier: NCT00109018 - Recruiting
  
  
• The Effect of Prophylactic Pre Operative Probiotic Therapy on Endotoxin Levels in Cardiac Surgery Patients
  ClinicalTrials.gov Identifier: NCT00256022 - Not yet recruiting
  Cardiac Surgery Patients.
  
• Investigation of Protein Biomarkers of Prostate Cancer
  ClinicalTrials.gov Identifier: NCT00323180 - Active, not recruiting
  Prostate Cancer
  
• Induction of Mild Hypothermia Following Out-of-Hospital Cardiac Arrest
  ClinicalTrials.gov Identifier: NCT00391469 - Recruiting
  Out-of-Hospital Cardiac Arrest
  
• Non-Cardiac Chest Pain Evaluation and Treatment Study (CARPA) - Part 1: Diagnosis.
  ClinicalTrials.gov Identifier: NCT00373828 - Recruiting
  Non-Cardiac Chest Pain; Undiagnosed Chest Pain; Musculoskeletal Chest Pain; Ischemic Heart Disease
  
• LOW CYCLO
  ClinicalTrials.gov Identifier: NCT00159159 - Active, not recruiting
  Cardiac transplant
  
• Chemotherapy in Treating Women Enrolled in the SWOG-8897 Clinical Trial
  ClinicalTrials.gov Identifier: NCT00002900 - Active, not recruiting
  stage I breast cancer; stage II breast cancer; ductal breast carcinoma; cardiac toxicity
  
• Effects of Epinephrine and Intravenous (I.V.) Needle On Cardiopulmonary Resuscitation (CPR) Outcome
  ClinicalTrials.gov Identifier: NCT00121524 - Recruiting
  Cardiac Arrest
  
• Effect of Intraoperative Aprotinin Administration on Post Cardiac Surgery Optic Nerve and Retinal Thickness.
  ClinicalTrials.gov Identifier: NCT00395369 - Not yet recruiting
  Cardiac Surgery
  
• Devitalized Non-Valved Pulmonary Artery Allograft Implant for the Repair of Congenital Cardiac Abnormalities
  ClinicalTrials.gov Identifier: NCT00411658 - Not yet recruiting
  Congenital Cardiac Abnormality
  
• Combination Chemotherapy and Radiation Therapy in Treating Children With Acute Lymphoblastic Leukemia
  ClinicalTrials.gov Identifier: NCT00004034 - Active, not recruiting
  L2 childhood acute lymphoblastic leukemia; untreated childhood acute lymphoblastic leukemia; cardiac toxicity; ...
  
• Effects of Allopurinol on Coronary and Peripheral Endothelial Function in Patients With Cardiac Syndrome X
  ClinicalTrials.gov Identifier: NCT00512057 - Not yet recruiting
  Cardiac Syndrome X
  
• Triage Now: an Observational, Prospective Multimarker Study of Biomarkers in Patients Presenting With Chest Pain
  ClinicalTrials.gov Identifier: NCT00380094 - Recruiting
  Acute Coronary Syndrome; Myocardial Infarction
  
• Study to Determine the Utility of Novel Technologies and Biomarkers to Measure Human Response to Rosiglitazone Maleate
  ClinicalTrials.gov Identifier: NCT00551564 - Recruiting
  Healthy; Overweight; Type 2 Diabetes Mellitus
  
• Pulse Contour Analysis and Tissue Oxymetry in Changing Vascular Tone
  ClinicalTrials.gov Identifier: NCT00583687 - Not yet recruiting
  Cardiac Output, High; Cardiac Output, Low; Vasodilation; Vasoconstriction; Hemodynamics
  
• Cardiac Water and Fluoromethane PET
  ClinicalTrials.gov Identifier: NCT00205127 - Active, not recruiting
  Healthy Volunteers
  
• OPALS Critical Care Sub-Studies
  ClinicalTrials.gov Identifier: NCT00212953 - Active, not recruiting
  Cardiac Arrest
  
• Identifying Methylation Biomarkers for Monitoring Bladder Tumors
  ClinicalTrials.gov Identifier: NCT00244205 - Recruiting
  Bladder Cancer
  
• Biomarkers in Patients With Rectal Cancer Undergoing Chemotherapy and Radiation Therapy
  ClinicalTrials.gov Identifier: NCT00280761 - Recruiting
  Colorectal Cancer
  
• Determining Disease Activity Biomarkers in Individuals With Giant Cell Arteritis
  ClinicalTrials.gov Identifier: NCT00315497 - Recruiting
  Temporal Arteritis
  
• Calcium/Vitamin D, Biomarkers,& Colon Polyp Prevention
  ClinicalTrials.gov Identifier: NCT00399607 - Recruiting
  Adenomatous Colon Polyps