CF Gene Mutation Clinical Trials

• Nasal Epithelial Cells/Blood Lymphocyte Markers for CF/CF Pulmonary Exacerbations
  ClinicalTrials.gov Identifier: NCT00381628 - Not yet recruiting
  Cystic Fibrosis
  
• Family Health After Predictive Huntington Disease (HD) Testing
  ClinicalTrials.gov Identifier: NCT00075140 - Recruiting
  Huntington Disease
  
• Clinical Study and Gene Mutation Analysis of Adrenoleukodystrophy in Taiwanese Children
  ClinicalTrials.gov Identifier: NCT00278044 - Recruiting
  Adrenoleukodystrophy
  
• Characteristics of Parkinson's Disease Associated With the LRRK-2 Gene Mutation
  ClinicalTrials.gov Identifier: NCT00467090 - Recruiting
  Parkinson Disease
  
• Telomere Repair Gene Mutation in Inflammatory Bowel Disease
  ClinicalTrials.gov Identifier: NCT00353639 - Active, not recruiting
  Inflammatory Bowel Disease; IBD
  
• Phase I Pilot Study of Gene Therapy for Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer
  ClinicalTrials.gov Identifier: NCT00004471 - Active, not recruiting
  Cystic Fibrosis
  
• Antimicrobial Resistance in CF
  ClinicalTrials.gov Identifier: NCT00360503 - Recruiting
  Cystic Fibrosis
  
• Mucin in Sputum of CF During Pulmonary Exacerbation
  ClinicalTrials.gov Identifier: NCT00202072 - Recruiting
  Cystic Fibrosis
  
• Effect of Simvastatin on CF Airway Inflammation
  ClinicalTrials.gov Identifier: NCT00255242 - Recruiting
  Cystic Fibrosis
  
• Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex
  ClinicalTrials.gov Identifier: NCT00298922 - Recruiting
  Cystic Fibrosis
  
• Effect of Azithromycin on Lung Function in 6-18 Year-Olds With CF Who Are Not Infected With Pseudomonas Aeruginosa
  ClinicalTrials.gov Identifier: NCT00431964 - Recruiting
  Cystic Fibrosis
  
• Factor V Leiden Mutation and Implantation Failure
  ClinicalTrials.gov Identifier: NCT00194350 - Active, not recruiting
  Infertility
  
• Study of LYM-X-SORB™ to Improve Fatty Acid and Choline Status in Children With CF and PI
  ClinicalTrials.gov Identifier: NCT00406536 - Recruiting
  Cystic Fibrosis; Pancreatic Insufficiency
  
• Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) with Advate (FLrFVIII) in Hemophilia A
  ClinicalTrials.gov Identifier: NCT00141843 - Active, not recruiting
  Hemophilia A
  
• First-Line Treatment for Adenocarcinoma Patients With EGFR Mutation
  ClinicalTrials.gov Identifier: NCT00344773 - Active, not recruiting
  Pulmonary Cancer
  
• Homoharringtonine in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation
  ClinicalTrials.gov Identifier: NCT00375219 - Recruiting
  Myeloid Leukemia, Chronic; Myeloid Leukemia, Chronic, Accelerated-Phase; Blast Phase; Myeloid Leukemia, Chronic, Chronic-Phase
  
• Trial of an Anti-HIV-1 Gene Transfer Product
  ClinicalTrials.gov Identifier: NCT00074997 - Active, not recruiting
  HIV Infections
  
• 18FDG- PET/CT Contribution to the Assessment of Lesion Severity in Cystic Fibrosis (CF)
  ClinicalTrials.gov Identifier: NCT00363402 - Recruiting
  Cystic Fibrosis
  
• Neoadjuvant Epirubicin, Cyclophosphamide, and Paclitaxel With or Without Gemcitabine in Treating Women With Early Breast Cancer
  ClinicalTrials.gov Identifier: NCT00070278 - Active, not recruiting
  stage II breast cancer; stage IIIA breast cancer; stage IIIB breast cancer; stage IIIC breast cancer
  
• Gene-Polymorphies in the P2X7 Gene in Patients With Osteoporotic Fractures
  ClinicalTrials.gov Identifier: NCT00293189 - Recruiting
  Hip Fracture
  
• Genetic Study to Identify Gene Mutations in Participants Previously Enrolled in Clinical Trial NCI-99-C-0053 Who Have von Hippel-Lindau Syndrome or Are at Risk for von Hippel-Lindau Syndrome
  ClinicalTrials.gov Identifier: NCT00075348 - Recruiting
  Renal Cell Cancer; von Hippel-Lindau Syndrome
  
• Study of TNFerade™ gene therapy, Radiation, 5-FU and Cisplatin in Esophageal Cancer
  ClinicalTrials.gov Identifier: NCT00051480 - Active, not recruiting
  Esophageal Cancer
  
• The Gene Expression Patterns in the Peripheral White Blood Cells of Type 2 Diabetic Patients
  ClinicalTrials.gov Identifier: NCT00155922 - Recruiting
  1. Diabetes mellitus; 2. Monocyte gene expression
  
• Gene Therapy and Surgery Followed by Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Cancer of the Mouth or Throat
  ClinicalTrials.gov Identifier: NCT00017173 - Active, not recruiting
  Hypopharyngeal Cancer; Laryngeal Cancer; lip and oral cavity cancer; Oropharyngeal Cancer
  
• Mutation Analysis of 17βhydroxysteroid Dehydrogenase 3 Deficiency
  ClinicalTrials.gov Identifier: NCT00173654 - Recruiting
  Pseudohermaphroditism
  
• Efficacy and Safety of ULTRASE MT20 in Improving the Coefficient of Fat Absorption (CFA%) in Children With Cystic Fibrosis (CF) and Pancreatic Insufficiency (PI)
  ClinicalTrials.gov Identifier: NCT00513682 - Recruiting
  Cystic Fibrosis; Pancreatic Insufficiency
  
• Study of Individuals and Families at High Risk for Cancer
  ClinicalTrials.gov Identifier: NCT00004007 - Recruiting
  Bladder Cancer; Brain and Central Nervous System Tumors; Lung Cancer; Non-Melanomatous Skin Cancer; Retinoblastoma; Sarcoma
  
• Chemotherapy With or Without Gene Therapy in Treating Patients With Unresectable Recurrent Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00040716 - Recruiting
  Head and Neck Cancer
  
• Mutation Analysis of 17α-Hydroxylase
  ClinicalTrials.gov Identifier: NCT00172510 - Recruiting
  Pseudohermaphroditism; Congenital Adrenal Hyperplasia; Hypertension
  
• Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
  ClinicalTrials.gov Identifier: NCT00001476 - Active, not recruiting
  Chronic Granulomatous Disease; Communicable Disease
  
• Gene Therapy in Treating Children With Refractory or Recurrent Neuroblastoma
  ClinicalTrials.gov Identifier: NCT00002748 - Active, not recruiting
  recurrent neuroblastoma
  
• Comparison of Gene Therapy With Chemotherapy in Treating Patients With Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00040703 - Recruiting
  Head and Neck Cancer
  
• Phase I Study of Adenoviral Vector Mediated Gene Transfer for Ornithine Transcarbamylase in Adults with Partial Ornithine Transcarbamylase Deficiency
  ClinicalTrials.gov Identifier: NCT00004498 - Active, not recruiting
  Ornithine Transcarbamylase Deficiency Disease
  
• Zinc Homeostasis and Kinetics in Children with Cystic Fibrosis (CF)
  ClinicalTrials.gov Identifier: NCT00104494 - Recruiting
  Cystic Fibrosis
  
• VEGF Gene Transfer for Diabetic Neuropathy
  ClinicalTrials.gov Identifier: NCT00056290 - Active, not recruiting
  Diabetic Neuropathy
  
• Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia
  ClinicalTrials.gov Identifier: NCT00005896 - Active, not recruiting
  Fanconi's Anemia
  
• Safety, Efficacy, Pharmacokinetics, Pharmacodynamics of ACZ885 in Patients With NALP3 Mutations and Clinical Symptoms
  ClinicalTrials.gov Identifier: NCT00487708 - Recruiting
  NALP3 Mutation
  
• Gene Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma
  ClinicalTrials.gov Identifier: NCT00003942 - Active, not recruiting
  AIDS-related diffuse small cleaved cell lymphoma; AIDS-related small noncleaved cell lymphoma; AIDS-related lymphoblastic lymphoma; ...
  
• Genetic Study in Patients with Advanced Epithelial Ovarian Cancer
  ClinicalTrials.gov Identifier: NCT00053235 - Not yet recruiting
  stage III ovarian epithelial cancer; stage IV ovarian epithelial cancer
  
• Gene Therapy in Treating Patients With Unresectable, Recurrent, or Refractory Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00004070 - Active, not recruiting
  lip and oral cavity cancer; Head and Neck Cancer; Oropharyngeal Cancer
  
• Standard Vs. Biofilm Susceptibility Testing in CF
  ClinicalTrials.gov Identifier: NCT00153634 - Recruiting
  Cystic Fibrosis; Chronic Bronchitis
  
• Biological Therapy and Gene Therapy in Treating Children With Recurrent or Refractory Neuroblastoma
  ClinicalTrials.gov Identifier: NCT00006480 - Active, not recruiting
  disseminated neuroblastoma; Drug Toxicity; recurrent neuroblastoma
  
• Behavioral & Nutritional Treatment to Help CF Preschoolers Grow
  ClinicalTrials.gov Identifier: NCT00241969 - Recruiting
  Cystic Fibrosis; Pancreatic Cystic Fibrosis
  
• Gene Therapy in Treating Patients With Recurrent or Progressive Glioblastoma Multiforme
  ClinicalTrials.gov Identifier: NCT00036725 - Active, not recruiting
  recurrent adult brain tumor; adult glioblastoma multiforme
  
• Cytokine Gene Polymorphisms in Bone Marrow Failure
  ClinicalTrials.gov Identifier: NCT00085670 - Active, not recruiting
  
  
• Blood T-Cells and EBV Specific CTLs Expressing GD-2 Specific Chimeric T Cell Receptors to Neuroblastoma Patients
  ClinicalTrials.gov Identifier: NCT00085930 - Recruiting
  Neuroblastoma
  
• Safety and Efficacy of Targeted Gene Transfer in Colorectal Cancer Metastatic to Liver
  ClinicalTrials.gov Identifier: NCT00035919 - Recruiting
  Colorectal Neoplasms
  
• Clinical, Molecular and Metabolic Characteristics of Parkinson's Disease (PD) Patients With Parkin Mutation
  ClinicalTrials.gov Identifier: NCT00169364 - Recruiting
  Parkinson's Disease
  
• The Chinese Mutation Hotspot of ENaC Causing Liddle’s Syndrome and the Association of ENaC Variations and Hypertension
  ClinicalTrials.gov Identifier: NCT00448162 - Recruiting
  Hypertension
  
• Telephone-Based Genetic Counseling or Standard Genetic Counseling in Women at Risk of Carrying the BRCA1 or BRCA2 Mutation
  ClinicalTrials.gov Identifier: NCT00287898 - Recruiting
  Breast Cancer
  
• Interferon-Induced Gene Expression in Liver Cells and Peripheral Blood Lymphocytes
  ClinicalTrials.gov Identifier: NCT00324389 - Active, not recruiting
  Hepatitis C
  
• Gene Therapy in Treating Patients With Cancer
  ClinicalTrials.gov Identifier: NCT00004178 - Active, not recruiting
  Lung Cancer; Pancreatic Cancer; Gastric Cancer; Salivary Gland Cancer; Renal Cell Cancer; Endometrial Cancer; Esophageal Cancer; Head and Neck Cancer; ...
  
• Gene Therapy in Treating Patients With Recurrent Head and Neck Cancer
  ClinicalTrials.gov Identifier: NCT00003257 - Active, not recruiting
  recurrent squamous cell carcinoma of the hypopharynx; recurrent squamous cell carcinoma of the larynx; ...
  
• Gene Therapy in Treating Patients With Advanced Recurrent or Persistent Ovarian Cancer or Primary Peritoneal Cancer
  ClinicalTrials.gov Identifier: NCT00003450 - Active, not recruiting
  recurrent ovarian epithelial cancer; peritoneal cavity cancer; stage IV ovarian epithelial cancer
  
• Gene Therapy for Prostate Cancer that Returns after Radiation Therapy
  ClinicalTrials.gov Identifier: NCT00110526 - Recruiting
  Prostatic Neoplasms; Neoplasm Recurrence, Local
  
• Gene Therapy in Patients With Colon Cancer That Has Spread to the Liver
  ClinicalTrials.gov Identifier: NCT00012155 - Active, not recruiting
  recurrent colon cancer; liver metastases; stage IV colon cancer; adenocarcinoma of the colon
  
• Safety and Efficacy Study of INGN 241 Gene Therapy in Patients with In Transit Melanoma
  ClinicalTrials.gov Identifier: NCT00116363 - Recruiting
  Malignant Melanoma; Neoplasm Metastasis
  
• Establishing the Incidences of BRCA1 and BRCA2 Mutation by Combining DHPLC and Direct Sequencing in Ovarian Cancer
  ClinicalTrials.gov Identifier: NCT00155896 - Recruiting
  Ovarian Cancer
  
• Virus-Specific Cytotoxic T-Lymphocytes (CTLs) for Adenovirus Infection Post Allogeneic Stem Cell Transplant
  ClinicalTrials.gov Identifier: NCT00111033 - Recruiting
  Adenovirus Infection
  
• Estrogen Receptor Gene Mutations
  ClinicalTrials.gov Identifier: NCT00342498 - Active, not recruiting
  Mutations; Hormones
  
• Cyclophosphamide and Fludarabine Followed By Interleukin-2 Gene-Modified Tumor Infiltrating Lymphocytes in Treating Patients With Metastatic Melanoma
  ClinicalTrials.gov Identifier: NCT00062036 - Active, not recruiting
  Melanoma (Skin)
  
• Gene-Modified White Blood Cells Followed By Interleukin-2 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
  ClinicalTrials.gov Identifier: NCT00085462 - Active, not recruiting
  Melanoma (Skin)
  
• A Phase IV Cross-Sectional Study of Prevalence of the I50L Mutation When ATV Treated Patients Fail the Regimen.
  ClinicalTrials.gov Identifier: NCT00135447 - Recruiting
  HIV/AIDS
  
• Pilot Study for the Determination of Tumor Response to Chemotherapy in Advanced NSCLC Through Gene Expression Profiling
  ClinicalTrials.gov Identifier: NCT00161278 - Recruiting
  Advanced Non-Small Cell Lung Cancer
  
• Cyclophosphamide and Fludarabine Followed by Vaccine Therapy, Gene-Modified White Blood Cell Infusions, and Aldesleukin in Treating Patients With Metastatic Melanoma
  ClinicalTrials.gov Identifier: NCT00091104 - Active, not recruiting
  Melanoma (Skin)
  
• The Relationship of Single Nucleotide Polymorphisms in the Interleukin-7 Receptor-α Gene to CD4+ Immune Recovery in HIV Infected Patients Who Begin Antiretroviral Treatment With HAART
  ClinicalTrials.gov Identifier: NCT00168207 - Active, not recruiting
  HIV Infections
  
• Study of the Results of Education and Counseling for Persons Undergoing Genetic Testing for Hereditary Nonpolyposis Colon Cancer
  ClinicalTrials.gov Identifier: NCT00004210 - Recruiting
  Colorectal Cancer
  
• Randomized Clinical Trial to Evaluate the Predictive Accuracy of a Gene Expression for Stage I-II Breast Cancer
  ClinicalTrials.gov Identifier: NCT00336791 - Active, not recruiting
  Breast Cancer
  
• Gene Expression Profiles in Predicting Chemotherapy Response in Breast Cancer
  ClinicalTrials.gov Identifier: NCT00212082 - Active, not recruiting
  Metastatic Breast Cancer
  
• The Influence of the 34C>T Variant in the AMPD1 Gene Ischemic Tolerance
  ClinicalTrials.gov Identifier: NCT00319059 - Active, not recruiting
  AMPD; Ischemic Tolerance
  
• Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)
  ClinicalTrials.gov Identifier: NCT00341146 - Active, not recruiting
  Nasopharyngeal Carcinoma
  
• An Interactive Program to Improve Care for Children With CF
  ClinicalTrials.gov Identifier: NCT00185549 - Completed
  Cystic Fibrosis
  
• Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
  ClinicalTrials.gov Identifier: NCT00005796 - Active, not recruiting
  Brain Tumor
  
• Genes Mutation Pentalogy of Cantrell
  ClinicalTrials.gov Identifier: NCT00477932 - Recruiting
  Pentalogy of Cantrell; Mutations in Non-Muscle Genes
  
• Safety Study of a Gene Transfer Vector for Children with Late Infantile Neuronal Ceroid Lipofuscinosis
  ClinicalTrials.gov Identifier: NCT00151216 - Recruiting
  Batten Disease; Late Infantile Neuronal Lipofuscinosis
  
• Mutation Screening and Translocation Detection of DISC1 Gene in Schizophrenia
  ClinicalTrials.gov Identifier: NCT00155818 - Completed
  Schizophrenia; Chinese Han People
  
• Mutation Screening and Translocation Detection of DISC1 Gene in Schizophrenia
  ClinicalTrials.gov Identifier: NCT00155701 - Completed
  Schizophrenia; Chinese Han People
  
• Interleukin-12 Gene in Treating Patients With Liver Metastases Secondary to Colorectal Cancer
  ClinicalTrials.gov Identifier: NCT00072098 - Recruiting
  stage IV colon cancer; Stage IV rectal cancer; liver metastases; recurrent rectal cancer; recurrent colon cancer
  
• Construction and Use of Lung Tumor Microarray for the Analysis of Gene Expression in Lung Cancer
  ClinicalTrials.gov Identifier: NCT00340847 - Active, not recruiting
  Lung Cancer
  
• Differences in Human Germinal Center B Cell Selection Revealed by Analysis of IgVH Gene Hypermutation and Lineage Trees in Inflammatory Bowel Disease
  ClinicalTrials.gov Identifier: NCT00291681 - Active, not recruiting
  Inflammatory Bowel Disease
  
• Whole Body Vibration - a New Therapeutic Approach to Improve Muscle Function in CF
  ClinicalTrials.gov Identifier: NCT00388466 - Completed
  Cystic Fibrosis
  
• Safety Study of Mini-Dystrophin Gene to Treat Duchenne Muscular Dystrophy
  ClinicalTrials.gov Identifier: NCT00428935 - Active, not recruiting
  Duchenne Muscular Dystrophy
  
• Irinotecan in Treating Patients With Colorectal Cancer
  ClinicalTrials.gov Identifier: NCT00003843 - Active, not recruiting
  stage IV colon cancer; Stage IV rectal cancer; recurrent colon cancer; recurrent rectal cancer
  
• Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma
  ClinicalTrials.gov Identifier: NCT00003793 - Active, not recruiting
  Ewing's family of tumors; childhood rhabdomyosarcoma; childhood soft tissue sarcoma; hematopoietic and lymphoid cancer; Osteosarcoma
  
• Safety and Efficacy of Pioglitazone as an Anti-Inflammatory for the Treatment of CF Lung Disease
  ClinicalTrials.gov Identifier: NCT00322868 - Completed
  Cystic Fibrosis
  
• Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
  ClinicalTrials.gov Identifier: NCT00377416 - Active, not recruiting
  Alpha 1-Antitrypsin Deficiency
  
• Treating High Risk Leukemia with CD40 Ligand & IL-2 Gene Modified Tumor Vaccine.
  ClinicalTrials.gov Identifier: NCT00058799 - Active, not recruiting
  Leukemia
  
• Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients with Intermittent Claudication
  ClinicalTrials.gov Identifier: NCT00117650 - Recruiting
  Intermittent Claudication; Peripheral Vascular Disease; Atherosclerosis
  
• Variation in Gene Expression in Neurofibromatosis Type 1
  ClinicalTrials.gov Identifier: NCT00111384 - Recruiting
  
  
• Follow-Up of Patients With Breast Cancer or Multiple Myeloma Previously Treated on a Gene Therapy Clinical Trial
  ClinicalTrials.gov Identifier: NCT00427726 - Active, not recruiting
  Breast Cancer; Multiple Myeloma and Plasma Cell Neoplasm
  
• Celiprolol in Patients With Ehlers-Danlos Syndrome, Vascular Type
  ClinicalTrials.gov Identifier: NCT00190411 - Active, not recruiting
  Ehlers-Danlos Syndrome, Type Iv, Autosomal Dominant; Gene Map Locus 2q31
  
• A Study of Patients with HER2 Gene Amplified Metastatic Breast Cancer Treated with First Line Herceptin and a Taxane
  ClinicalTrials.gov Identifier: NCT00097487 - Active, not recruiting
  Breast Cancer; Metastases
  
• Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions
  ClinicalTrials.gov Identifier: NCT00066404 - Active, not recruiting
  Cancer
  
• BDNF Gene Polymorphism and Antidepressants Treatment
  ClinicalTrials.gov Identifier: NCT00308893 - Recruiting
  Depression
  
• Gene Regulation by Thiazolidinediones
  ClinicalTrials.gov Identifier: NCT00567593 - Recruiting
  Inflammatory Bowel Disease
  
• Gene Therapy for the Treatment of Brain Tumors
  ClinicalTrials.gov Identifier: NCT00001328 - Active, not recruiting
  Brain Neoplasm; Neoplasm Metastasis
  
• To Find the Best Dose of pVGI.1(VEGF2) to Benefit Angina Patients when given with an Experimental Injection Catheter
  ClinicalTrials.gov Identifier: NCT00090714 - Active, not recruiting
  Angina Pectoris
  
• Gene Therapy for the Treatment of Fanconi's Anemia Type C
  ClinicalTrials.gov Identifier: NCT00001399 - Active, not recruiting
  Fanconi's Anemia; Pancytopenia
  
• Microarray Analysis of Gene Expression in IPF
  ClinicalTrials.gov Identifier: NCT00258544 - Recruiting
  Pulmonary Fibrosis
  
• VEGF Gene Transfer for Critical Limb Ischemia
  ClinicalTrials.gov Identifier: NCT00304837 - Active, not recruiting
  Critical Limb Ischemia; Ischemia; Leg Ulcer